Abstract: Provided is a method for evaluating the efficacy of an anticancer drug using a mixture of peripheral blood mononuclear cells and cancer organoids; a method for screening the anticancer drug; a system for evaluating the efficacy of the anticancer drug; or a system for screening the anticancer drug. Specifically, the present invention relates to: a method for evaluating the efficacy of an anticancer drug using a mixture of cytotoxic T cells differentiated from PBMCs and cancer organoids; a method for screening the anticancer drug; a system for evaluating the efficacy of the anticancer drug; or a system for screening the anticancer drug. The method for evaluating the efficacy of an anticancer drug, the screening method, the efficacy evaluation system, or the screening system according to the present invention can very closely reproduce a tumor microenvironment, which is the form in which cancer cells exist in a living body.

Abstract: In a battery pack, a battery monitoring circuit is connected to a battery module including a plurality of battery cells to monitor the battery module. The detection sensor detects an electrolyte leaking in the battery module, and includes a first resistor and a second resistor connected in series between a power supply supplying a first voltage and a ground terminal, and a variable resistor connected to the first resistor in parallel and having a resistance that varies depending on the electrolyte leaking in the battery module. The detection sensor transfers, as a sensing voltage, a voltage at a contact between the first resistor and the second resistor to an input terminal of the battery monitoring circuit.

Abstract: The present invention relates to a genetic biocontainment technology to prevent theft or misuse of biological resources (e.g., nucleic acid molecule, plasmid or microbial strain containing the nucleic acid molecule, or sequence information associated with the nucleic acid molecule) using a quadruplet codon and decoding system thereof. In particular, the present invention relates to a system or a microbial strain comprising a nucleic acid molecule in which a triplet codon encoding a specific amino acid in a nucleic acid sequence has been replaced with a quadruplet codon, wherein genetic biocontainment occurs in an environment where tRNA for the quadruplet codon does not exist, and a method using the same. The present invention also relates to a biocontainment method to protect sequence information using a quadruplet codon.

Abstract: A processor of a battery apparatus detects voltages of a first terminal and a second terminal of a relay coil included in a relay before closing the relay to operate the heater, and diagnoses the heater based on a voltage which the voltage of the first terminal and the voltage of the second terminal correspond to among a high voltage and a low voltage for driving the relay, and a voltage for diagnosis.

Abstract: Provided are an optimal stimulation position combination determination method using a preset guide system, a server, and a computer program. The optimal stimulation position combination determination method using a preset guide system according to various embodiments of the present invention is executed by a computing device and includes: simulating electric stimulation for a brain of a subject by using a plurality of stimulation position according to a preset guide system; and determining an optimal stimulation position combination for applying the electric stimulation to the preset target point in the brain of the subject by using a simulation result of the electric stimulation.

Abstract: The embodiments disclosed herein are directed to an apparatus and method for managing creator campaigns. According to an aspect of the embodiments, there is provided an apparatus for managing creator campaigns, the apparatus including: memory; and a controller configured to provide a creator campaign and provide a reward to a supporter for a creator who has completed performing the creator campaign.

Abstract: A rear seat apparatus for a vehicle includes a back frame and a cushion frame. The back frame is not interlocked with the cushion frame and is individually rotated in the forward-and-rearward direction independently of the cushion frame. The cushion frame is not interlocked with the back frame and individually slides in the forward-and-rearward direction independently of the back frame. A front seating state and a rear seating state of a passenger are implemented through individual sliding movement of the cushion frame in the forward-and-rearward direction.

Abstract: The present invention relates to a method of providing diagnosis assistance information by analyzing a medical image, the method including obtaining an image of the brain, labeling a feature value representing a region of the brain, determining a reference boundary in the image of the brain, calculating a first disease index and a second disease index, and providing diagnosis assistance information on the basis of the first and second disease indexes.

Abstract: The present invention relates to a method of providing diagnosis assistance information by analyzing a medical image, the method including obtaining an image of the brain, labeling a feature value representing a region of the brain, determining a reference boundary in the image of the brain, calculating a first disease index and a second disease index, and providing diagnosis assistance information on the basis of the first and second disease indexes.

Abstract: The present invention relates to a method of providing diagnosis assistance information by analyzing a medical image, the method including obtaining an image of the brain, labeling a feature value representing a region of the brain, determining a reference boundary in the image of the brain, calculating a first disease index and a second disease index, and providing diagnosis assistance information on the basis of the first and second disease indexes.

Abstract: The present invention relates to a method of providing diagnosis assistance information by analyzing a medical image, the method including obtaining an image of the brain, labeling a feature value representing a region of the brain, determining a reference boundary in the image of the brain, calculating a first disease index and a second disease index, and providing diagnosis assistance information on the basis of the first and second disease indexes.

