Patents by Inventor Donald Wiesler

Donald Wiesler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagents for detection of primary amines
    Patent number: 5631374
    Abstract: The present invention is directed to derivatives of aroyl-2-quinoline-carboxaldehyde and their use in detection and quantification of minute amounts of primary amines.
    Type: Grant
    Filed: October 28, 1993
    Date of Patent: May 20, 1997
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Milos V. Novotny, Donald Wiesler, Jinping Liu, You-Zung Hsieh
  • Quinoline-2-(carboxaldehyde) reagents for detection of primary amines
    Patent number: 5459272
    Abstract: The present invention is directed to derivatives of aroyl-2-quinoline-carboxaldehyde and their use in detection and quantification of minute amounts of primary amines.
    Type: Grant
    Filed: October 16, 1990
    Date of Patent: October 17, 1995
    Assignee: Research Corporation Technologies
    Inventors: Milos V. Novotny, Donald Wiesler, Jinping Liu, You-Zung Hsieh
  • Fluorogenic reagents for detection of glycoconjugates, .alpha.-ketoacids and diketones
    Patent number: 5310682
    Abstract: Compounds containing .alpha.-discarbonyl groups are rendered capable of fluorescent emission by conjugation with carboxylic acid-terminated ortho-diaminoaryl reagents. The carboxylic acid groups serve as ionizable moieties which facilitate the conjugation reaction, and are retained in the conjugation product to enable, or enhance the ability of, the conjugated compounds to be separated in chromatographic and electromigration separation processes, notably electrophoresis. Ortho-dinitro derivatives of the reagents are also disclosed, these derivatives offering the advantage of stability as well as the ability to be used directly in the reaction in the presence of a reducing agent.
    Type: Grant
    Filed: June 17, 1992
    Date of Patent: May 10, 1994
    Assignee: Indiana University Foundation
    Inventors: Milos V. Novotny, Osamu Shirota, Donald Wiesler