Patents by Inventor Dong-Fang Yu

Dong-Fang Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water soluble paclitaxel derivatives
    Publication number: 20030073615
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: May 17, 2002
    Publication date: April 17, 2003
    Applicant: Cell Therapeutics, Inc.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030073617
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: October 28, 2002
    Publication date: April 17, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Patent number: 6515017
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: February 4, 2003
    Assignee: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David Yang
  • Water soluble paclitaxel derivatives
    Patent number: 6441025
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: August 27, 2002
    Assignee: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • WATER SOLUBLE PACLITAXEL DERIVATIVES
    Publication number: 20010034363
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: March 30, 1998
    Publication date: October 25, 2001
    Inventors: CHUN LI, SIDNEY WALLACE, DONG-FANG YU, DAVID J. YANG
  • Water soluble paclitaxel prodrugs
    Patent number: 6262107
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: July 17, 2001
    Assignee: PG-TXL Company L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel prodrugs
    Patent number: 5977163
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: March 11, 1997
    Date of Patent: November 2, 1999
    Assignee: PG-TXL Company, L. P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang