Patents by Inventor Donald S. Coffey

Donald S. Coffey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid ligands to the prostate specific membrane antigen
    Patent number: 6933114
    Abstract: Methods are provided for generating nucleic acid ligands of Prostate Specific Membrane Antigen (PSMA). The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to PSMA, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: August 23, 2005
    Assignee: Gilead Sciences, Inc.
    Inventors: Shawn E. Lupold, Yun Lin, Brian J. Hicke, Donald S. Coffey
  • Nuclear matrix proteins
    Publication number: 20030143621
    Abstract: Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
    Type: Application
    Filed: January 29, 2003
    Publication date: July 31, 2003
    Applicant: THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Donald S. Coffey, Alan W. Partin, Robert H. Getzenberg
  • NUCLEAR MATRIX PROTEINS
    Publication number: 20020168695
    Abstract: Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
    Type: Application
    Filed: October 20, 1998
    Publication date: November 14, 2002
    Inventors: DONALD S. COFFEY, ALAN W. PARTIN, ROBERT H. GETZENBERG
  • Nucleic acid ligands to the prostate specific membrane antigen
    Publication number: 20020119473
    Abstract: Methods are provided for generating nucleic acid ligands of Prostate Specific Membrane Antigen (PSMA). The methods of the invention use the SELEX method for the isolation of nucleic acid ligands. The invention also includes nucleic acid ligands to PSMA, and methods and compositions for the treatment and diagnosis of disease using the nucleic acid ligands.
    Type: Application
    Filed: October 16, 2001
    Publication date: August 29, 2002
    Inventors: Shawn E. Lupold, Yun Lin, Brian J. Hicke, Donald S. Coffey
  • Nuclear matrix proteins
    Patent number: 6030793
    Abstract: Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: February 29, 2000
    Assignee: The John Hopkins University School of Medicine
    Inventors: Donald S. Coffey, Alan W. Partin, Robert H. Getzenberg
  • Antibodies to nuclear matrix proteins
    Patent number: 5874539
    Abstract: Antibodies directed to nuclear matrix proteins (NMP) are provided. Such antibodies are useful markers in diagnosing and monitoring the stage of malignancy of a cell.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 23, 1999
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Donald S. Coffey, Alan W. Partin, Robert H. Getzenberg
  • Nuclear matrix proteins
    Patent number: 5849509
    Abstract: Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 15, 1998
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Donald S. Coffey, Alan W. Partin, Robert H. Getzenberg
  • Method for detecting prostate cancer using a reagent which binds prostate cancer-1 protein
    Patent number: 5824490
    Abstract: Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. Also provided is an in vitro method for detecting prostate cancer in a sample employing a reagent that reacts with the NMP designated PC-1 (prostate cancer-1).
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 20, 1998
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Donald S. Coffey, Alan W. Partin, Robert H. Getzenberg