Patents by Inventor Donald M. Simons

Donald M. Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6140530
    Abstract: This invention relates to quinidine derivatives and immunogenic conjugates and reporter conjugates prepared therefrom. The immunogenic conjugates and reporter conjugates are useful for eliciting antibodies and for performing immunoassays for quinidine. A particle agglutination immunoassay for quinidine is also provided.
    Type: Grant
    Filed: March 27, 1997
    Date of Patent: October 31, 2000
    Assignee: Dade Behring Inc.
    Inventor: Donald M. Simons
  • Patent number: 5612221
    Abstract: Avidin-binding azo reagents which alter the spectrophotometric properties of avidin and the use of such reagents in homogeneous assays are described.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: March 18, 1997
    Assignee: Dade Chemistry Systems Inc.
    Inventors: Donald M. Simons, Susan Y. Tseng, Patricia C. Weber
  • Patent number: 5536820
    Abstract: Avidin-binding azo reagents which alter the spectrophotometric properties of avidin and the use of such reagents in homogeneous assays are described.
    Type: Grant
    Filed: June 23, 1994
    Date of Patent: July 16, 1996
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Donald M. Simons, Susan Y. Tseng, Patricia C. Weber
  • Patent number: 5332679
    Abstract: Immunoassays and DNA probe assays utilizing a non-immune, reversible binding displacement system are provided. In the assay, a releasable ligand, a binding partner for the releasable ligand, an analyte of interest, an analytically detectable (reporter) group, and at least one binding partner for the analyte, are first attached to an insoluble phase so as to form reporter-labeled complex bound to an insoluble phase, followed by the addition of a displacer ligand which displaces the releasable ligand along with some portion of the reporter-labeled complex, so that the released reporter is analytically detectable in a free liquid medium and can be related to the concentration of analyte in the sample.
    Type: Grant
    Filed: February 12, 1993
    Date of Patent: July 26, 1994
    Assignee: E. I. DuPont de Nemours and Company
    Inventors: Donald M. Simons, Susan Y. Tseng, David M. Obzansky
  • Patent number: 4952569
    Abstract: Estriol and estradiol glycidyl ethers, immunogenic conjugates thereof and processes for their preparation are provided. The immunogenic conjugates are useful for eliciting and purifying antibodies and in performing immunoassays for estriol and estradiol.
    Type: Grant
    Filed: December 2, 1985
    Date of Patent: August 28, 1990
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Donald M. Simons
  • Patent number: 4581337
    Abstract: Particle reagents, having polyether polyamine linking groups, for use in turbidimetric immunoassays are provided. These linking agents permit ready covalent attachment of compounds of biological interest to polymer particles and lead to immunoassays of improved precision.
    Type: Grant
    Filed: July 7, 1983
    Date of Patent: April 8, 1986
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: William A. Frey, Donald M. Simons
  • Patent number: 4328139
    Abstract: Certain filled propylene polymer compositions, especially propylene homopolymers filled with a carbon black (10-50 parts per 100 parts of polymer) and containing about 30-50 parts of intumescent fire-retardant obtained by heating a mixture of a polyol, a phosphorus acid, and melamine have very high ignition resistance and desirable physical properties. When usual inorganic fillers are used, instead of carbon black, good ignition resistance is not obtained. Carbonaceous materials other than carbon blacks, for example, acetylene blacks, graphite, and so-called Austin black reduce or completely counteract the fire-retardant activity of the intumescent fire retardant. Filled propylene polymer compositions of this invention are particularly suitable in applications where the fire hazard is particularly great, for example, in automotive parts under the hood and in electrical applications.
    Type: Grant
    Filed: October 27, 1980
    Date of Patent: May 4, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Donald M. Simons
  • Patent number: 4259230
    Abstract: Polypropylene compositions having high ignition resistance, flex modulus, and impact resistance are obtained by blending polypropylene homopolymer, a propylene/ethylene copolymer, an EPM or EPDM elastomer having an ethylene content of about 50-65 weight percent and a Mooney viscosity of 35-80, mica, a commercial chlorinated fire retardant, and antimony trioxide in defined proportions. These compositions are particularly suitable for electrical wire insulation and other applications where toughness, stiffness, and ignition resistance are important.
    Type: Grant
    Filed: September 26, 1979
    Date of Patent: March 31, 1981
    Assignee: E. I. Du Pont De Nemours and Company
    Inventor: Donald M. Simons