Abstract: This is disclosed an endovascular prosthesis delivery system. The delivery system comprises an elongate delivery device comprising a delivery device longitudinal axis. The elongate delivery device is coupled to an endovascular prosthesis via a connection portion. The connection portion is configured to be detachable from the endovascular prosthesis or the delivery device upon application an electric current to the delivery device. The endovascular prosthesis in an unsheathed state and the elongate delivery device being rotatable with respect to one another about the delivery device longitudinal axis.

Abstract: In one of its aspects, the present invention relates to an endovascular prosthesis. The endovascular prosthesis includes a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against a vascular lumen and a retractable leaf portion attached to the first expandable portion. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion. Longitudinally adjacent pairs of rib portions are free of interconnecting struts. The endovascular prosthesis that can be unsheathed and re-sheathed for repositioning of the endovascular prosthesis prior to final deployment thereof. There is also described a delivery device that that is particularly well suited to delivering the present endovascular prosthesis through tortuous vasculature in the body.

Abstract: In one of its aspects, the present invention relates to an endovascular prosthesis. The endovascular prosthesis includes a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against a vascular lumen and a retractable leaf portion attached to the first expandable portion. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion. Longitudinally adjacent pairs of rib portions are free of interconnecting struts. The endovascular prosthesis that can be unsheathed and re-sheathed for repositioning of the endovascular prosthesis prior to final deployment thereof. There is also described a delivery device that that is particularly well suited to delivering the present endovascular prosthesis through tortuous vasculature in the body.

Abstract: There is disclosed a novel endovascular prosthesis that has an improved rotational range of proper placement of the prosthesis with respect to the opening of the aneurysm and provides improved flexibility with respect to longitudinal positioning of the device in the artery. This provides the clinician with a significant advantage over the prior art devices described above. The present elongate endovascular prosthesis comprises a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against the wall of the vascular lumen such as an artery. The endovascular prosthesis further comprises a retractable leaf portion attached to the first expandable portion; the retractable leaf portion serves to facilitate stasis and thrombotic occlusion of the aneurysm. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion.

Abstract: In one of its aspects, the present invention relates to an endovascular prosthesis. The endovascular prosthesis comprises a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against a vascular lumen and a retractable leaf portion attached to the first expandable portion. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion. Longitudinally adjacent pairs of rib portions are free of interconnecting struts. The endovascular prosthesis that can be unsheathed and re-sheathed for repositioning of the endovascular prosthesis prior to final deployment thereof. There is also described a delivery device that that is particularly well suited to delivering the present endovascular prosthesis through tortuous vasculature in the body.

Abstract: The present invention relates to an endovascular prosthesis. The endovascular prosthesis comprises a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against a vascular lumen and a retractable leaf portion attached to the first expandable portion. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion. In one preferred embodiment of the present endovascular prosthesis, the retractable leaf portion is configured such that a pair of ribs attached on opposite sides of a longitudinally straightened configuration of the spine portion in a plane of view normal to a central axis of the prosthesis defines a shape, in two dimensions, that is substantially non-circular.

Abstract: In one of its aspects, the present invention relates to an endovascular prosthesis. The endovascular prosthesis comprises a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against a vascular lumen and a retractable leaf portion attached to the first expandable portion. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion. Longitudinally adjacent pairs of rib portions are free of interconnecting struts. The endovascular prosthesis that can be unsheathed and re-sheathed for repositioning of the endovascular prosthesis prior to final deployment thereof. There is also described a delivery device that that is particularly well suited to delivering the present endovascular prosthesis through tortuous vasculature in the body.

Abstract: In one of its aspects, the present invention relates to an endovascular prosthesis. The endovascular prosthesis comprises a first expandable portion expandable from a first, unexpanded state to a second, expanded state to urge the first expandable portion against a vascular lumen and a retractable leaf portion attached to the first expandable portion. The retractable leaf portion comprises at least one spine portion and a plurality of rib portions attached to the spine portion. Longitudinally adjacent pairs of rib portions are free of interconnecting struts. The endovascular prosthesis that can be unsheathed and re-sheathed for repositioning of the endovascular prosthesis prior to final deployment thereof. There is also described a delivery device that that is particularly well suited to delivering the present endovascular prosthesis through tortuous vasculature in the body.

Abstract: An expandable stent comprising a proximal end and a distal end in communication with one another, a tubular wall disposed between the proximal end and the distal end, the tubular wall having a longitudinal axis and a porous surface defined by a plurality of interconnected struts, the interconnected struts comprising a gradient of strut thickness from a first end to a second end of the tubular wall, the stent being expandable from a first, contracted position to a second, expanded position upon the application of a radially outward force on the stent. The stent is ideally suited for applications in which a tortuous pathway must be followed to the stenosis or blockage and in which high radial rigidity of the expanded stent is required e.g., the treatment of ostial stenosis.

Abstract: A balloon dilation catheter comprising a tubular member having a proximal end and a distal end. An inflatable balloon is disposed at the distal end of the tubular member. A first lumen is disposed in the tubular member and in is communication with an interior of the inflatable balloon. A second lumen is disposed in the tubular member for receiving a guidewire substantially along a portion of its length. The second lumen has a first opening in the proximal region of the tubular member and a second opening at the distal region of the tubular member. A first slit is disposed longitudinally in the tubular member and extends along at least a portion of the tubular member, the first slit comprising a first pair of longitudinal edges in a side by side relationship.

