Patents by Inventor Donald Shaffer

Donald Shaffer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20230383298
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: January 3, 2023
    Publication date: November 30, 2023
    Applicants: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and compositions for reducing immunosuppression by tumor cells
    Patent number: 11597934
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: March 7, 2023
    Assignees: DANA FARBER CANCER INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20210139914
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: November 24, 2020
    Publication date: May 13, 2021
    Applicants: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and compositions for reducing immunosupression by tumor cells
    Patent number: 10876120
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: December 29, 2020
    Assignees: DANA-FARBER CANCER INSTITUTE, INC, THE GENERAL HOSPITAL CORPORATION
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Crank-less motion converter
    Patent number: 10156287
    Abstract: The invention is an apparatus to convert bidirectional rotary motion to unidirectional rotary motion having better mechanical advantage than a simple crank. It can make pedaling a bicycle easier or give an engine better mechanical advantage. It can also convert unidirectional rotary motion to bidirectional rotary motion, or continuous rotary motion to rotary motion with a momentary dwell. Each of these applications have input and output shafts on a common axis.
    Type: Grant
    Filed: September 2, 2013
    Date of Patent: December 18, 2018
    Inventor: Donald Shaffer
  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20180327750
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: April 3, 2018
    Publication date: November 15, 2018
    Applicants: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and compositions for reducing immunosupression by tumor cells
    Patent number: 9944931
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: April 17, 2018
    Assignees: Dana-Farber Cancer Institute, Inc., The General Hospital Corporation
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • Methods and Compositions for Reducing Immunosupression by Tumor Cells
    Publication number: 20160122766
    Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
    Type: Application
    Filed: June 10, 2014
    Publication date: May 5, 2016
    Inventors: Kai W. Wucherpfennig, Glenn Dranoff, Penghui Zhou, Donald Shaffer, Nir Hacohen, Harvey I. Cantor, Diana Alvarez Arias
  • CRANK-LESS MOTION CONVERTER
    Publication number: 20150211611
    Abstract: The invention is a crank-less motion converter to convert bidirectional rotary motion from a pendulum type engine to unidirectional rotary motion having good mechanical advantage throughout the power strokes. It uses two hypocycloid or Cardan style planetary gear sets. Gear-less versions can also be designed using linear bearings rather than tooth mesh to cause the motion. It can also convert unidirectional rotary motion to bidirectional rotary motion, or continuous rotary motion to rotary motion with a momentary dwell.
    Type: Application
    Filed: September 2, 2013
    Publication date: July 30, 2015
    Inventor: Donald SHAFFER
  • PC card adapter
    Patent number: D607885
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: January 12, 2010
    Assignee: Kyocera Corporation
    Inventors: Kazuyoshi R. Otani, Donald Shaffer, Kotaro Matsuo, Peter On, Joseph Zueck