Patents by Inventor Doncho Uzunov

Doncho Uzunov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to identify modulators for human 3alpha-hydroxysteroid dehydrogenase
    Publication number: 20090171639
    Abstract: 3 ?-hydroxysteroid dehydrogenase (3?-HSD) plays a central role in the metabolism and action of steroid hormones and neurosteroids (steroids synthesized in the central nervous system). The high resolution structure of human type III 3?-HSD crystallized in complex with cofactor NADP is determined by X-ray diffraction. Furthermore the active site is determined. The structure coordinates of the enzyme may be used to design and select novel classes of modulators to human type III 3?-HSD.
    Type: Application
    Filed: June 26, 2007
    Publication date: July 2, 2009
    Inventors: Philipp Floersheim, Christian Ostermeier, Doncho Uzunov, Wolfgang Jahnke
  • Method to identify modulators for human 3alpha-hydroxysteroid dehydrogenase
    Publication number: 20050202505
    Abstract: 3 ?-hydroxysteroid dehydrogenase (3a-HSD) plays a central role in the metabolism and action of steroid hormones and neurosteroids (steroids synthesized in the central nervous system). The high resolution structure of human type III 3a-HSD crystallized in complex with cofactor NADP is determined by X-ray diffraction. Furthermore the active site is determined. The structure coordinates of the enzyme may be used to design and select novel classes of modulators to human type III 3a-HSD.
    Type: Application
    Filed: August 21, 2002
    Publication date: September 15, 2005
    Inventors: Philipp Floersheim, Christian Ostermeier, Doncho Uzunov, Wolfgang Jahnke