Abstract: An ophthalmic blocking pad includes a foam layer, a film layer disposed over and directly contacting the foam layer, and an adhesive layer disposed over the film layer. The film layer has a tensile strength of at least about 25 ksi (172 MPa).

Abstract: An ophthalmic blocking pad includes a foam layer, a film layer disposed over and directly contacting the foam layer, and an adhesive layer disposed over the film layer. The film layer has a tensile strength of at least about 25 ksi (172 MPa).

Abstract: A transdermal drug delivery system is provided which includes an optionally crosslinked macromer-reinforced (meth)acrylic ester base copolymer pressure sensitive adhesive wherein the macromer includes repeat hydrophilic units.

Abstract: A pressure sensitive adhesive transdermal hormone delivery system is provided comprised of (1) a macromer reinforced (meth)acrylic ester base copolymer, and (2) a pharmacologically active agent in homogeneous admixture with said macromer-reinforced base copolymer, wherein the macromer contains hydrophilic repeat units

Abstract: A drug flux enhancer-tolerant pressure sensitive adhesive composition is provided comprised of a mixture of (1) a percutaneous penetration enhancer to increase permeability of skin to transdermally administered pharmacologically active agents and (2) a macromer reinforced base polymer, said base polymer comprising a phase separated graft copolymer composition comprised of copolymerized monomers A and B to form a backbone polymer having polymeric moieties grafted thereto, wherein monomer A is a monomeric acrylic or methacrylic ester of a non-tertiary alcohol having from 1 to 14 carbon atoms, with the average number of carbon atoms being in the range of about 4 to 12, and a monomer B is a polar monomer which is copolymerizable with monomer A.

Abstract: A water-absorbent pressure sensitive adhesive composition is provided comprising (a) a continuous phase comprised of a copolymer of a hydrophobic monomer and a hydrophilic monomer, said monomers being present in said copolymer in a weight ratio of from about 50:50 to about 90:10, respectively; and (b) a non-particulate discontinuous phase comprised of domains of a hydrophilic homopolymer or copolymer dispersed throughout said continuous phase.

Abstract: A novel polymeric pressure-sensitive adhesive formulation is provided comprised of a balanced hydrophilic/hydrophobic base polymer compounded with at least one water-soluble tackifying component. Upon contact of the pressure-sensitive adhesive with excess amounts of water, the water-soluble tackifying component is caused to separate from the base polymer, thus decreasing the ability of the base polymer to function as a pressure-sensitive adhesive. The adhesive may subsequently be easily removed from any substrate to which it has been applied.

Abstract: A novel polymeric pressure-sensitive adhesive formulation is provided comprised of a hydrophilic base polymer compounded with at least one water-soluble tackifying component. Upon contact of the pressure-sensitive adhesive with excess amounts of water, the water-soluble tackifying component is caused to separate from the base polymer, thus decreasing the ability of the base polymer to function as a pressure-sensitive adhesive. The adhesive may subsequently be easily removed from any substrate to which it has been applied.

Abstract: The present invention describes a pressure-sensitive hydrophilic laminate composite comprising contiguous layers of a tacky pressure sensitive hydrophilic polymer blend, and a non-tacky hydrophilic polymer blend. Numerous variations in individual layer formulations allow for a multitude of hydrophilic blend laminate composite structures, which are readily utilizable as wound dressings, and/or transdermal and topical delivery systems incorporating a wide range of bioactive agents. The hydrophilic laminate composite structurese are characterized by ease of application, adhesiveness to skin, high tensile strength, mechanical integrity, transparency, fluid absorbency, and highly effective bacterial barrier properties, and permeability to water vapor, oxygen and drugs and/or bioactive agents. In the preferred embodiments, they are further characterized in their ability to inhibit severe maceration of the wound as well as underlying tissue destruction upon removal.

Abstract: A tubular elastic sheath for a condom catheter, the sheath taking the form of a thin, flexible, cylindrical member of elastic material having inner and outer surfaces and being rolled outwardly upon itself to form a torus having successively larger turns. A thin, flexible, multi-layered tape is interposed between successive turns of the rolled torus with such layers, all adhering to each other and to the catheter member, comprising a first adhesive layer, a second adhesive layer, and a highly-stretchable elastomeric layer disposed between the first and second adhesive layers.

Abstract: A method of making a tubular elastic sheath having an adhesive-coated inner surface and particularly suitable for use as an external male catheter in a urine-collection system. In such method, the sheath is supported upon a mandrel and a flexible laminated tape, composed of first and second adhesive layers separated by an elastomeric layer, is placed in adhesive contact with the inner surface of the sheath or, alternatively, with its outer surface. Thereafter, the cylindrical body of the sheath is rolled upon the mandrel so that the tape is interposed between successive turns of the sheath, with the first adhesive layer in engagement with the sheath's inner surface and the second adhesive layer of the tape in contact with the sheath's outer surface.