Abstract: A processor of a battery apparatus detects voltages of a first terminal and a second terminal of a relay coil included in a relay before closing the relay to operate the heater, and diagnoses the heater based on a voltage which the voltage of the first terminal and the voltage of the second terminal correspond to among a high voltage and a low voltage for driving the relay, and a voltage for diagnosis.

Abstract: The present invention relates to a method of providing diagnosis assistance information by analyzing a medical image, the method including obtaining an image of the brain, labeling a feature value representing a region of the brain, determining a reference boundary in the image of the brain, calculating a first disease index and a second disease index, and providing diagnosis assistance information on the basis of the first and second disease indexes.

Abstract: An all-solid-state battery manufacturing method. The method comprises the steps of: preparing an electrode assembly having a solid electrolyte layer between a positive electrode and a negative electrode; receiving the electrode assembly in a battery case; applying a first pressure to the battery case; and applying a second pressure and heat to the battery case.

Abstract: A method of analyzing a medical image includes acquiring a correction parameter computed based on a correlation between a first morphological value that is acquired from a first medical image acquired under a first scan condition and is related to a target element, and a second morphological value that is acquired from a second medical image acquired under a second scan condition and is related to the target element. A target medical image is acquired under the second scan condition. A target region related to the target element is acquired by segmenting the target medical image into regions corresponding to elements including the target element. A target morphological value related to the target element is based on voxel data corresponding to the target region. A corrected morphological value is based on the target morphological value and the correction parameter. A morphological index is outputted based on the corrected morphological value.

Abstract: A method of analyzing a medical image includes acquiring a correction parameter computed based on a correlation between a first morphological value that is acquired from a first medical image acquired under a first scan condition and is related to a target element, and a second morphological value that is acquired from a second medical image acquired under a second scan condition and is related to the target element. A target medical image is acquired under the second scan condition. A target region related to the target element is acquired by segmenting the target medical image into regions corresponding to elements including the target element. A target morphological value related to the target element is based on voxel data corresponding to the target region. A corrected morphological value is based on the target morphological value and the correction parameter. A morphological index is outputted based on the corrected morphological value.

Abstract: Disclosed are a novel Korean isolate of tomato yellow leaf curl virus (TYLCV) and infectious clones thereof, wherein: the use of an inventive recombinant vector comprising the nucleotide sequence of tomato yellow leaf curl virus (TYLCV) and Agrobacterium tumefaciens comprising the recombinant vector can effectively induce tomato yellow leaf curl virus infection in a crop even without an insect vector; an inventive infection system, compared with existing TYLCV Korean isolates, shows excellent infectivity in a plant, and thus can induce symptoms even in TYLCV-resistant varieties of tomatoes having existing widely used Ty-1 or Ty-2 resistant gene, so that the infectious system can be utilized as an artificial infection system in the future and can be applied in various studies in the future, such as a host plant range for tomato yellow leaf curl virus (TYLCV) and the correlation with the host plant.

Abstract: The present invention relates to a method for evaluating an efficacy of an anticancer drug or an anticancer drug candidate, comprising the step of treating a mixture of cancer organoids and immune cells with the anticancer drug or the anticancer drug candidate. In addition, it relates to the anticancer drug efficacy evaluation system or anticancer drug screening system comprising cancer organoids and immune cells. The mixture of cancer organoids and immune cells according to the present invention is mixed in a specific ratio, and accordingly can similarly reproduce a tumor microenvironment in which cancer cells exist in the body. Therefore, it can make it possible to accurately predict the efficacy of the drug when administered to a subject.

Abstract: A battery management system of a battery apparatus includes a circuit to which a voltage from a power supply is supplied and configured to be used to manage the battery pack. A processor of the battery management system controls the circuit, measure a voltage supplied from the power supply, and corrects the measured voltage based on a voltage drop occurred in the circuit.

Abstract: The present disclosure relates to a patch guide method, including at least: acquiring a matched model of a 3D scan model and a 3D brain MM model; capturing an image of the head of the object by using a depth camera; matching one location of the captured image and one location on the matched model; and determining a patch location on the head of the object, by using a 3D brain map. In the method, physical characteristics of areas included in the brain MRI image are acquired and used to generate the 3D brain map of the object. In the method, a target stimulus point, to which an electrical stimulus is to be applied in a brain of the object, is acquired and used in a simulation of a delivery process of the electrical stimulus to the target stimulus point from candidate stimulus positions, to determine the patch location.