Patents by Inventor Dong Jin Hong

Dong Jin Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12344618
    Abstract: A novel heterotricyclic compounds of Formula 1 or pharmaceutically acceptable salts thereof, and uses thereof are disclosed. The novel heterotricyclic compounds exhibit an inhibitory activity against EZH1 (enhancer of zeste homolog 1) and/or EZH2 (enhancer of zeste homolog 2) activity. Pharmaceutical compositions containing these compounds as active ingredient is also disclosed. The heterotricyclic compound, pharmaceutically acceptable salts thereof, or compositions containing the compound or salt are useful in treating tumor or cancer in a subject.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: July 1, 2025
    Assignee: HANMI PHARMACEUTICAL CO., LTD.
    Inventors: Dong Jin Hong, Seung Hyun Jung, Chang Hee Park, Seo Hee Kim, Ji Young Hwang, Young Gil Ahn
  • Patent number: 11535629
    Abstract: Disclosed are novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts thereof, optical isomers, hydrates, and solvates thereof as well as uses thereof. More specifically, the novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts, optical isomers, hydrates, solvates show inhibition activity of EZH1 (Enhancer of zeste homolog 1) and/or EZH2 (Enhancer of zeste homolog 2) activity. Pharmaceutical compositions containing the compound is also disclosed.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: December 27, 2022
    Assignee: HANMI PHARMACEUTICAL CO., LTD.
    Inventors: Seung Hyun Jung, Dong Jin Hong, Ji Young Hwang, Seo Hee Kim, So Min Park, Shin Mee Mah, Young Gil Ahn
  • Publication number: 20220275000
    Abstract: Disclosed are novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts thereof, optical isomers, hydrates, and solvates thereof as well as uses thereof. More specifically, the novel dioxoisoquinolinone derivative compounds, pharmaceutically acceptable salts, optical isomers, hydrates, solvates show inhibition activity of EZH1 (Enhancer of zeste homolog 1) and/or EZH2 (Enhancer of zeste homolog 2) activity. Pharmaceutical compositions containing the compound is also disclosed.
    Type: Application
    Filed: May 20, 2021
    Publication date: September 1, 2022
    Applicant: HANMI PHARMACEUTICAL CO., LTD.
    Inventors: Seung Hyun JUNG, Dong Jin HONG, Ji Young HWANG, Seo Hee KIM, So Min PARK, Shin Mee MAH, Young Gil AHN
  • Publication number: 20220135582
    Abstract: A novel heterotricyclic compounds of Formula 1 or pharmaceutically acceptable salts thereof, and uses thereof are disclosed. The novel heterotricyclic compounds exhibit an inhibitory activity against EZH1 (enhancer of zeste homolog 1) and/or EZH2 (enhancer of zeste homolog 2) activity. Pharmaceutical compositions containing these compounds as active ingredient is also disclosed. The heterotricyclic compound, pharmaceutically acceptable salts thereof, or compositions containing the compound or salt are useful in treating tumor or cancer in a subject.
    Type: Application
    Filed: February 19, 2020
    Publication date: May 5, 2022
    Applicant: HANMI PHARMACEUTICAL CO., LTD.
    Inventors: Dong Jin HONG, Seung Hyun JUNG, Chang Hee PARK, Seo Hee KIM, Ji Young HWANG, Young Gil AHN
  • Patent number: 8637700
    Abstract: The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: January 28, 2014
    Assignee: Hanmi Science Co., Ltd
    Inventors: Sang Min Yun, Dong Jin Hong, Weon Ki Yang, Jae Ho Yoo, Ji Sook Kim, Moon Sub Lee, Han Kyong Kim, Eun Jung Lim, Young Ho Moon, Young-Kil Chang, Gwan Sun Lee
  • Patent number: 8242288
    Abstract: Provided is a method of preparing a (6R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydropyran-2-one, and a (5R)-2-hexyl-5-hydroxy-3-iminohexadecanoate derivative used in said method as an intermediate.
    Type: Grant
    Filed: October 29, 2008
    Date of Patent: August 14, 2012
    Assignee: Hanmi Holdings Co., Ltd.
    Inventors: Sang Min Yun, Young Ho Moon, Young-Kil Chang, Dong Jin Hong, Ji-Yeon Chang, Moon Sub Lee, Jaeho Yoo, Ji Sook Kim, Cheol Kyung Kim
  • Publication number: 20110178330
    Abstract: The present invention relates to a high-yield method for preparing highly pure (3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyl-2-oxetanone using a metal salt of (2S,3S,5R)-2-hexyl-3,5-dihydroxyhexadecanoic acid as an intermediate.
    Type: Application
    Filed: October 30, 2009
    Publication date: July 21, 2011
    Applicant: HANMI HOLDINGS CO., LTD.
    Inventors: Sang Min Yun, Dong Jin Hong, Weon Ki Yang, Jae Ho Yoo, Ji Sook Kim, Moon Sub Lee, Han Kyong Kim, Eun Jung Lim, Young Ho Moon, Young-Kil Chang, Gwan Sun Lee
  • Publication number: 20100274029
    Abstract: Provided is a method of preparing a (6R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydropyran-2-one, and a (5R)-2-hexyl-5-hydroxy-3-iminohexadecanoate derivative used in said method as an intermediate.
    Type: Application
    Filed: October 29, 2008
    Publication date: October 28, 2010
    Applicant: HANMI PHARM. CO., LTD.
    Inventors: Sang Min Yun, Young Ho Moon, Young-Kil Chang, Dong Jin Hong, Ji-Yeon Chang, Moon Sub Lee, Jaeho Yoo, Ji Sook Kim, Cheol Kyung Kim
  • Patent number: D408229
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: April 20, 1999
    Assignee: S. Michael Nostrant & Associates, Inc.
    Inventor: Dong Jin Hong