Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.

Abstract: A lift assembly 20 includes an enclosure 24 secured to the bottom floor F of the baggage compartment BC, a carriage 28 reciprocally mounted within the enclosure 24, and a lift platform 32 pivotally coupled to the carriage 28. The lift platform 32 may be equipped with a variety of safety features, such as a ramp barrier, a bridge barrier, a pair of handrails, and combinations thereof for providing protection and a sense of security for a passenger while on the lift platform.

Abstract: A drive assembly (100) for a wheelchair lift is provided. The drive assembly (100) includes an actuating assembly (104) in communication with a component of the wheelchair lift. The actuating assembly (104) is configured to selectively apply a driving force to move the component between at least first and second positions. The drive assembly (100) also includes an overload assembly (102) coupled to the actuating assembly (104). The overload assembly (102) is configured to redirect application of the driving force from the component to the overload assembly (102) when a force applied to the component exceeds a predetermined limit.

Abstract: The present invention relates to methods of sensitizing neoplastic cells to irradiation by using oncolytic viruses, particularly reoviruses. Also provided are methods of treating or ameliorating a tumor with a combination of oncolytic viruses and radiotherapy.

Abstract: The present invention discloses small compact motor systems which may be located inside a vehicle drive wheel, and which allow a drive motor to provide the necessary torque with reasonable system mass. The motor systems of the invention utilize polyphase electric motors, and are preferably connected to appropriate drive systems via mesh connections, to provide variable V/Hz ratios. In one embodiment the stator coils are wound around the inside and outside of the stator. In a further embodiment, the machine contains a high number of phases, greater than three. In a further embodiment, the phases are connected in a mesh connection. In a further embodiment, each half-phase is independently driven to enable second harmonic drive for an impedance effect. Improvements are apparent in efficiency and packing density.

Abstract: An afterburner apparatus that utilizes a novel swirl generator for rapidly and efficiently atomizing, vaporizing, as necessary, and mixing a fuel and an oxidant. The swirl generator converts an oxidant flow into a turbulent, three-dimensional flowfield into which the fuel is introduced. The swirl generator effects a toroidal outer recirculation zone and a central recirculation zone, which is positioned within the outer recirculation zone. These recirculation zones are configured in a backward-flowing manner that carries heat and combustion byproducts upstream where they are employed to continuously ignite a combustible fuel/oxidizer mixture in adjacent shear layers. The recirculation zones accelerate flame propagation to allow afterburning to be completed in a relatively short length.

Abstract: A method for managing memory usage in a computer system having a kernel and a kernel memory class. The method includes ascertaining a size of a base memory of the computer system, the base memory representing memory designated to be non-evacuable. The method also includes setting a size of the kernel memory class to be no larger than the size of the base memory. Requests for additional memory by a kernel process is evaluated at the evaluation stage and granted only if the additional memory, if granted, would not cause an amount of memory used by the kernel to exceed the size of the kernel memory class.

Abstract: A sensor, sensory array, and associated method for measuring a pressure are provided. The sensor includes a piezoelectric sensory device that is disposed on an electrically insulative substrate that can be adhered to a member for measuring the pressure on the member. The piezoelectric sensory device defines first and second contact surfaces and is adapted to provide an electric potential between the surfaces that corresponds to a pressure on the piezoelectric sensory device. Conductive terminals are in electrical communication with the piezoelectric sensory device and therefore also provide the electric potential indicative of the pressure on the surface of the test member. An electrically insulative sheet is disposed opposite the piezoelectric sensory device from the substrate. An electronic monitoring device can be electrically connected to the piezoelectric sensory device via the terminals and configured to monitor the electric potential provided by the piezoelectric sensory device.

Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.

Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.

Abstract: Oncolytic viruses can be used to purge cellular compositions to remove undesired neoplastic cells before the cellular compositions are used for transplantation. The present invention relates to the use of a virus to pre-treat a subject prior to delivery into the subject a transplant that has been purged with the same virus. This pre-treatment serves to elicit an immune response in the subject against the virus, thereby protecting the subject from infections by the virus after receiving the transplant, which likely contains infectious viruses.

