Abstract: Disclosed is a polypeptide containing an extracellular domain of a synaptogenic protein, and a method for manufacturing a nerve cell, a complex containing a biotin tagged at the C-terminus of the polypeptide, an artificial synapse inducer for coupling the composite to a streptavidin (SAV)-coated substrate and a nerve cell. The complex tagged with a biotin at the C-terminus of the polypeptide containing the extracellular domain of the synaptogenic protein, such as neuroligin-1, can display activity by being attached to the SAV-coated substrate to adjust the orientation thereof without help of a supported lipid bilayer. The complex containing an additional RFP between the extracellular domain and the biotin of the synaptogenic protein not only facilitates easier mass-production, quantification, and tracking, but also displays activity of a normal synaptogenic protein, thereby inducing excitatory or inhibitory synaptic differentiation by being fixed to the substrate and added to the nerve cell culture.

Abstract: The disclosed computer-implemented method for automatically making selections in user interfaces may include (1) detecting, on a computing device, a user interface that comprises a prompt for a user of the computing device to select between a first option and a second option, (2) identifying a profile for making, on behalf of the user, a predetermined selection of one of the first option and the second option, (3) determining that the predetermined selection indicates that the first option should be selected on behalf of the user, and (4) selecting, from the prompt, the first option on behalf of the user. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention relates to a virus-microbead complex including a microbead and a virus layer, in which linear viruses are bound individually to the surface of the microbead, and an immunoassay kit including the same. The virus-microbead complex of the present invention is characterized in that the linear viruses are bound to the surface of the microbead so that the orientations of the linear viruses are regulated using the interaction of streptavidin-biotin introduced thereon, thereby providing a significantly increased volume to surface area ratio, increasing the number of antibodies or ligands capable of binding thereto, and as a result, mediating the binding of antibodies or ligands to a unit bead with high density, which eventually leads to an increased sensitivity in immunoassays, and an application into a suspension array.

Abstract: Provided are a method for forming a pattern, and a catalyst and an electronic element using the method. The method for forming a pattern comprises the steps of: preparing, on a surface, a substrate sequentially including a photoconductive material layer and an oxide layer; making an area, on which a pattern is to be formed, on the oxide layer of the substrate, come into contact with an electrolyte; connecting the substrate and the electrolyte to a first electrode and a second electrode connected to a power source, respectively; and selectively irradiating light from a light source to the electrolyte and applying a voltage to the first electrode or the second electrode, thereby directly forming the pattern on the oxide layer of the substrate.

Abstract: The present disclosure relates to a probe capable of electrochemical and Raman spectroscopic monitoring wherein a Raman-active gold microshell having conductivity is attached to the tip of a glass microcapillary tube in which a conductive material is coated on an inner wall thereof by electroless plating. By coupling the probe with a system capable of moving the probe, the activities of various catalyst materials can be detected quickly and information of intermediate products moving from and adsorbed on the surface can be provided.

Abstract: Disclosed is a polypeptide containing an extracellular domain of a synaptogenic protein, and a method for manufacturing a nerve cell, a complex containing a biotin tagged at the C-terminus of the polypeptide, an artificial synapse inducer for coupling the composite to a streptavidin (SAV)-coated substrate and a nerve cell. The complex tagged with a biotin at the C-terminus of the polypeptide containing the extracellular domain of the synaptogenic protein, such as neuroligin-1, can display activity by being attached to the SAV-coated substrate to adjust the orientation thereof without help of a supported lipid bilayer. The complex containing an additional RFP between the extracellular domain and the biotin of the synaptogenic protein not only facilitates easier mass-production, quantification, and tracking, but also displays activity of a normal synaptogenic protein, thereby inducing excitatory or inhibitory synaptic differentiation by being fixed to the substrate and added to the nerve cell culture.

Abstract: Provided are a method for forming a pattern, and a catalyst and an electronic element using the method. The method for forming a pattern comprises the steps of: preparing, on a surface, a substrate sequentially including a photoconductive material layer and an oxide layer; making an area, on which a pattern is to be formed, on the oxide layer of the substrate, come into contact with an electrolyte; connecting the substrate and the electrolyte to a first electrode and a second electrode connected to a power source, respectively; and selectively irradiating light from a light source to the electrolyte and applying a voltage to the first electrode or the second electrode, thereby directly forming the pattern on the oxide layer of the substrate.

