Abstract: This invention provides a purified new differentiation antigen, designated NDA4, associated with the growth and proliferation of activated B lymphocytes and characterized by a molecular weight of about 46,000 daltons.The invention also provides an antibody capable of specifically forming a complex with purified NDA4, and a hybridoma which produces a monoclonal antibody that specifically recognizes the isolated NDA4.The invention also pertains to a method for dectecting B cells or helper T cells, each of which has a B cell growth factor receptor, which comprises contacting a sample which contains B cells or helper T cells with substances capable of forming complexes with the B cell growth factor receptors so as to form cellular complexes between the substances and the B cell growth factor receptors, and detecting such cellular complexes.

Abstract: This invention provides a purified new differentiation antigen, designated NDA.sub.3, associated with the growth and proliferation of activated B lymphocytes and characterized by a molecular weight of about 36,000 daltons.The invention also provides an antibody capable of specifically forming a complex with purified NDA.sub.3. Another aspect of the invention provides a hybridoma which produces a monoclonal antibody that specifically recognizes the isolated NDA.sub.3.The invention also pertains to a method for detecting B cells or helper T cells, each of which has a B cell growth factor receptor, which comprises contacting a sample which contains B cells or helper T cells with substances capable of forming complexes with the B cell growth factor receptors so as to form cellular complexes between the substances and the B cell growth factor receptors, and detecting such cellular complexes.

Abstract: A late differentiation antigen (LDA.sub.1) expressed by activated helper cells is described. LDA.sub.1 is a membrane protein recognized by a monoclonal antibody produced by immunizing mice with an alloreactive human T cell clone with helper function. LDA.sub.1 is expressed by helper T cells optionally 9 days after activation. Anti-LDA.sub.1 monoclonal antibody blocks T cell enhancement of B-cell immunoglobulin production. Thus, LDA.sub.1 is associated with helper T cell effector function. Methods of diagnosis and therapy based upon LDA.sub.1 are also described.

Abstract: Late differentiation antigens (LDA.sub.1 and LDA.sub.2) expressed by activated helper cells are described. LDA.sub.1 and LDA.sub.2 are membrane proteins recognized by monoclonal antibodies produced by immunizing mice with alloreactive human T cell clones with helper function. LDA.sub.1 and LDA.sub.2 are expressed by helper T cells. LDA.sub.1 monoclonal antibody and LDA.sub.2 monoclonal antibody block T cell enhancement of B cell immunoglobulin production. Thus, LDA.sub.1 and LDA.sub.2 are associated with helper T cell effector function. Methods of diagnosis and therepy based upon LDA.sub.1 and LDA.sub.2 are also described.

Abstract: The invention relates to a process for the production of ethyl alcohol from citrus molasses fermentation in which improved yields of ethyl alcohol are obtained by preliminarily removing fermentation inhibiting agents, specifically oils, from the fermenter charge. The process may be carried out in batch or by continuous operation. The alcohol formed in the fermentation step is distilled off at about 190.degree. proof and the latter may then be dehydrated in a molecular sieve column to produce a product substantially free of water. Also a novel oil stripper is presented in order that the oils may be effectively and economically removed prior to fermentation.

Abstract: A seal between a metal surface and a surface of glass or glass-like ceramic having, in juxtaposition, the metal, gold, an indium-gold alloy, indium, and either glass or a glass-like ceramic.

Abstract: A method for making a glass-or ceramic-to-metal seal, and the seal itself. A layer of gold is deposited onto the metal. A thin layer of indium is placed over the gold, and the structure is heated above the melting point of indium to create a gold-indium alloy at the gold-indium interface. After cooling, the indium surface of the structure and the glass surface are super-cleaned. The super-cleaned surface are then pressed together to form an air-tight seal.