Abstract: A dynamically configurable ultrasound transducer element and related circuits and methods. The transducer may comprise an array of capacitive transducer elements, a row decoder coupled to said array of capacitive transducer elements, a column decoder coupled to said array of capacitive transducer elements, a bias voltage source coupled to said row decoder, and a driving signal source coupled to said column decoder. Preferably, a master clock also is provided to allow for a synchronization of signals between the row decoder and column decoder.

Abstract: The present invention provides ultrasound imaging catheters, systems and methods for their use which will be particularly useful to monitor the positioning of ablation catheters. In one embodiment, an imaging catheter (10) includes a catheter body (11) having a distal end (12), a proximal end (14) and a longitudinal axis (16). A transducer (20) is rotatably coupled to the distal end. The transducer has an axis of rotation (24) that is at a non-zero angle relative to the catheter body longitudinal axis. Such a configuration provides an exemplary side-looking imaging catheter.

Abstract: A catheter assembly includes an elongate catheter body having a proximal end and a distal end with a drive cable disposed therein, the drive cable having a proximal end and a distal end, and rotatable relative to the catheter body. A first electro-magnetic element is disposed proximate the distal end of the catheter, and a second electro-magnetic element disposed proximate the distal end of the drive cable and in electrical communication with an operative element mounted at the end of the drive cable, the first and second electro-magnetic elements forming an inductive coupler. The catheter assembly can include various other distal operative elements, which are in communication with corresponding proximal operative elements via transmission lines embedded within the wall of the catheter body.

Abstract: A dynamically configurable ultrasound transducer element and related circuits and methods. The transducer may comprise an array of capacitive transducer elements, a row decoder coupled to said array of capacitive transducer elements, a column decoder coupled to said array of capacitive transducer elements, a bias voltage source coupled to said row decoder, and a driving signal source coupled to said column decoder. Preferably, a master clock also is provided to allow for a synchronization of signals between the row decoder and column decoder.

Abstract: Rotating element catheters employ clutch assemblies for preventing rotational energy from being transmitted from a motor drive unit to the catheter element under defined circumstances. The catheter assembly includes an elongate member in which there is disposed a rotatable catheter drive cable. To control the rotation of the catheter drive shaft, the clutch assembly is configured to allow the catheter drive shaft to rotate and to stop rotating. The clutch assembly includes a driven member and a driver member, which cooperate with each other, such that the driven and driver members are rotatably engaged with each other before an applied torque exceeds the critical magnitude, rotatably unengaged with each other after the applied torque exceeds the critical magnitude, and rotatably re-engaged when the applied torque falls substantially below the critical magnitude. This clutching function can be actuated by any of a variety of physical forces, e.g., frictionally or magnetically.

Abstract: A dynamically configurable ultrasound transducer element and related circuits and methods. The transducer may comprise an array of capacitive transducer elements, a row decoder coupled to said array of capacitive transducer elements, a column decoder coupled to said array of capacitive transducer elements, a bias voltage source coupled to said row decoder, and a driving signal source coupled to said column decoder. Preferably, a master clock also is provided to allow for a synchronization of signals between the row decoder and column decoder.

Abstract: An intravascular imaging guidewire which can accomplish longitudinal translation of an imaging plane allowing imaging, by acoustic or light energy, of an axial length of a region of interest without moving the guidewire. The imaging guidewire comprises a body in the form of a flexible elongate tubular member. An elongate flexible imaging core is slidably received within the body. The imaging core includes a shaft having an imaging device mounted on its distal end. The body and the imaging core are cooperatively constructed to enable axial translation of the imaging core and imaging device relative to the body. The body has a transparent distal portion extending an axial length over which axially translatable imaging may be performed. The imaging guidewire has a maximum diameter over its entire length sized to be received within a guidewire lumen of an intravascular catheter.

