Patents by Inventor Donata Dei

Donata Dei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10730890
    Abstract: There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: August 4, 2020
    Assignee: MOLTENI THERAPEUTICS S.R.L.
    Inventors: Gabrio Roncucci, Donata Dei, Giacomo Chiti, Daniele Nistri
  • Publication number: 20170073358
    Abstract: There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.
    Type: Application
    Filed: January 28, 2016
    Publication date: March 16, 2017
    Inventors: Gabrio RONCUCCI, Donata DEI, Giacomo CHITI, Daniele NISTRI
  • Publication number: 20140163218
    Abstract: There are described phthalocyanine derivates, the pharmaceutical compositions and the medical devices that contain them, possibly in combination with chelating agents, such as EDTA, useful for treating, by means of photodynamic therapy, diseases characterised by cellular hyperproliferation, microbial infections caused by Gram? bacteria, Gram+ bacteria and fungi, and for treating various types of infected and non-infected ulcers.
    Type: Application
    Filed: August 6, 2012
    Publication date: June 12, 2014
    Applicant: MOLTENI THERAPEUTICS S.R.L.
    Inventors: Donata Dei, Gabrio Roncucci, Gianluca Soldaini, Daniele Nistri, Giacomo Chiti, Moira Municchi, Lia Fantetti, Francesco Giuliani
  • Patent number: 8741264
    Abstract: Self-sterilising products, and in particular novel products comprising phthalocyanine derivatives bound to polymers, a process for the preparation of said products and their use for preparing self-sterilising industrial and medical articles or devices, are described.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: June 3, 2014
    Assignee: Molteni Therapeutics S.R.L.
    Inventors: Gabrio Roncucci, Lia Fantetti, Giacomo Chiti, Donata Dei, Carmela Alongi, Annalisa Cocchi, Valentina Paschetta
  • Patent number: 8664382
    Abstract: The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivolex vivo applications, such as blood and blood derivatives sterilization.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: March 4, 2014
    Assignee: Molteni Therapeutics S.r.l.
    Inventors: Gabrio Roncucci, Donata Dei, Giacomo Chiti, Lia Fantetti, Francesco Giuliani, Giulio Jori, Gian Maria Rossolini
  • Patent number: 8288528
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: October 16, 2012
    Assignee: L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • Patent number: 8242262
    Abstract: A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitizing agents in photodynamic therapy.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: August 14, 2012
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'di Esercizio S.p.A.
    Inventors: Donata Dei, Giacomo Chiti, Daniele Nistri, Gabrio Roncucci, Aldo Hendrikus Velders, Salvatore Demartis, Valentina Paschetta
  • Publication number: 20120135972
    Abstract: There is described a phthalocyanine derivative of formula (I) consisting of 4 isomers wherein the relative isomer B content is less than or equal to 1% by weight.
    Type: Application
    Filed: July 30, 2010
    Publication date: May 31, 2012
    Inventors: Gabrio Roncucci, Donata Dei, Giacomo Chiti, Daniele Nistri
  • Patent number: 8067404
    Abstract: Phthalocyanine derivatives are described having photosensitizing characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: November 29, 2011
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Giacomo Chiti, Donata Dei, Annalisa Cocchi, Lia Fantetti, Stefano Mascheroni
  • Patent number: 7947674
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: May 24, 2011
    Assignee: L. Molteni & C. Dei Fratelli Alitti
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • Publication number: 20110112464
    Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitising agents, in particular in photodynamic therapy, are herein described.
    Type: Application
    Filed: January 14, 2011
    Publication date: May 12, 2011
    Applicant: L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.P.A.
    Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
  • Patent number: 7915248
    Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.
    Type: Grant
    Filed: September 10, 2005
    Date of Patent: March 29, 2011
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'Di Esercizio S.p.A
    Inventors: Donata Dei, Gabrio Roncucci, Daniele Nistri, Yann Raoul, Giacomo Chiti, Moira Municchi, Giulio Jori
  • Patent number: 7842682
    Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: November 30, 2010
    Assignee: L. Molteni & C. Dei Fratelli Alitti
    Inventors: Gabrio Roncucci, Giulio Jori, Francesca Giuntini, Clara Fabris, Giacomo Chiti, Moira Municchi, Donata Dei
  • Patent number: 7749991
    Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: July 6, 2010
    Assignee: L. Molteni & C. Dei Fratelli Alitti-Societa di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Lia Fantetti, Maria Paola De Filippis, Donata Dei, Giulio Jori
  • Publication number: 20090131393
    Abstract: A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitising agents in photodynamic therapy.
    Type: Application
    Filed: May 4, 2006
    Publication date: May 21, 2009
    Applicant: L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A.
    Inventors: Donata Dei, Giacomo Chiti, Daniele Nistri, Gabrio Roncucci, Aldo Hendrikus Velders, Salvatore Demartis, Valentina Paschetta
  • Publication number: 20090130049
    Abstract: Self-sterilising products, and in particular novel products comprising phthalocyanine derivatives bound to polymers, a process for the preparation of said products and their use for preparing self-sterilising industrial and medical articles or devices, are described.
    Type: Application
    Filed: June 29, 2006
    Publication date: May 21, 2009
    Applicant: L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A.
    Inventors: Gabrio Roncucci, Lia Fantetti, Giacomo Chiti, Donata Dei, Carmela Alongi, Annalisa Cocchi, Valentina Paschetta
  • Publication number: 20090131392
    Abstract: Phthalocyanine derivatives are described having photosensitising characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria.
    Type: Application
    Filed: May 4, 2006
    Publication date: May 21, 2009
    Applicant: L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A.
    Inventors: Gabrio Roncucci, Giacomo Chiti, Donata Dei, Annalisa Cocchi, Lia Fantetti, Stefano Mascheroni
  • Publication number: 20080009464
    Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.
    Type: Application
    Filed: March 11, 2004
    Publication date: January 10, 2008
    Applicant: L. Molteni & C. dei Fratelli Alitti Societa di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Giulio Jori, Francesca Giuntini, Clara Fabris, Giacomo Chiti, Moira Municchi, Donata Dei
  • Publication number: 20080004239
    Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.
    Type: Application
    Filed: September 10, 2005
    Publication date: January 3, 2008
    Inventors: Donata Dei, Gabrio Roncucci, Daniele Nistri, Yann Raoul, Giacomo Chiti, Moira Municchi, Giulio Jori
  • Patent number: 7265100
    Abstract: The present invention refers to a process for the separation of regioisomeric mixtures of metal phthalocyanines of formula (I), to the regioisomers obtained by this process, and their use as phototherapeutic and photodiagnostic agents
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: September 4, 2007
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa' di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Francesca Giuntini, Donata Dei, Maria Paola De Filippis, Paolo Sarri, Marco Possenti, Valentina Paschetta, Giacomo Chiti