Abstract: An adjustable trunnion valve includes an obturator, a valve stem, at least one valve seal, and a trunnion. The trunnion and obturator are configured to translate the obturator along a longitudinal axis extending through the trunnion and the obturator upon rotation of the valve stem beyond one or both of its open position and its closed position. A method of operating an adjustable trunnion valve having an obturator coupled to a trunnion and a valve stem includes passing a fluid through the adjustable trunnion valve and rotating the valve stem to rotate the obturator about an axis of rotation and to simultaneously translate the obturator in a direction along the axis of rotation while the obturator is supported by the trunnion and while the fluid flows through the adjustable trunnion valve.

Abstract: An adjustable trunnion valve includes an obturator, a valve stem, at least one valve seal, and a trunnion. The trunnion and obturator are configured to translate the obturator along a longitudinal axis extending through the trunnion and the obturator upon rotation of the valve stem beyond one or both of its open position and its closed position. A method of operating an adjustable trunnion valve having an obturator coupled to a trunnion and a valve stem includes passing a fluid through the adjustable trunnion valve and rotating the valve stem to rotate the obturator about an axis of rotation and to simultaneously translate the obturator in a direction along the axis of rotation while the obturator is supported by the trunnion and while the fluid flows through the adjustable trunnion valve.

Abstract: A valve having secondary spring force containment includes a valve body featuring an opening with a valve closure member sized to close the opening. A stem has a first end connected to the valve closure member. A proximal spring seat is positioned adjacent to the valve body, A distal spring seat is mounted on the second end of the stem. A spring is positioned between the proximal and distal spring seats so that the valve closure member is urged into a position where the valve body opening is closed. A hollow rod is attached between the proximal and distal spring seats to provide secondary spring force containment with the stem passing through the hollow rod.

Abstract: A handle mechanism for a railway tank car includes a first turn prohibitor at the skid and a second turn prohibitor at the support bracket for an extension arm. The extension shaft is pivotally mounted to a stem adapter so that it can be displaced from the axis of rotation for the valve stem when the valve is in the closed position. The extension shaft must be aligned with the axis of rotation of the valve stem in order to allow the operator to turn the handle and consequently the extension shaft and valve stem to open the valve.

Abstract: A locking mechanism is provided for a tarping system having a flexible cover carried by a deployment mechanism having a horizontal arm spanning the width of a container, the deployment mechanism movable to an extended position in which the horizontal arm is adjacent one end of the container. The locking mechanism includes at least one locking element associated with one end of the container and at least one latching element having a latching portion configured to engage the at least one locking element. The latching element is pivotably supported on the horizontal arm so that latching element can pivot to and from a locked position in which the latching portion engages the at least one locking element. A tension element is connected between the latching element and the cover to control the pivoting of the latching element under the force of gravity based on the position of the flexible cover.

Abstract: A cover system for covering an open top of an open-topped container with a flexible cover includes a bail member having a first end pivotally connected to the container and an opposite second end connected to an end of the flexible cover, a hold-down bow member including an end portion pivotally connected to the bail member and an opposite end configured for bearing against the flexible cover, and a spring pack between the bail member and tensioning bow member.

Abstract: A locking mechanism is provided for a tarping system having a flexible cover carried by a deployment mechanism having a horizontal arm spanning the width of a container, the deployment mechanism movable to an extended position in which the horizontal arm is adjacent one end of the container. The locking mechanism includes at least one locking element associated with one end of the container and at least one latching element having a latching portion configured to engage the at least one locking element. The latching element is pivotably supported on the horizontal arm so that latching element can pivot to and from a locked position in which the latching portion engages the at least one locking element. A tension element is connected between the latching element and the cover to control the pivoting of the latching element under the force of gravity based on the position of the flexible cover.

Abstract: A cover system for covering an open top of an open-topped container with a flexible cover comprises a bail member having a first end pivotally connected to the container and an opposite second end connected to an end of the flexible cover, a tensioning bow member including an end portion pivotally connected to the bail member and an opposite end configured for bearing against the flexible cover, and a mechanism between the bail member and tensioning bow member including first and second members configured to cooperate to lock the tensioning bow member against movement relative to the bail member.

Abstract: A locking mechanism is provided for a tarping system having a flexible cover carried by a deployment mechanism having a horizontal arm spanning the width of a container, the deployment mechanism movable to an extended position in which the horizontal arm is adjacent one end of the container. The locking mechanism includes at least one locking element associated with one end of the container and at least one latching element having a latching portion configured to engage the at least one locking element. The latching element is pivotably supported on the horizontal arm so that that latching element can pivot to and from a locked position in which the latching portion engages the at least one locking element. A tension element is connected between the latching element and the cover to control the pivoting of the latching element under the force of gravity based on the position of the flexible cover.

Abstract: A cover system for covering an open top of an open-topped container with a flexible cover includes a bail member having a first end pivotally connected to the container and an opposite second end connected to an end of the flexible cover, a hold-down bow member including an end portion pivotally connected to the bail member and an opposite end configured for bearing against the flexible cover, and a spring pack between the bail member and tensioning bow member.

Abstract: A cover system for covering an open top of an open-topped container with a flexible cover comprises a bail member having a first end pivotally connected to the container and an opposite second end connected to an end of the flexible cover, a tensioning bow member including an end portion pivotally connected to the bail member and an opposite end configured for bearing against the flexible cover, and a mechanism between the bail member and tensioning bow member including first and second members configured to cooperate to lock the tensioning bow member against movement relative to the bail member.

Abstract: Methods of using monoclinic crystals of human beta-secretase (BACE) having unit cell dimensions of a, b, and c, wherein a is about 81±20 ? to about 101 ?, b is 103±20 ?, c is 100±20 ?, and ?=?=90°, and ? is 105°±10° for crystals of symmetry P21 and a=73.1, b=105.1, c=50.5 ? and ? is 94.8° for crystals of C2 symmetry in drug screening assays comprising selecting a potential modifier by adding the potential modifiers to an aqueous mixture of the crystal and detecting a measure of binding, such that the potential modifier that binds is selected as a potential drug.

Abstract: A locking mechanism is provided for a tarping system having a flexible cover carried by a deployment mechanism having a horizontal arm spanning the width of a container, the deployment mechanism movable to an extended position in which the horizontal arm is adjacent one end of the container. The locking mechanism includes at least one locking element associated with one end of the container and at least one latching element having a latching portion configured to engage the at least one locking element. The latching element is pivotably supported on the horizontal arm so that that latching element can pivot to and from a locked position in which the latching portion engages the at least one locking element. A tension element is connected between the latching element and the cover to control the pivoting of the latching element under the force of gravity based on the position of the flexible cover.

Abstract: A method of producing steel reinforced conveyor belting wherein the steel reinforcing cords are located in grooves formed between the mating faces of two layers of P.V.C. based material. The faces of the grooves are coated with an adhesive having a P.V.C. base including an epoxy resin and curing agent and the steel cords are adhered to the layers of P.V.C. by curing the assembly of cords and cover layers under heat and pressure.