Patents by Inventor Donald W. Stoutamire

Donald W. Stoutamire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of optically active alpha-hydroxynitriles
    Patent number: 4723027
    Abstract: Preparation of certain optically-active alpha-hydroxynitriles or a mixture enriched therein comprises treating an aldehyde with hydrogen cyanide in a substantially water-immiscible, aprotic solvent in the presence of a cyclo(D-phenylalanyl-D-histidine) as a catalyst.
    Type: Grant
    Filed: January 27, 1986
    Date of Patent: February 2, 1988
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Donald W. Stoutamire, Walter Dong
  • Preparation of optically-active cyanomethyl esters
    Patent number: 4681947
    Abstract: Optically-active alpha-cyano esters are prepared by treating a non-symmetrical ketene with a racemic or an optically-active alpha-hydroxynitrile or with an aldehyde and cyanide ions in the presence of an optically-active amine catalyst.
    Type: Grant
    Filed: January 18, 1985
    Date of Patent: July 21, 1987
    Inventors: Donald W. Stoutamire, Charles H. Tieman
  • Increasing enantiomeric selectivity in chiral cyanohydrination
    Patent number: 4611077
    Abstract: Enantiomeric selectivity is increased in chiral cyanohydrination of an aromatic aldehyde using a chiral cyclo(phenylalanylhistidine) catalyst by treating the (recycle) aldehyde to remove catalyst poisons or impurities which adversely effect enantiomeric selectivity.
    Type: Grant
    Filed: June 26, 1985
    Date of Patent: September 9, 1986
    Assignee: Shell Oil Company
    Inventors: Walter Dong, Donald W. Stoutamire
  • Preparation of optically active alpha-hydroxynitriles
    Patent number: 4594196
    Abstract: Preparation of certain optically-active alpha-hydroxynitriles or a mixture enriched therein comprises treating an aldehyde with hydrogen cyanide in a substantially water-immiscible, aprotic solvent in the presence of a cyclo(D-phenylalanyl-D-histidine) as a catalyst.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: June 10, 1986
    Assignee: Shell Oil Company
    Inventors: Donald W. Stoutamire, Walter Dong
  • Preparation of cyanomethyl esters
    Patent number: 4582646
    Abstract: Stereoisomerically-enriched cyanomethyl esters are prepared by treating a non-symmetrical ketene with a racemic or optically-active alpha-hydroxynitrile in the absence of a catalyst or in the presence of an achiral tertiary amine catalyst.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: April 15, 1986
    Assignee: Shell Oil Company
    Inventors: Donald W. Stoutamire, Charles H. Tieman
  • Preparation of optically-active (mixed) anhydrides and acids
    Patent number: 4570017
    Abstract: A process for the preparation of an optically-active (mixed) anhydride of an alpha-chiral (optically-active) carboxylic acid by treating a non-symmetrical ketene with a carboxylic acid in the presence of an optically-active (chiral) tertiary amine catalyst. Hydrolysis of the resulting (mixed) anhydride yields the optically-active acid corresponding to the non-symmetrical ketene.
    Type: Grant
    Filed: March 26, 1984
    Date of Patent: February 11, 1986
    Assignee: Shell Oil Company
    Inventor: Donald W. Stoutamire
  • Preparation of optically-active cyanomethyl esters
    Patent number: 4560515
    Abstract: Optically-active alpha-cyano esters are prepared by treating a non-symmetrical ketene with a racemic or an optically-active alpha-hydroxynitrile or with an aldehyde and cyanide ions in the presence of an optically-active amine catalyst.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: December 24, 1985
    Assignee: Shell Oil Company
    Inventors: Donald W. Stoutamire, Charles H. Tieman
  • Asymmetric synthesis of esters and acids
    Patent number: 4546198
    Abstract: Stereoisomerically-enriched esters are prepared by treating a non-symmetrical ketene with a racemic or chiral tertiary-base-substituted alkylcarbinol. Optional hydrolysis of the esters gives the corresponding optically-active carboxylic acids corresponding to the non-symmetrical ketene.
    Type: Grant
    Filed: March 26, 1984
    Date of Patent: October 8, 1985
    Assignee: Shell Oil Company
    Inventor: Donald W. Stoutamire
  • Preparation of optically-active alpha-substituted carboxylic esters and acids
    Patent number: 4529810
    Abstract: Optically-active alpha-substituted carboxylic esters are prepared by treating a non-symmetrical ketene with an alcohol in the presence of an optically-active amine catalyst. Hydrolysis of the resulting esters, yields the optically-active acid corresponding to the non-symmetrical ketene.
    Type: Grant
    Filed: January 6, 1984
    Date of Patent: July 16, 1985
    Assignee: Shell Oil Company
    Inventor: Donald W. Stoutamire
  • Pesticidal .alpha.-cyanobenzyl ester enantiomer pair
    Patent number: 4176195
    Abstract: An enantiomer pair consisting of S-.alpha.-cyano-3-phenoxybenzyl S-.alpha.-isopropyl-p-chlorophenylacetate and R-.alpha.-cyano-3-phenoxybenzyl R-.alpha.-isopropyl-p-chlorophenylacetate, said pair substantially free of other stereoisomers is a highly active pesticide.
    Type: Grant
    Filed: July 20, 1978
    Date of Patent: November 27, 1979
    Assignee: Sumitomo Chemical Company, Limited
    Inventor: Donald W. Stoutamire