Patents by Inventor Dong-Ho Woo
Dong-Ho Woo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230190862Abstract: The present invention relates to a composition for the prevention, amelioration, or treatment of urination-related disases, comprising cephalotocin. The cephalotocin according to the present invention modulates oxytocin receptors and vasopressin receptors, and has the effect of reducing urine volume by promoting water reabsorption in the kidneys. This means that cephalotocin has a significant antidiuretic effect, and thus, the cephalotocin of the present invention can be variously used in the field of prevention, amelioration, or treatment of urinary disorders or urination-related diseases.Type: ApplicationFiled: October 7, 2022Publication date: June 22, 2023Applicants: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, NATIONAL MARINE BIODIVERSITY INSTITUTE OF KOREAInventors: Seon Mi JO, Seung Hyun JUNG, Ki Hyun KIM, Dae Sung LEE, Dong Ho WOO, Ye Ji KIM, Chang hoon CHOI, Joung Wook SEO
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Patent number: 11273000Abstract: A stereotactic device for primate brains indicates a brain coordinate reference point of a primate using a simulator for indicating a brain coordinate reference point, thereby providing an initial setting to a zero point corresponding to the brain coordinate reference point. The brain coordinate reference point is conveniently and accurately indicated without relatively expensive equipment, such as a magnetic resonance imaging (MRI) scanner, to determine brain coordinates of the primate, so that a targeting procedure can be conducted on the brain.Type: GrantFiled: July 19, 2018Date of Patent: March 15, 2022Assignees: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Hyung Sun Kim, Su Cheol Han, Dong Ho Woo, Young Su Yang, Goo Hwa Kang, Hyung Ihl Kim, Ji Young Park, Dong Hak Byun
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Publication number: 20190175299Abstract: A stereotactic device for primate brains indicates a brain coordinate reference point of a primate using a simulator for indicating a brain coordinate reference point, thereby providing an initial setting to a zero point corresponding to the brain coordinate reference point. The brain coordinate reference point is conveniently and accurately indicated without relatively expensive equipment, such as a magnetic resonance imaging (MRI) scanner, to determine brain coordinates of the primate, so that a targeting procedure can be conducted on the brain.Type: ApplicationFiled: July 19, 2018Publication date: June 13, 2019Inventors: Hyung Sun KIM, Su Cheol HAN, Dong Ho WOO, Young Su YANG, Goo Hwa KANG, Hyung Ihl KIM, Ji Young PARK, Dong Hak BYUN
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Patent number: 9458120Abstract: The present invention relates to a novel phenoxypropanol derivative, represented by the structure of Chemical Formula I, and a racemate thereof, a pharmaceutically acceptable salt thereof, a solvate thereof and a hydrate thereof, wherein * represents an (R)-form or an (S)-form, X is selected from the group consisting of hydrogen, halogen and substituted or unsubstituted straight or branched alkyl having 1 to 4 carbon atoms, and n represents the number of X and an integer of 1 to 5, wherein at least a hydrogen is substituted with halogen in the substituted linear or branched alkyl having 1 to 4 carbon atoms. The derivative can be used for blocking T-type calcium channel and/or TREK channel, and for preventing and/or treating T-type calcium channel- and/or TREK channel-associated diseases.Type: GrantFiled: November 30, 2012Date of Patent: October 4, 2016Assignee: KORBA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Eun-Joo Roh, Kye-Jung Shin, Changjoon Justin Lee, Soo Jin Oh, Jung-Eun Park, Jeong Eun Yang, Eun Mi Hwang, Dong Ho Woo, Soon-Hyouk Lee, Dong-Gyu Kim, Hee-jung Chun, Wan-Keun Ji, Yun-Soo Na
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Publication number: 20150166496Abstract: The present invention relates to a novel phenoxypropanol derivative, use thereof for blocking T-type calcium channel and/or TREK channel, and use thereof for preventing and/or treating T-type calcium channel- and/or TREK channel-associated diseases.Type: ApplicationFiled: November 30, 2012Publication date: June 18, 2015Inventors: Eun-Joo Roh, Kye-Jung Shin, Changjoon Justin Lee, Soo Jin Oh, Jung-Eun Park, Jeong Eun Yang, Eun Mi Hwang, Dong Ho Woo, Soon-Hyouk Lee, Dong-Gyu Kim, Hee-jung Chun, Wan-Keun Ji, Yun-Soo Na
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Patent number: 8871463Abstract: The present invention investigate the two modes of glutamate release and the releasing rate of glutamate, and thus can provide a useful technique for neuron protection and acceleration of neurotransmission by controlling the glutamate release in astroctye. Thus, the present invention provides an inhibitor of the fast-mode release and/or the slow-mode release of astrocytic glutamate, a screening method of the inhibitor and a pharmaceutical composition or method of ameliorating, preventing and/or treating the disease associated with the over-release of glutamate via the Ca2+-activated anion channel, with the inhibition of fast-mode glutamate release.Type: GrantFiled: July 23, 2013Date of Patent: October 28, 2014Assignee: Korea Institute of Science and TechnologyInventors: Changjoon Justin Lee, Soo Jin Oh, Eun Mi Hwang, Dong Ho Woo
