Patents by Inventor Donald McDonnell

Donald McDonnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAMKK2 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME
    Publication number: 20190167776
    Abstract: Provided herein are compositions including a CaMKK2 inhibitor and an anti-cancer therapeutic agent and methods of treating cancer in a subject by administering a therapeutically effective amount of the composition to a subject. The subject may be selected for treatment based on an immune cell measurement of a sample from the subject. Methods of treating cancer by administering a therapeutically effective amount of a CaMKK2 inhibitor, and administering a therapeutically effective amount of an anti-cancer therapeutic agent to the subject are also provided. Kits including combination of a CaMKK2 inhibitor and another anti-cancer therapeutic agent are also provided.
    Type: Application
    Filed: August 7, 2017
    Publication date: June 6, 2019
    Applicant: Duke University
    Inventors: Luigi RACIOPPI, Erik NELSON, Wei HUANG, Nelson CHAO, Donald MCDONNELL
  • Tetra-aryl cyclobutane inhibitors of androgen receptor action for the treatment of hormone refractory cancer
    Patent number: 9868705
    Abstract: The present disclosure provides tetra-substituted cyclobutane inhibitors of Androgen Receptor Action, and methods of using such inhibitors, for the treatment of hormone-refractory cancers.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: January 16, 2018
    Assignees: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, DUKE UNIVERSITY
    Inventors: John Katzenellenbogen, Donald McDonnell, John D. Norris, Alexander Parent, Julie Pollock, Jillian Gunther, Kathryn E. Carlson, Teresa Martin
  • Methods of treating hematological malignancies
    Publication number: 20070134349
    Abstract: The present invention relates, in general, to methods of treating malignancies and, in particular, to methods of treating hematological malignancies and to compositions suitable for use in such methods.
    Type: Application
    Filed: September 19, 2006
    Publication date: June 14, 2007
    Applicant: DUKE UNIVERSITY
    Inventors: Donald McDonnell, Michelle Jansen, Huey-Jing Huang