Patents by Inventor Donald Mark Sperbeck

Donald Mark Sperbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-Substituted 1,1-Dioxo- 1,2,5- Thiadiazolidin-3-One Derivatives
    Publication number: 20080139576
    Abstract: Compounds of the formula provide pharmacological agents which are inhibitors of PTPases, in particular, the compounds of formula I inhibit PTP-1B and TC PTP, and thus may be employed for the treatment of conditions associated with PTPase activity. The compounds of the present invention may also be employed for inhibition of other enzymes with a phosphotyrosine binding region such as the SH2 domain. Accordingly, the compounds of formula I may be employed for prevention or treatment of insulin resistance associated with obesity, glucose intolerance, diabetes mellitus, hypertension and ischemic diseases of the large and small blood vessels.
    Type: Application
    Filed: September 24, 2007
    Publication date: June 12, 2008
    Inventors: Gary Mark Coppola, John William Davies, Charles Francis Jewell, Yu-Chin Li, James Richard Wareing, Donald Mark Sperbeck, Travis Matthew Stams, Sidney Wolf Topiol, Isidoros Vlattas
  • 5-substituted 1,1-dioxo-1,2,5,-thiadiazolidin-3-one derivatives
    Patent number: 7291635
    Abstract: Compounds of the formula provide pharmacological agents which are inhibitors of PTPases, in particular, the compounds of formula I inhibit PTP-1B and TC PTP, and thus may be employed for the treatment of conditions associated with PTPase activity. The compounds of the present invention may also be employed for inhibition of other enzymes with a phosphotyrosine binding region such as the SH2 domain. Accordingly, the compounds of formula I may be employed for prevention or treatment of insulin resistance associated with obesity, glucose intolerance, diabetes mellitus, hypertension and ischemic diseases of the large and small blood vessels.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: November 6, 2007
    Assignee: Novartis AG
    Inventors: Gary Mark Coppola, John William Davies, Charles Francis Jewell, Jr., Yu-Chin Li, James Richard Wareing, Donald Mark Sperbeck, Travis Mathew Stams, Sidney Wolf Topiol, Isidoros Vlattas
  • Cyclic sulfamide derivatives and methods of use
    Publication number: 20040023974
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: April 2, 2003
    Publication date: February 5, 2004
    Inventors: Gary Mark Coppola, John William Davies, Charles Francis Jewell, Yu-Chin Li, James Richard Wareing, Donald Mark Sperbeck, Travis Matthew Stams, Sidney Wolf Topiol, Isidoros Vlattas