Abstract: A endovascular prosthesis for implantation in a body passageway. The prosthesis comprises a tubular wall which is: (i) movable between a first longitudinal length and a second longitudinally length, and (ii) radially expandable for implantation of the prosthesis in the body passageway. In one embodiment, the tubular wall has a longitudinally length which is variable by an “accordion”-like action. In another embodiment, the tubular wall has a longitudinally length which is variable by an “telescoping”-like action. The longitudinal length of the tubular wall may be varied in vivo to optimize deployment of the endovascular prosthesis.

Abstract: A balloon dilation catheter comprising: a tubular member having a proximal end and a distal end and an inflatable balloon disposed at the distal end of the tubular member. The tubular member comprises a first lumen disposed in communication with an interior of the inflatable balloon and a second lumen for receiving a guidewire substantially along the entire length of the tubular member. The second lumen has a first opening at the proximal end of the tubular member and a second opening at the distal end of the tubular member. A first slit is disposed longitudinally from the first opening along substantially the entire length of the tubular member to permit separation of the guidewire with respect to the second lumen. The subject balloon dilation catheter provides improved rapid exchange advantages of either the catheter or the guidewire used in a catheterization technique.

Abstract: An expandable endovascular prosthesis comprising: body having a proximal end and a distal end; a first expandable portion disposed between the proximal end and the distal end, the tubular first expandable portion being expandable from a first, unexpanded state to a second, expanded state with a radially outward force thereon to urge the first expandable portion against a vascular lumen; and a second expandable portion attached to the first tubular expandable portion; the second expandable portion being expandable upon expansion of the tubular first expandable portion. The endovascular prosthesis is particularly useful in the treatment of aneurysms, particularly saccular aneurysms.

Abstract: An expandable dilation catheter advantageously useful to deliver and orient an endovascular prosthesis with respect to a target body passageway. The catheter comprises a first tubular member disposed in a proximal portion of the portion of the catheter and a second tubular member disposed in a distal portion of the catheter. The first tubular member and the second tubular member are in a spaced relationship with respect to one another. An expandable member (e.g., a balloon) is disposed distally of the second tubular member. A first lumen and a second lumen disposed in each of the first tubular member and in the second tubular member. The first lumen is in communication with an interior of the expandable member to function as an inflation lumen and the second lumen serves to receive a first guidewire. The first tubular member and second tubular member are interconnected by a coupling member.

Abstract: A balloon dilation catheter comprising: a tubular member having a proximal end and a distal end and an inflatable balloon disposed at the distal end of the tubular member. The tubular member comprises a first lumen disposed in communication with an interior of the inflatable balloon and a second lumen for receiving a guidewire substantially along the entire length of the tubular member. The second lumen has a first opening at the proximal end of the tubular member and a second opening at the distal end of the tubular member. A first slit is disposed longitudinally from the first opening along substantially the entire length of the tubular member to permit separation of the guidewire with respect to the second lumen. The subject balloon dilation catheter provides improved rapid exchange advantages of either the catheter or the guidewire used in a catheterization technique.

Abstract: A balloon dilation catheter comprising a tubular member having a proximal end and a distal end. An inflatable balloon is disposed at the distal end of the tubular member. A first lumen is disposed in the tubular member and in is communication with an interior of the inflatable balloon. A second lumen is disposed in the tubular member for receiving a guidewire substantially along a portion of its length. The second lumen has a first opening in the proximal region of the tubular member and a second opening at the distal region of the tubular member. A first slit is disposed longitudinally in the tubular member and extends along at least a portion of the tubular member, the first slit comprising a first pair of longitudinal edges in a side by side relationship.

Abstract: An endovascular sleeve which can be utilized to navigate a pair of guidewires to a bifurcated body passageway such that, once in place, the guidewires are substantially untwisted or untangled. This greatly facilitates delivery of the bifurcated stent to the bifurcated artery.

Abstract: An expandable stent having a proximal end and a distal end in communication with one another, and a tubular wall disposed between the proximal end and the distal end. The tubular wall has a longitudinal axis and a porous surface defined by a plurality of intersecting members comprising a series of longitudinal struts disposed substantially parallel to the longitudinal axis of the stent. Each longitudinal strut in the series comprises flexure members for substantially complementary extension and compression of a diametrically opposed pair of the longitudinal struts upon flexure of the stent. The flexure members may comprise first and second curved sections which are of a different size. At least one of the curved sections may comprise an arc of greater than about 180°.

Abstract: An expandable stent having a proximal end and a distal end in communication with one another, and a tubular wall disposed between the proximal end and the distal end. The tubular wall has a longitudinal axis and a porous surface defined by a plurality of intersecting members comprising a series of longitudinal struts disposed substantially parallel to the longitudinal axis of the stent. Each longitudinal strut in the series comprises flexure members for substantially complementary extension and compression of a diametrically opposed pair of the longitudinal struts upon flexure of the stent. The flexure members may comprise first and second curved sections which are of a different size. At least one of the curved sections may comprise an arc of greater than about 180°.

Abstract: An expandable endovascular prosthesis comprising: body having a proximal end and a distal end; a first expandable portion disposed between the proximal end and the distal end, the tubular first expandable portion being expandable from a first, unexpanded state to a second, expanded state with a radially outward force thereon to urge the first expandable portion against a vascular lumen; and a second expandable portion attached to the first tubular expandable portion; the second expandable portion being expandable upon expansion of the tubular first expandable portion. The endovascular prosthesis is particularly useful in the treatment of aneurysms, particularly saccular aneurysms.