Abstract: In a method of detecting an etch by-product, the method including forming a magnetic layer including palladium (Pd) on a substrate; etching the magnetic layer to form a magnetic layer pattern; depositing a mixture including an alkyl bromide compound on a surface of the magnetic layer pattern; and measuring a current difference between the substrate and the mixture to detect an etch by-product on the surface of the magnetic layer pattern.

Abstract: The present invention relates to a virus-microbead complex including a microbead and a virus layer, in which linear viruses are bound individually to the surface of the microbead, and an immunoassay kit including the same. The virus-microbead complex of the present invention is characterized in that the linear viruses are bound to the surface of the microbead so that the orientations of the linear viruses are regulated using the interaction of streptavidin-biotin introduced thereon, thereby providing a significantly increased volume to surface area ratio, increasing the number of antibodies or ligands capable of binding thereto, and as a result, mediating the binding of antibodies or ligands to a unit bead with high density, which eventually leads to an increased sensitivity in immunoassays, and an application into a suspension array.

Abstract: In a method of detecting an etch by-product, the method including forming a magnetic layer including palladium (Pd) on a substrate; etching the magnetic layer to form a magnetic layer pattern; depositing a mixture including an alkyl bromide compound on a surface of the magnetic layer pattern; and measuring a current difference between the substrate and the mixture to detect an etch by-product on the surface of the magnetic layer pattern.

Abstract: The present invention provides a fuel electrode including a substrate and a nanoporous metallic catalyst layer, characterized in that the metallic catalyst layer includes open interconnected 3D nanopores, and the pore and the pore connections have a size suitable for allowing hydrocarbons having alcohol groups to pass through the interconnected pores so that they react in contact with the surface of the catalyst by confined molecular dynamics. Further, the present invention provides a compartmentless fuel cell electrode pair including the fuel electrode of the present invention; and a polymer membrane-coated oxygen electrode into which a catalyst layer is introduced onto the substrate and which blocks the hydrocarbons having alcohol groups as a fuel molecule and allows the diffusion of oxygen molecules.

Abstract: The present disclosure relates to a probe capable of electrochemical and Raman spectroscopic monitoring wherein a Raman-active gold microshell having conductivity is attached to the tip of a glass microcapillary tube in which a conductive material is coated on an inner wall thereof by electroless plating. By coupling the probe with a system capable of moving the probe, the activities of various catalyst materials can be detected quickly and information of intermediate products moving from and adsorbed on the surface can be provided.

Abstract: A method for the fabrication of a mesoporous metal electrode in a non-liquid crystalline phase was tested. Specifically, there was tested the efficacy of the method for the fabrication of a mesoporous metal electrode which comprises forming the mesoporous metal electrode on a substrate by chemical or electrochemical reduction of a mixture comprising a solvent, a structure-directing agent, and a source of a metal, characterized in that the mixture is maintained in a non-liquid crystal phase. Furthermore, the usefulness of the mesoporous metal electrode thus prepared from the non-liquid crystalline phase was also tested. The mesoporous metal electrode prepared from the non-liquid crystalline phase had a large surface area, and a roughness factor thereof was controlled by charges passed during electroplating. The method made it possible to fabricate the mesoporous metal electrode in the non-liquid crystalline phase, even more flexible than a liquid crystalline phase.

Abstract: The present invention relates to a mesoporous platinum electrode for detecting biochemical substrate, comprising an electrode and a mesoporous platinum layer covering the surface thereof, and a method for detecting a biochemical substrate using the mesoporous platinum electrode. Using the present invention, glucose concentration can be selectively determined while excluding interference of interfering agents.