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Publication number: 20140093490Abstract: The present invention investigate the two modes of glutamate release and the releasing rate of glutamate, and thus can provide a useful technique for neuron protection and acceleration of neurotransmission by controlling the glutamate release in astroctye. Thus, the present invention provides an inhibitor of the fast-mode release and/or the slow-mode release of astrocytic glutamate, a screening method of the inhibitor and a pharmaceutical composition or method of ameliorating, preventing and/or treating the disease associated with the over-release of glutamate via the Ca2+-activated anion channel, with the inhibition of fast-mode glutamate release.Type: ApplicationFiled: July 23, 2013Publication date: April 3, 2014Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Changjoon Justin LEE, Soo Jin OH, Eun Mi HWANG, Dong Ho WOO
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Publication number: 20120232127Abstract: A novel use of anion channels, preferably Ca2+-activated anion channels (CAACs), in regulating release of neurotransmitters from neurons and/or astrocytes is provided. More specifically, CAAC activity regulators, agents for regulating neurotransmitter release comprising such CAAC activity regulators, and methods of screening agents for regulating neurotransmitter release using CAAC as a target.Type: ApplicationFiled: March 13, 2012Publication date: September 13, 2012Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Justin Changjoon LEE, Dong-Ho Woo, Hyung-Ju Park, Hye-Kyung Park
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Publication number: 20110201668Abstract: A novel use of anion channels, preferably Ca2+-activated anion channels (CAACs), in regulating release of neurotransmitters from neurons and/or astrocytes is provided. More specifically, CAAC activity regulators, agents for regulating neurotransmitter release comprising such CAAC activity regulators, and methods of screening agents for regulating neurotransmitter release using CAAC as a target.Type: ApplicationFiled: January 30, 2008Publication date: August 18, 2011Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Justin Changjoon Lee, Dong-Ho Woo, Hyung-Ju Park, Hye-Kyung Park
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Patent number: 7842471Abstract: The present invention relates to a novel use of a transfected cell as a biosensor, wherein the transfected cell expresses a receptor specific to a bio-signal transmitter, and a highly sensitive detector and a highly sensitive detecting method of a bio-signal transmitter using the biosensor. The bio-signal transmitter detecting technique according to the present invention has an advantage of being applied to a sniffer-patch method, and is capable of providing millisecond time resolution for detecting nanomolar levels of the bio-signal transmitter to be detected.Type: GrantFiled: January 30, 2008Date of Patent: November 30, 2010Assignee: Korea Institute of Science and TechnologyInventors: Changjoon Justin Lee, Dong-Ho Woo
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Publication number: 20080299109Abstract: The present invention relates to a novel communication mechanism between astrocytes and neurons at a synapse. More specifically, the present invention relates to a signaling mechanism between astrocytes and neurons, by activating astrocytic G-protein coupled receptors, thereby activating glutamate receptors on a membrane of neighboring postsynaptic neurons, resulting in increasing the level of intracellular Ca2+ and inducing a depolarization inward current to control neurotransmission in neurons.Type: ApplicationFiled: January 30, 2008Publication date: December 4, 2008Applicant: Korea Institute of Science and TechnologyInventors: Changjoon Justin LEE, Dong-Ho Woo, Stephen F. Traynelis
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Patent number: 6838099Abstract: The present invention relates to a high yield process for producing soluble dietary fiber from corn hull. More specifically, the present invention comprises removing starch and protein with enzymes from corn hull which is by-product of wet-milling process for production of corn starch, extracting the resultant with alkaline solution to form a alkaline extract, treating the alkaline extract with enzymes, and drying the enzyme-treated solution, to produce dietary fiber with low viscosity and containing hemicellulose as a major component at high yield.Type: GrantFiled: October 18, 2001Date of Patent: January 4, 2005Assignee: Samyang Genex CorporationInventors: Dong-Ho Woo, Jin-Keun Kim
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Publication number: 20030003216Abstract: The present invention relates to a high yield process for producing soluble dietary fiber from corn hull. More specifically, the present invention comprises removing starch and protein with enzymes from corn hull which is by-product of wet-milling process for production of corn starch, extracting the resultant with alkaline solution to form a alkaline extract, treating the alkaline extract with enzymes, and drying the enzyme-treated solution, to produce dietary fiber with low viscosity and containing hemicellulose as a major component at high yield.Type: ApplicationFiled: June 19, 2002Publication date: January 2, 2003Inventors: Dong-Ho Woo, Jin-Keun Kim