Abstract: The present invention is an apparatus, system and method for use of an offshore hose loading station comprising multiple modular reel assemblies that may be selectively configured to a frame attached to a ship and or vessel wherein the reel assemblies may be powered by one motor and engaged for rotation by one shaft and provides a jumper shaft for when a module is taken out of line.

Abstract: The present invention is an automatic cut and transfer coiler and spooler apparatus, system and method for use generally comprising a rotatable turret with two independently driven spindles thereon wherein the drives for the independent spindles are attached to the turret for selectively rotating the spindles about their own axis independently.

Abstract: The present invention provides for a structure and a mechanism by which by utilizing additive manufacturing processes electrical connections are created that connect the top and bottom of a block in a customizable pattern. Specifically connection points can be created on the surface of the block and route them to alternate locations transforming the original pattern to a smaller, larger, or alternate pattern.

Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.

Abstract: The present invention is an apparatus, system and method for a new and improved coiling head utilized in wrapping elongated materials, which may have a zero and or near zero gap between leaves thereby reducing and or elimination indentations in the coiled elongated materials.

Abstract: Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.

Abstract: The present invention is an apparatus, system and method for a new and improved coiling head utilized in wrapping elongated materials, which may have a zero and or near zero gap between leaves thereby reducing and or elimination indentations in the coiled elongated materials.

Abstract: The present invention is an apparatus, system and method for use of an offshore hose loading station comprising multiple modular reel assemblies that may be selectively configured to a frame attached to a ship and or vessel wherein the reel assemblies may be powered by one motor and engaged for rotation by one shaft and provides a jumper shaft for when a module is taken out of line.

Abstract: Wearable devices are described herein including at least two photodetectors and a mount configured to mount the at least two photodetectors to an external surface of a wearer. The at least two photodetectors are configured to detect alignment between the wearable device and a target on or in the body of the wearer (e.g., to detect the location of vasculature within the body of the wearer relative to the at least two photodetectors). Alignment of the at least two photodetectors relative to the target could enable detection of one or more physiological properties of the wearer. For example, the wearable device could include a sensor configured to detect a property of the target when the sensor is above the target, and alignment of the target relative to the at least two photodetectors could include the sensor being located above the target.

Abstract: The present invention is an apparatus, system and method for use of an offshore hose loading station comprising multiple modular reel assemblies that may be selectively configured to a frame attached to a ship and or vessel wherein the reel assemblies may be powered by one motor and engaged for rotation by one shaft and provides a jumper shaft for when a module is taken out of line.

Abstract: Wearable devices are described herein including at least two sensors configured to detect hemodynamic properties of a wearer. A first sensor is configured to detect a hemodynamic property of a portion of vasculature, where the operation of the first sensor is based on a hemodynamic property detected by a second sensor. A timing of operation, a value of one or more controlled operational parameters, a filter setting, or some other aspect of the operation of the first sensor could be controlled based on the hemodynamic property detected by the second sensor. Hemodynamic properties could include blood flow rate, volume, and/or pressure in one or more portions of vasculature, a timing, rate, delay, or other information about heartbeats, an oxygenation level of blood, a velocity of blood cells in blood, or some other information about a wearer's blood, heart, and/or cardiovascular system.

Abstract: Embodiments are directed towards managing data. Attributes of model fields of a plurality of model objects may be analyzed. If the analysis of the attributes discovers primary key fields in the model objects, the characteristics of the primary keys may be compared with the characteristics of other model objects. If affirmative results of the comparison indicate that one or more foreign key fields may be in the other model objects, one or more relationships that associate the primary key fields with the foreign key fields may be provided. And, a system model may be provided based on the relationships and the model objects that include the primary key fields and the model objects that include the foreign key fields.

Abstract: Optical measurement of physiological parameters with wearable devices often includes measuring signals in the presence of significant noise sources. These noise sources include, but are not limited to, noise associated with: variable optical coupling to skin or tissue, variations in tissue optical properties with time due to changes in humidity, temperature, hydration, variations in tissue optical properties between individuals, variable coupling of ambient light sources into detectors, and instrument and detector noise, including electrical noise, radio frequency or magnetic interference, or noise caused by mechanical movement of the detector or its components. The present disclosure includes devices and methods configured to produce representations of the raw data in which noise, broadly defined, is separated from the data of interest. The disclosed devices and methods may include subtracting or calibrating out these noise sources and other spurious fluctuations in wearable devices with optical sensors.

