Patents by Inventor Donald Hnatowich

Donald Hnatowich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacteriophage imaging of inflammation
    Publication number: 20050255043
    Abstract: Labeled bacteriophage are disclosed which are useful for detecting a bacterial infection in vivo.
    Type: Application
    Filed: April 8, 2005
    Publication date: November 17, 2005
    Inventors: Donald Hnatowich, Mary Rusckowski
  • Process for labeling amines with .sup.99m Tc
    Patent number: 4668503
    Abstract: Amines, including proteins and polypeptides covalently coupled with a chelating agent such as diethylenetriaminepentaacetic acid (DTPA) can be labeled with .sup.99m Tc in the presence of a stannous reducing agent at near neutral pH by maintaining the protein concentration at a low level and the DTPA concentration at a high level. The .sup.99m Tc is labeled to the protein through the DTPA sites linked to the protein. Utilizing .sup.111 In labeled proteins as controls, it is shown that the .sup.99m Tc labeled proteins are labeled at the DTPA sites and that they exhibit in vivo stabilities equal to that of the .sup.111 In labeled proteins.
    Type: Grant
    Filed: March 19, 1984
    Date of Patent: May 26, 1987
    Assignee: Trustees of University of Massachusetts
    Inventor: Donald Hnatowich