Patents by Inventor Donald M. McDonald

Donald M. McDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cationic liposome delivery of taxanes to angiogenic blood vessels
    Publication number: 20100226970
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: February 10, 2010
    Publication date: September 9, 2010
    Inventors: Donald M. McDonald, John W. McLean, O. Gavin Thurston
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Patent number: 7494666
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: February 24, 2009
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baulk
  • Cationic liposome delivery of taxanes to angiogenic blood vessels
    Patent number: 7238369
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: July 3, 2007
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John W. McLean, O. Gavin Thurston
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Patent number: 7135192
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: November 14, 2006
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baulk
  • Cationic liposome delivery of taxanes to angiogenic blood vessels
    Patent number: 7112338
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: May 28, 2002
    Date of Patent: September 26, 2006
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John W. McLean, O. Gavin Thurston
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Patent number: 7094424
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: August 22, 2006
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Publication number: 20040192776
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: April 2, 2004
    Publication date: September 30, 2004
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baulk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Patent number: 6756055
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: June 29, 2004
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Publication number: 20040072795
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: November 3, 2003
    Publication date: April 15, 2004
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Publication number: 20030077305
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: November 22, 2002
    Publication date: April 24, 2003
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Publication number: 20020197306
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: November 14, 2001
    Publication date: December 26, 2002
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic liposome delivery of taxanes to angiogenic blood vessels
    Publication number: 20020168355
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: May 28, 2002
    Publication date: November 14, 2002
    Inventors: Donald M. McDonald, John W. McLean, O. Gavin Thurston
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Publication number: 20020155102
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Application
    Filed: May 29, 2002
    Publication date: October 24, 2002
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Patent number: 6120799
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: September 19, 2000
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Cationic lipid compositions targeting angiogenic endothelial cells
    Patent number: 5837283
    Abstract: Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: November 17, 1998
    Assignee: The Regents of the University of California
    Inventors: Donald M. McDonald, John McLean, O. Gavin Thurston, Peter Baluk
  • Use of formoterol for treatment of tissue injury
    Patent number: 5135954
    Abstract: Formoterol, a known .beta.-adrenergic agonist, which, when administered intravascularly, has been found to profoundly reduce plasma extravasation resulting from tissue damage consequent to injury induced, for example, by surgery.
    Type: Grant
    Filed: May 24, 1991
    Date of Patent: August 4, 1992
    Assignee: The Regents of the University of California
    Inventor: Donald M. McDonald
  • Maintenance alert system for heavy-duty trucks
    Patent number: RE39845
    Abstract: A real-time maintenance alert system and method for use in a heavy-duty truck having an engine controller with memory are provided. The system includes a sensor operative to indicate an engine condition from the group consisting of: oil filter restriction, air filter restriction, fuel filter restriction, oil level, and coolant reserve tank fluid level. Control logic at the engine controller processes the sensor signal to determine a real-time fault condition, when appropriate.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: September 18, 2007
    Assignee: Detroit Diesel Corporation
    Inventors: David Lawrence Hasfjord, Richard M. Avery, Jr., Dennis Michael Letang, James A. Gray, Donald M. McDonald, Marleen F. Thompson, Ian Daniel McKenzie, John Edward Longnecker