Abstract: An intravascular imaging guidewire which can accomplish longitudinal translation of an imaging plane allowing imaging, by acoustic other high quality imaging energy, of an axial length of a region of interest without moving the guidewire. The imaging guidewire comprises a body in the form of a flexible elongate tubular member. An elongate flexible imaging core is slidably received within the body. The imaging core includes a shaft having an imaging device mounted on its distal end. The body and the imaging core are cooperatively constructed to enable axial translation of the imaging core and imaging device relative to the body. The body has a transparent distal portion extending an axial length over which axially translatable imaging may be performed. The imaging guidewire has a maximum diameter over its entire length sized to be received within a guidewire lumen of an intravascular catheter.

Abstract: Rotating element catheters and catheter assemblies employ clutch assemblies for preventing rotational energy from being transmitted from a motor drive unit to the catheter element under defined circumstances. The catheter assembly includes an elongate member in which there is disposed a rotatable catheter drive cable. The catheter drive cable may have an operative element, e.g., an ultrasonic transducer or an artherctomy blade, distally mounted thereon for providing diagnostic or therapeutic functions to the physician. To control the rotation of the catheter drive shaft, the clutch assembly is configured such that the catheter drive shaft is operated in a drive mode (i.e., it is allowed to rotate) and in a release mode (i.e., it is prevented from rotating). The clutch assembly includes a driver member and a driven member, one of which is magnetic and the other of which is ferrous. The magnetic and ferrous members are arranged in relation to each other, e.g.

Abstract: A dynamically configurable ultrasound transducer element and related circuits and methods. The transducer may comprise an array of capacitive transducer elements, a row decoder coupled to said array of capacitive transducer elements, a column decoder coupled to said array of capacitive transducer elements, a bias voltage source coupled to said row decoder, and a driving signal source coupled to said column decoder. Preferably, a master clock also is provided to allow for a synchronization of signals between the row decoder and column decoder.

Abstract: A catheter assembly includes an elongate catheter body having a proximal end and a distal end with a drive cable disposed therein, the drive cable having a proximal end and a distal end, and rotatable relative to the catheter body. A first electromagnetic element is disposed proximate the distal end of the catheter, and a second electro-magnetic element disposed proximate the distal end of the drive cable and in electrical communication with an operative element mounted at the end of the drive cable, the first and second electromagnetic elements forming an inductive coupler. The catheter assembly can include various other distal operative elements, which are in communication with corresponding proximal operative elements via transmission lines embedded within the wall of the catheter body.

Abstract: Rotating element catheters and catheter assemblies employ clutch assemblies for preventing rotational energy from being transmitted from a motor drive unit to the catheter element under defined circumstances. The catheter assembly includes an elongate member in which there is disposed a rotatable catheter drive cable. The catheter drive cable may have an operative element, e.g., an ultrasonic transducer or an artherectomy blade, distally mounted thereon for providing diagnostic or therapeutic functions to the physician. To control the rotation of the catheter drive shaft, the clutch assembly is configured such that the catheter drive shaft is operated in a drive mode (i.e., it is allowed to rotate) and in a release mode (i.e., it is prevented from rotating).

Abstract: Rotating element catheters and catheter assemblies employ clutch assemblies for preventing rotational energy from being transmitted from a motor drive unit to the catheter element under defined circumstances. The catheter assembly includes an elongate member in which there is disposed a rotatable catheter drive cable. The catheter drive cable may have an operative element, e.g., an ultrasonic transducer or an artherectomy blade, distally mounted thereon for providing diagnostic or therapeutic functions to the physician. To control the rotation of the catheter drive shaft, the clutch assembly is configured such that the catheter drive shaft is operated in a drive mode (i.e., it is allowed to rotate) and in a release mode (i.e., it is prevented from rotating).

Abstract: A method and apparatus for solidifying inflamed and unstable plaque on the interior of a blood vessel including inserting a catheter assembly into a human blood vessel while the assembly is in a first, collapsed configuration, advancing the catheter assembly through the blood vessel, stopping at predetermined intervals and expanding the catheter assembly to a second, expanded configuration such that a plurality of temperature detectors contact the interior wall of the blood vessel. The areas of increased temperature are indicative of inflamed and unstable plaque, which is to be stabilized using at least one multi-temperature device, such as a Peltier device, to solidify the plaque and reduce the possibility of a myocardial infarction.