Abstract: A ramjet powered device that utilizes a novel swirl generator for rapidly and efficiently atomizing, vaporizing, as necessary, and mixing a fuel into an oxidant. The swirl generator converts an oxidant flow into a turbulent, three-dimensional flowfield into which the fuel is introduced. The swirl generator effects a toroidal outer recirculation zone and an inner central recirculation zone, both of which are configured in a backward-flowing manner that carries heat and combustion byproducts upstream where they are employed to continuously ignite a combustible fuel/oxidizer mixture in adjacent shear layers and stabilizes flame propagation and accelerates combustion throughout the entire combustor. The swirl generator provides smooth combustion with no instabilities and minimum total pressure losses and enables significant reductions in the L/D ratio of the combustor. Other benefits include simplicity, reliability, wide flammability limits and high combustion efficiency and thrust performance.

Abstract: A combined-cycle engine having at least one core engine and at least one ramjet engine. The ramjet utilizes a novel swirl generator for rapidly and efficiently atomizing, vaporizing, as necessary, and mixing a fuel into an oxidant. The swirl generator converts an oxidant flow into a turbulent, three-dimensional flowfield into which the fuel is introduced. The swirl generator effects a toroidal outer recirculation zone and an inner central recirculation zone, both of which are configured in a backward-flowing manner that carries heat and combustion byproducts upstream where they are employed to continuously ignite a combustible fuel/oxidizer mixture in adjacent shear layers, which accelerate flame propagation throughout the core flowfield. The swirl generator provides smooth combustion with no instabilities and minimum total pressure losses and enables significant reductions in the L/D ratio of the combustor.

Abstract: The present invention relates to a method for removing neoplastic cells from a mixed cellular composition, which is outside of a living organism, by using a virus which selectively infect and kill neoplastic cell. A variety of viruses can be used in this method to remove neoplastic cells for different purposes, for example, to purge hematopoietic stem cells prior to transplantation. Also provided are compositions prepared according to this method, and kits comprising a combination of viruses which are useful in this invention.

Abstract: A lift assembly 20 includes an enclosure 24 secured to the bottom floor F of the baggage compartment BC, a carriage 28 reciprocally mounted within the enclosure 24, and a lift platform 32 pivotally coupled to the carriage 28. The lift platform 32 may be equipped with a variety of safety features, such as a ramp barrier, a bridge barrier, a pair of handrails, and combinations thereof for providing protection and a sense of security for a passenger while on the lift platform.

Abstract: A wheelchair ramp assembly (20) is disclosed. The wheelchair ramp assembly includes a frame attachable to a vehicle having a floor, a platform coupled to a portion of the frame, a ramp having a weight, and a reciprocating mechanism disposed between the ramp and the platform coupled to a portion of the frame, a ramp having a weight, and a reciprocating mechanism disposed between the ramp and the platform for reciprocating the ramp between a deployed position and a stowed position in response to a force. The reciprocating mechanism counterbalancing the weight of the ramp during actuation of the ramp between the deployed and stowed positions to reduce the force required to reciprocate the ramp between the deployed and stowed positions.

Abstract: The present invention relates to methods of sensitizing neoplastic cells to irradiation by using oncolytic viruses, particularly reoviruses. Also provided are methods of treating or ameliorating a tumor with a combination of oncolytic viruses and radiotherapy.

Abstract: The present invention provides a method for reducing pain associated with neoplasms in a mammal, comprising administering an effective amount of one or more oncolytic viruses. Preferably, the mammal also receives an analgesic, and the amount of analgesic required by the mammal is reduced when the oncolytic virus is administered. The oncolytic virus is preferably reovirus. The mammal may be additionally subject to other therapies, such as chemotherapy, immunotherapy, hormonal and/or radiation therapy.

Abstract: A wheelchair ramp assembly (20) is disclosed. The wheelchair ramp assembly includes a frame attachable to a vehicle having a floor, a platform coupled to a portion of the frame, a ramp having a weight, and a reciprocating mechanism disposed between the ramp and the platform coupled to a portion of the frame, a ramp having a weight, and a reciprocating mechanism disposed between the ramp and the platform for reciprocating the ramp between a deployed position and a stowed position in response to a force. The reciprocating mechanism counterbalancing the weight of the ramp during actuation of the ramp between the deployed and stowed positions to reduce the force required to reciprocate the ramp between the deployed and stowed positions.

Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.