Abstract: The present invention relates to the microsphere whose surface is covered with hot spots and the method for identifying chemicals through Surface Enhanced Raman Scattering (SERS) using the same. The microsphere having hot spots, according to the present invention, includes a microsphere and metal networks as a shell which covers the surface of the microsphere, and nano-sized pores are distributed randomly on the surface or in the interstitial space of the metal networks. The microsphere having hot spots, according to the present invention, can be individually manipulated under a conventional optical microscope. SERS spectra of the monolayer of molecules on Pt or Au can be measured using single microsphere having hot spots mentioned as a sensitive probe. The microsphere having hot spots can be applied for decoding the microspheres with Raman tags flowing in a microfluidic system.

Abstract: The present invention provides a heat treatment method of an aluminum alloy panel, which can prevent surface curvature of molded aluminum alloy panel. For this purpose, the present heat treatment methods comprise: cold rolling an aluminum alloy panel at a reduction ratio of 45 to 50% at a final pass in a cold rolling process; first heat-treating the cold-rolled aluminum alloy panel at 450 to 510° C. for 3 hours; rapidly cooling the heat-treated aluminum alloy panel at a rate 60° C./sec or higher after the first heat treatment; and second heat-treating the rapidly cooled aluminum alloy panel at 200 to 220° C.

Abstract: The present invention relates to a microchip using polyelectrolyte salt bridge for cytometry, velocimetry, and cell sorting. The microchip comprises; a) an inlet for solution to be analyzed, b) a microchannel which provides a moving passage for solution to be analyzed, c) at least one outlet for solution to be analyzed which has passed through the moving passage, d) at least one electrode system comprising a first and a second salt bridges connected to the microchannel (the two salt bridges face each other), and a first and a second reservoirs connected to said each salt bridge (the reservoir comprises electrode and standard electrolyte solution). The microchip detects analytes in the solution to be analyzed (for example, a cell) by detecting change of impedance. In detail, anion in the standard electrolyte solution, which is comprised in the first reservoir, moves from the first salt bridge to the second salt bridge across the microchannel.

Abstract: The present invention discloses a high strength and high toughness aluminum alloy for a bumper beam and a method for manufacturing the same. The method includes: casting into a billet an aluminum alloy which comprises aluminum as a principal element, silicon (Si) of 0.1 wt. % or less, ferrum (Fe) of 0.2 wt. % or less, copper of 0.45 wt. % to 0.60 wt. %, manganese (Mn) of 0.1 wt. % to 0.20 wt. %, magnesium (Mg) of 1.3 wt. % to 1.5 wt. %, chromium (Cr) of 0.1 wt. % or less, zinc of 4.5 wt. % to 5.1 wt. %, titanium (Ti) of 0.04 wt. % or less, zirconium (Zr) of 0.08 wt. % to 0.12 wt. %, and inevitable impurities of 0.15 wt. % or less; extruding the billet into a predetermined form to form an extrusion; performing a solid-solutionization process to quench the extrusion; subjecting the extrusion to an artificial age-hardening which is performed at a temperature of about 120° C. for 24 hours; and subjecting the extrusion an over age-hardening which is performed at a temperature of about 170° C. to 185° C.

Abstract: A stair system including an upper tread having a substantially planar body portion, a stair nose portion located at one side of the planar body portion, and a dado located behind the stair nose portion, at least one lower tread, the lower tread having a substantially planar body portion, a stair nose portion located at one side of the planar body portion, a dado located behind the stair nose portion, and a groove located at a side opposite the stair nose portion, and at least two risers, each riser having a substantially planar body portion. In the stair system, one of the at least two risers is receivable between the dado of the upper tread and the groove of the lower tread and the other of the at least two risers is receivable in the dado of the lower tread. Methods for assembling a stair system are also provided.

Abstract: A stair system including an upper tread having a substantially planar body portion, a stair nose portion located at one side of the planar body portion, and a dado located behind the stair nose portion, at least one lower tread, the lower tread having a substantially planar body portion, a stair nose portion located at one side of the planar body portion, a dado located behind the stair nose portion, and a groove located at a side opposite the stair nose portion, and at least two risers, each riser having a substantially planar body portion. In the stair system, one of the at least two risers is receivable between the dado of the upper tread and the groove of the lower tread and the other of the at least two risers is receivable in the dado of the lower tread. Methods for assembling a stair system are also provided.