Abstract: Rotating element catheters and catheter assemblies employ clutch assemblies for preventing rotational energy from being transmitted from a motor drive unit to the catheter element under defined circumstances. The catheter assembly includes an elongate member in which there is disposed a rotatable catheter drive cable. The catheter drive cable may have an operative element, e.g., an ultrasonic transducer or an artherectomy blade, distally mounted thereon for providing diagnostic or therapeutic functions to the physician. To control the rotation of the catheter drive shaft, the clutch assembly is configured such that the catheter drive shaft is operated in a drive mode (i.e., it is allowed to rotate) and in a release mode (i.e., it is prevented from rotating). The clutch assembly includes a driver member comprising a first cylindrical body, and a driven member comprising a second cylindrical body in a concentric relationship with the first cylindrical body.

Abstract: A catheter assembly includes an elongate catheter body having a proximal end and a distal end with a drive cable disposed therein, the drive cable having a proximal end and a distal end, and rotatable relative to the catheter body. A first electro-magnetic element is disposed proximate the distal end of the catheter, and a second electro-magnetic element disposed proximate the distal end of the drive cable and in electrical communication with an operative element mounted at the end of the drive cable, the first and second electro-magnetic elements forming an inductive coupler. The catheter assembly can include various other distal operative elements, which are in communication with corresponding proximal operative elements via transmission lines embedded within the wall of the catheter body.

Abstract: The present invention provides ultrasound imaging catheters, systems and methods for their use which will be particularly useful to monitor the positioning of ablation catheters. In one embodiment, an imaging catheter (10) includes a catheter body (11) having a distal end (12), a proximal end (14) and a longitudinal axis (16). A transducer (20) is rotatably coupled to the distal end. The transducer has an axis of rotation (24) that is at a non-zero angle relative to the catheter body longitudinal axis. Such a configuration provides an exemplary side-looking imaging catheter.

Abstract: Rotating element catheters and catheter assemblies employ clutch assemblies for preventing rotational energy from being transmitted from a motor drive unit to the catheter element under defined circumstances. The catheter assembly includes an elongate member in which there is disposed a rotatable catheter drive cable. The catheter drive cable may have an operative element, e.g., an ultrasonic transducer or an artherectomy blade, distally mounted thereon for providing diagnostic or therapeutic functions to the physician. To control the rotation of the catheter drive shaft, the clutch assembly is configured such that the catheter drive shaft is operated in a drive mode (i.e., it is allowed to rotate) and in a release mode (i.e., it is prevented from rotating).

Abstract: The present invention provides exemplary ultrasound lucent apparatus and methods for use in a wide range of invasive imaging and surgical procedures. In one exemplary embodiment, an apparatus (10) comprises an elongate wire body (12) having an outer surface and a longitudinal axis (18). The wire body includes a plurality of corner reflectors (22) disposed on an embossed portion (20) of the outer surface. The wire body is adapted to be inserted into a body lumen or a patient vasculature. In this manner, use of corner reflector technology enhances the ultrasound reflective nature to increase the acoustical reflectivity of the wire body.

Abstract: A catheter assembly includes an elongate catheter body having a proximal end and a distal end with a drive cable disposed therein, the drive cable having a proximal end and a distal end, and rotatable relative to the catheter body. A first electro-magnetic element is disposed proximate the distal end of the catheter, and a second electro-magnetic element disposed proximate the distal end of the drive cable and in electrical communication with an operative element mounted at the end of the drive cable, the first and second electro-magnetic elements forming an inductive coupler. The catheter assembly can include various other distal operative elements, which are in communication with corresponding proximal operative elements via transmission lines embedded within the wall of the catheter body.