Abstract: Binding members for alpha chain of receptor for granulocyte macrophage colony stimulating factor (GM-CSFR?), especially antibody molecules. Use of the binding members in treating inflammatory and autoimmune diseases, e.g. rheumatoid arthritis, asthma, allergic response, multiple sclerosis, myeloid leukaemia and atherosclerosis.

Abstract: A shear device is disclosed. The shear device includes a material guiding mechanism, a shear head including a shear blade disposed proximate the material guiding mechanism, and means for translating a first movement of one of the shear head and the material guiding mechanism into a second movement of the other of the shear head and the material guiding mechanism. A method is also disclosed.

Abstract: High affinity antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are effective in the inhibition of IL-13R?1-mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13R?1 activity. The present invention also discloses nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13R?1-mediated activities are also disclosed.

Abstract: In the operation of a generator by a source of mechanical power such as a spring motor delivering a variable amount of power to the generator a feedback circuit may be used to monitor the output of the generator. The feedback circuit is employed to provide an input back into the generator which serves to control the speed of rotation of the generator so that such speed is substantially constant. In the preferred embodiment disclosed the generator is an alternator and the frequency of the output of the alternator is monitored in the course of providing input back to the alternator.