Abstract: A configurable clamp assembly for retaining pipe, conduit, cable bundles, waveguides and fiber optic cable that is designed for rapid installation without the need of pre-drilled holes or other mounting surface preparation. The clamp is formed by a saddle structure with integral rectangular flat base plate that receives interchangeable mounting pads and either a securing fastener or adhesive layer that secures the clamp to a mounting surface. A clamping yoke is hingedly secured to the saddle structure that is adapted to fold about the hinge to enclose and retain pipes, conduits or a Collar that engages an interchangeable Insert. The clamping yoke is fastened with a locknut that engages a threaded retaining post, locking the yoke to the saddle. The Insert is provided with various cross section geometries to secure waveguides, fiber optic cables and specially shaped tubing and is designed for insertion into the Collar for special applications.