Patents by Inventor Donato Altomare

Donato Altomare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the diagnosis of a carcinoma and uses thereof
    Patent number: 9347953
    Abstract: The present invention relates to a method for diagnosing a carcinoma or a residual disease associated thereto, or for the prognosis of a carcinoma, or for monitoring the effectiveness of an anti-tumour therapy directed against a carcinoma, or for monitoring the follow-up of an individual affected by a carcinoma, in particular colorectal carcinoma, carcinoma of the stomach, mammary carcinoma, pulmonary carcinoma or carcinoma of the prostate, carcinoma of the liver, carcinoma of the ovary, carcinoma of the kidney, carcinoma of the thyroid, carcinoma of the bladder or carcinoma of the pancreas. The method of the invention consists in placing adult stem cells in contact with a sample of a haemo-derivative of the individual to be analyzed and in verifying the expression of at least an epithelial marker in the stem cells by means of immunofluorescence, immunohistochemistry, ELISA or RT-PCR.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: May 24, 2016
    Assignee: THD S.p.A.
    Inventors: Filippo Bastia, Donato Altomare, Alfredo Di Leo, Maria Teresa Rotelli, Michele Barone
  • METHOD FOR THE DIAGNOSIS OF A CARCINOMA AND USES THEREOF
    Publication number: 20130316361
    Abstract: The present invention relates to a method for diagnosing a carcinoma or a residual disease associated thereto, or for the prognosis of a carcinoma, or for monitoring the effectiveness of an anti-tumour therapy directed against a carcinoma, or for monitoring the follow-up of an individual affected by a carcinoma, in particular colorectal carcinoma, carcinoma of the stomach, mammary carcinoma, pulmonary carcinoma or carcinoma of the prostate, carcinoma of the liver, carcinoma of the ovary, carcinoma of the kidney, carcinoma of the thyroid, carcinoma of the bladder or carcinoma of the pancreas. The method of the invention consists in placing adult stem cells in contact with a sample of a haemo-derivative of the individual to be analysed and in verifying the expression of at least an epithelial marker in the stem cells by means of immunofluorescence, immunohistochemistry, ELISA or RT-PCR.
    Type: Application
    Filed: December 6, 2010
    Publication date: November 28, 2013
    Applicant: THD S.P.A.
    Inventors: Filippo Bastia, Donato Altomare, Alfredo Di Leo, Maria Teresa Rotelli, Michele Barone