Abstract: Compositions comprising proanthocyanidin compositions (e.g. those extracted from cinnamomum species) that are observed to bind tau and inhibit its aggregation as well as methods for making and using such compositions are disclosed. In certain embodiments of the invention, the proanthocyanidins can be used as a probe to identify and/or characterize tau isoforms in a variety of contexts. In other embodiments of the invention, these compositions are used in methods designed to treat neurological disorders associated with tau aggregation (e.g. Alzheimer's disease).

Abstract: Method and apparatus for compressing or compacting junk vehicle bodies and the like is disclosed wherein a crushing machine has a frame with a generally horizontally disposed bed and a plurality of upright supports extending from the bed to at least one generally horizontal beam which connects the ends of the upright supports remote from the bed to form a generally rectangular framework with a longitudinal vehicle accepting aperture therethrough. A pair of arms are hinged to the frame at opposite sides of the opening and pivot between generally vertical and generally horizontal positions with a portion of one arm overlapping a portion of the other. The arms are actuated by hydraulic cylinders and are independently movable so that they may be overlapped in either order when in their horizontal positions.