Abstract: Etoposide glycosides and methods of making etoposide glycosides are disclosed. Glycosyl transferases catalyze addition of one or more monosaccharides to etoposide to yield etoposide glycosides. Suitable monosaccharides can be in the L- or D-configuration and typically have 5, 6, or 7 carbons. Suitable monosaccharides include allose, apiose, arabinose, fructose, fucitol, fucose, galactose, glucose, glucuronic acid, mannose, A-acetylglucosamine, rhamnose, or xylose. Uridine diphosphate glycosyl transferases can catalyze formation of either an alpha or beta glycosidic bond.

Abstract: Enasidenib glycosides and methods of making enasidenib glycosides are disclosed. Glycosyl transferases catalyze addition of one or more monosaccharides to enasidenib to yield enasidenib glycosides. Suitable monosaccharides can be in the L- or D-configuration and typically have 5, 6, or 7 carbons. Suitable monosaccharides include allose, apiose, arabinose, fructose, fucitol, fucose, galactose, galacturonate, glucose, glucuronic acid, mannose, N-acetylglucosamine, rhamnose, or xylose. Uridine diphosphate glycosyl transferases can catalyze formation of either an alpha or beta glycosidic bond.

Abstract: Ivacaftor glycosides and methods of making ivacaftor glycosides are disclosed. Glycosyl transferases catalyze addition of one or more monosaccharides to ivacaftor to yield ivacaftor glycosides. Suitable monosaccharides can be in the L- or D-configuration and typically have 5, 6, or 7 carbons. Suitable monosaccharides include allose, apiose, arabinose, fructose, fucitol, fucose, galactose, glucose, glucuronic acid, mannose, A-acetylglucosamine, rhamnose, or xylose. Uridine diphosphate glycosyl transferases can catalyze formation of either an alpha or beta glycosidic bond.

Abstract: Examples are disclosed that relate to methods, computing devices, and head-mounted display (HMD) devices for regulating a surface temperature of a device. In one example, a method comprises determining the surface temperature of a surface of the device, determining an energy accumulator value indicating cumulative energy received by a user via the surface of the device, and using a dynamic temperature limit function to calculate a temperature limit as a function of the energy accumulator value. The method also comprises comparing the surface temperature to the temperature limit. When the surface temperature has not reached the temperature limit, the method comprises incrementing the energy accumulator value. When the surface temperature has reached the temperature limit, the method comprises initiating a thermal mitigation action to cool the surface.

Abstract: Examples are disclosed that relate to methods, computing devices, and head-mounted display (HMD) devices for regulating a surface temperature of a device. In one example, a method comprises determining the surface temperature of a surface of the device, determining an energy accumulator value indicating cumulative energy received by a user via the surface of the device, and using a dynamic temperature limit function to calculate a temperature limit as a function of the energy accumulator value. The method also comprises comparing the surface temperature to the temperature limit. When the surface temperature has not reached the temperature limit, the method comprises incrementing the energy accumulator value. When the surface temperature has reached the temperature limit, the method comprises initiating a thermal mitigation action to cool the surface.

Abstract: In one aspect, the present invention comprises a method for providing stability of price to an asset. A preferred embodiment comprises: (a) a cryptocurrency; (b) an investment account; (c) a mode of redemption; (d) a computer network; (e) a company account; (f) a cryptocurrency exchange; (g) a processing application; (h) a method of destroying a cryptocurrency; (i) a method of funding an investment account; (j) a method of investing funds in an investment account.

Abstract: The invention relates a body fin for aiding in maneuvering a swimmer through water. The body fin comprises an upper body member adapted to be attached around sections of a human forearm, upper arm, shoulder, back and waist. The body fin also includes a lower body member that can be attached around a human waist, thigh, and ankle. The lower body fin includes a flexible fin having a first area contoured with a front side of the waist, thigh, and ankle and a second area extending away from the first section and the surface of the thighs and ankle. The upper body member also includes a first flexible fin extending from the surface of the forearm and a second flexible fin extending from the surface of the upper arm, shoulder, and waist, the ends of the first flexible fin terminating substantially at the surface of the sections.

Abstract: An ultrasound catheter is described herein for insertion into a cavity such as a blood vessel to facilitate imaging within a vasculature. The catheter comprises an elongate flexible shaft, a capacitive microfabricated ultrasonic transducer, and a sonic reflector. The elongate flexible shaft has a proximate end and a distal end. A capacitive microfabricated ultrasonic transducer (cMUT) is mounted to the shaft near the distal end. The reflector is positioned such that a reflective surface redirects ultrasonic waves to and from the transducer. In other embodiments, the catheter comprises a plurality of cMUT elements and operates without the use of reflectors. In further embodiments, integrated circuitry is incorporated into the design.

Abstract: A sensor element that may include a contamination-resistant coating on at least a portion thereof. The coating may include gamma alumina and a high temperature binder such as magnesium titanate. A sensor element that may include a contamination-resistant coating on at least a portion thereof. The coating may include gamma alumina, a high temperature binder such as magnesium titanate, and boehmite alumina. A method of making a contamination-resistant sensor element that may include mixing gamma alumina and a high temperature binder such as magnesium titanate to form a mixture, applying the mixture to at least a portion of a sensor element, and temperature treating the mixture to form a contamination-resistant coating on the sensor element.