Abstract: Embodiments are directed towards managing data. An attributes engine may be employed to perform various actions, including: analyzing characteristics of model object features of a plurality of model objects; classifying the model object features based on the characteristics, such that the characteristics include a data type and values of the model object features; and associating similarity tasks with the model object features based on their classification. A similarity engine may then be employed to perform further actions, including: providing a similarity model that includes the similarity tasks; employing the similarity model to provide candidate similarity scores based on exemplar model objects labeled as being similar; modifying the similarity model based on the exemplar model objects and the candidate similarity scores; employing the modified similarity model to provide similarity scores for model objects based on the one or more similarity tasks.

Abstract: Optical measurement of physiological parameters with wearable devices often includes measuring signals in the presence of significant noise sources. These noise sources include, but are not limited to, noise associated with: variable optical coupling to skin or tissue, variations in tissue optical properties with time due to changes in humidity, temperature, hydration, variations in tissue optical properties between individuals, variable coupling of ambient light sources into detectors, and instrument and detector noise, including electrical noise, radio frequency or magnetic interference, or noise caused by mechanical movement of the detector or its components. The present disclosure includes devices and methods configured to produce representations of the raw data in which noise, broadly defined, is separated from the data of interest. The disclosed devices and methods may include subtracting or calibrating out these noise sources and other spurious fluctuations in wearable devices with optical sensors.

Abstract: Systems and methods are provided for detecting the flow of blood or other fluids in biological tissue by illuminating the biological tissue with two or more beams of coherent light and detecting responsively emitted light. A difference in wavelength, coherence length, beam divergence, or some other property of the beams of illumination causes the beams to preferentially scatter from, be absorbed by, or otherwise interact with respective elements of the biological tissue. Flow properties in one or more regions of the biological tissue (e.g., a region with which both beams of light preferentially interact, a region with which only one of the beams preferentially interacts) could be determined based on detected responsively emitted light from the biological tissue. Variations in speckle patterns over time and/or space, Doppler shifts, or some other properties of the detected light could be used to determine the flow properties.

Abstract: A system for measuring and/or monitoring an analyte present on the skin is provided. The system includes a substrate that may be attached to an external skin surface and a reader device. The substrate includes a sensor comprising aptamer conjugates and is configured to obtain one or more measurements related to at least one analyte in the perspiration or interstitial fluid. The reader device is configured to detect the analyte in the least one of perspiration or interstitial fluid via interaction with the substrate.

Abstract: A system for measuring and/or monitoring an analyte present in interstitial fluid in skin is provided. The system includes a substrate that may be implanted into the skin and a reader device. The substrate includes a sensor comprising aptamer conjugates and is configured to obtain one or more measurements related to at least one analyte in interstitial fluid. The reader device is configured to detect the analyte in interstitial fluid via interaction with the substrate.

Abstract: Embodiments are directed towards managing data. Attributes of model fields of a plurality of model objects may be analyzed. If the analysis of the attributes discovers primary key fields in the model objects, the characteristics of the primary keys may be compared with the characteristics of other model objects. If affirmative results of the comparison indicate that one or more foreign key fields may be in the other model objects, one or more relationships that associate the primary key fields with the foreign key fields may be provided. And, a system model may be provided based on the relationships and the model objects that include the primary key fields and the model objects that include the foreign key fields.

Abstract: Systems and methods are provided for detecting the depth, flow rate, and other properties of regions of blood flow in biological tissue by illuminating the biological tissue with beams of coherent light and detecting responsively emitted light. This includes detecting lights emitted from the tissue having a plurality of respective different exposure times. The relationship between the intensity of the received light and the exposure times is determined and used to determine the depth, flow velocity, or other properties of regions of flow within the biological tissue. This can include determining a spatial and/or temporal contrast of the received light intensity. Determining the depth of a region of flow can include comparing determined properties of light received from the tissue at two different polarizations. Determining the depth of a region of flow can include comparing determined properties of light received from the tissue at two different locations.