Patents by Inventor Donald P. Kotler

Donald P. Kotler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5865763
    Abstract: Creatinine clearance is estimated in a patient by determining his or her body cell mass. In turn, the body cell mass of the patient is measured using bioimpedance analysis techniques. The patient's serum creatinine concentration is also measured. The body cell mass and the serum creatinine concentration provide an indication of actual creatinine clearance in the subject through use of a predictive formula. From this prediction, accurate dosages of potentially nephrotoxic medications can be appropriately prescribed.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: February 2, 1999
    Assignee: St. Luke's-Roosevelt Hospital
    Inventors: Donald P. Kotler, Emilia M. Sordillo
  • Patent number: 5840042
    Abstract: A method for predicting fat free mass (FFM) and total body water (TBW) of a prepubertal child infected with human immunodeficiency virus (HIV) comprises the steps of measuring a child's height, measuring the child's total body resistance, and predicting fat free mass (FFM) and total body weight (TBW) of said child using the measured height and total body resistance.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: November 24, 1998
    Assignee: St. Luke's-Roosevelt Hospital
    Inventors: Stephen M. Arpadi, Mary Horlick, Donald P. Kotler, Richard N. Pierson, John Thornton, Jack Wang
  • Patent number: 5722396
    Abstract: Creatinine clearance is estimated in a patient by determining his or her body cell mass. In turn, the body cell mass of the patient is measured using bioimpedance analysis techniques. The determined value of body cell mass is normalized by the height.sup.2 of the patient. The body cell mass or its normalized value provides an indication of actual creatinine clearance in the subject through use of a predictive formula. From this prediction, accurate dosages of potentially nephrotoxic medications can be appropriately prescribed.
    Type: Grant
    Filed: August 13, 1996
    Date of Patent: March 3, 1998
    Assignee: St. Luke's-Roosevelt Hospital Center
    Inventors: Donald P. Kotler, Emilia M. Sordillo
  • Patent number: 5615689
    Abstract: The inability to precisely estimate body composition using simple, inexpensive and easily applied techniques is an impediment to clinical investigations in nutrition. In this study, predictive equations for body cell mass (BCM), fat free mass (FFM), and total body water (TBW), were derived, using single frequency bioimpedance analysis (BIA), in 332 subjects, including white, black and hispanic men and women, both normal healthy controls and patients infected with the human immunodeficiency virus (HIV). Preliminary studies demonstrated more accurate predictions of BCM when using parallel transformed values of reactance than the values reported by the bioimpedance analyzer. Modeling equations derived after logarithmic transformation of height, reactance and impedance were more accurate predictors than equations using height.sup.2 /resistance, and the use of gender-specific equations further impoved accuracy.
    Type: Grant
    Filed: December 12, 1994
    Date of Patent: April 1, 1997
    Assignee: St. Luke's-Roosevelt Hospital
    Inventor: Donald P. Kotler
  • Patent number: 5106618
    Abstract: The invention comprises treatment of gastrointestinal disorders of parasitic protozoan and bacterial origin in immunocompromised and immunocompetent animals by administration hyperimmune milk products.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: April 21, 1992
    Assignee: Stolle Research and Development Corporation
    Inventors: Lee R. Beck, Donald P. Kotler