Abstract: An ultrasound catheter is described herein for insertion into a cavity such as a blood vessel to facilitate imaging within a vasculature. The catheter comprises an elongate flexible shaft, a capacitive microfabricated ultrasonic transducer, and a sonic reflector. The elongate flexible shaft has a proximate end and a distal end. A capacitive microfabricated ultrasonic transducer (cMUT) is mounted to the shaft near the distal end. The reflector is positioned such that a reflective surface redirects ultrasonic waves to and from the transducer. In other embodiments, the catheter comprises a plurality of cMUT elements and operates without the use of reflectors. In further embodiments, integrated circuitry is incorporated into the design.

Abstract: An ultrasound catheter is described herein for insertion into a cavity such as a blood vessel to facilitate imaging within a vasculature. The catheter comprises an elongate flexible shaft, a capacitive microfabricated ultrasonic transducer, and a sonic reflector. The elongate flexible shaft has a proximate end and a distal end. A capacitive microfabricated ultrasonic transducer (cMUT) is mounted to the shaft near the distal end. The reflector is positioned such that a reflective surface redirects ultrasonic waves to and from the transducer. In other embodiments, the catheter comprises a plurality of cMUT elements and operates without the use of reflectors. In further embodiments, integrated circuitry is incorporated into the design.

Abstract: An ultrasound catheter is described herein for insertion into a cavity such as a blood vessel to facilitate imaging within a vasculature. The catheter comprises an elongate flexible shaft, a capacitive microfabricated ultrasonic transducer, and a sonic reflector. The elongate flexible shaft has a proximate end and a distal end. A capacitive microfabricated ultrasonic transducer (cMUT) is mounted to the shaft near the distal end. The reflector is positioned such that a reflective surface redirects ultrasonic waves to and from the transducer. In other embodiments, the catheter comprises a plurality of cMUT elements and operates without the use of reflectors. In further embodiments, integrated circuitry is incorporated into the design.

Abstract: An ultrasound catheter is described herein for insertion into a cavity such as a blood vessel to facilitate imaging within a vasculature. The catheter comprises an elongate flexible shaft, a capacitive microfabricated ultrasonic transducer, and a sonic reflector. The elongate flexible shaft has a proximate end and a distal end. A capacitive microfabricated ultrasonic transducer (cMUT) is mounted to the shaft near the distal end. The reflector is positioned such that a reflective surface redirects ultrasonic waves to and from the transducer. In other embodiments, the catheter comprises a plurality of cMUT elements and operates without the use of reflectors. In further embodiments, integrated circuitry is incorporated into the design.

Abstract: A toy storage and transportation apparatus includes a mat and a container that merges integrally into the mat. The container defines a storage interior and has a first open end and second closed end. The mat extends outwardly from the container to form a recreation area. When in a storage configuration, the mat flexibly rolls around and conforms to the shape of the container. The mat can further comprise a floor portion and at least two flap portions, with flap portions defining a crease with the floor portion. Each flap portion has an attachment fixed to the flap portion opposite from the crease. When folded along the creases and attached to each other with the attachment, the floor portion and flap portions define a tent structure. The flap portions can be formed with a sleeve, and support members are inserted into respective sleeves to form the tent structure.

Abstract: A contamination-resistant sensor element and methods for making the same are provided. A sensor element may include a contamination-resistant coating on at least a portion thereof. The coating may comprise gamma-delta alumina and lithium oxide and may have a thickness of about 100 to about 600 microns and a porosity of about 20 to about 70 percent. The method may include using gamma-delta alumina and lithium oxide to form a mixture, applying the mixture to at least a portion of a sensor element, and temperature treated the mixture to form a contamination-resistant coating on the surface of the measuring cell.

Abstract: A sensor element that may include a contamination-resistant coating on at least a portion thereof. The coating may include gamma alumina and a high temperature binder such as magnesium titanate. A sensor element that may include a contamination-resistant coating on at least a portion thereof. The coating may include gamma alumina, a high temperature binder such as magnesium titanate, and boehmite alumina. A method of making a contamination-resistant sensor element that may include mixing gamma alumina and a high temperature binder such as magnesium titanate to form a mixture, applying the mixture to at least a portion of a sensor element, and temperature treating the mixture to form a contamination-resistant coating on the sensor element.

Abstract: A contamination-resistant sensor element and methods for making the same are provided. A sensor element may include a contamination-resistant coating on at least a portion thereof. The coating may comprise gamma-delta alumina and lithium oxide and may have a thickness of about 100 to about 600 microns and a porosity of about 20 to about 70 percent. The method may include using gamma-delta alumina and lithium oxide to form a mixture, applying the mixture to at least a portion of a sensor element, and temperature treated the mixture to form a contamination-resistant coating on the surface of the measuring cell.

Abstract: A contamination-resistant sensor element and methods for making the same are provided. A sensor element may include a contamination-resistant coating on at least a portion thereof. The coating may comprise gamma-delta alumina and lithium oxide and may have a thickness of about 100 to about 600 microns and a porosity of about 20 to about 70 percent. The method may include using gamma-delta alumina and lithium oxide to form a mixture, applying the mixture to at least a portion of a sensor element, and temperature treated the mixture to form a contamination-resistant coating on the surface of the measuring cell.

Abstract: A base plate for a belt-driven cartridge for recording tape includes a molded or cast base layer with integral mounting bosses and ribs on the upper surface of the base layer for rigidly supporting axles and tape guides in precise perpendicular alignment and selected elevations relative to the lower reference surface of the base layer. The integral ribs extend between raised bosses to enhance torsional and flexural and depressional rigidity of the base layer over the entire area within the peripheral boundaries thereof.