Patents by Inventor Dong Jo Chang

Dong Jo Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT
    Publication number: 20150183797
    Abstract: The present invention relates to a compound inhibiting Hsp90 and a pharmaceutical composition comprising the same as an active ingredient. The compounds represented by formula 1 and formula 2 of the present invention suppress the expression of Hsp90 so that they can inhibit the accumulation of HIF-1?, the Hsp90 client protein, and also efficiently inhibit the activation of VEGF. In addition, these compounds display low cytotoxicity, so that they can be effectively used as an active ingredient of an anti-cancer agent, a diabetic retinopathy treating agent, and an anti-arthritic agent.
    Type: Application
    Filed: January 2, 2015
    Publication date: July 2, 2015
    Applicant: SNU R&DB FOUNDATION
    Inventors: Young-Ger SUH, Dong-Jo CHANG, Hongchan AN, Kyu-Won KIM, Young-Myeong KIM, Ho-Young LEE
  • Tricyclic derivatives and their use
    Patent number: 7622612
    Abstract: The present invention relates to tricyclic colchicine derivatives represented by the formulas (I) or (II), pharmaceutically acceptable salts thereof, and a method for providing an immuno-suppressive or immuno-modulating effect, an anti-proliferative effect, an anti-inflammatory effect or a method for treating cancer comprising administering to a patient an effective amount of one or more colchicine derivatives:
    Type: Grant
    Filed: July 10, 2006
    Date of Patent: November 24, 2009
    Assignees: Chemtech Research Incorporation, KT & G Corporation
    Inventors: Dong Jo Chang, Eun Young Yoon, Gun Bong Lee, Soon Ok Kim, Wan Joo Kim
  • Novel tricyclic derivatives and their use
    Publication number: 20070021427
    Abstract: The present invention relates to tricyclic colchicine derivatives represented by the formulas (I) or (II), pharmaceutically acceptable salts thereof, and a method for providing an immuno-suppressive or immuno-modulating effect, an anti-proliferative effect, an anti-inflammatory effect or a method for treating cancer comprising administering to a patient an effective amount of one or more colchicine derivatives:
    Type: Application
    Filed: July 10, 2006
    Publication date: January 25, 2007
    Applicants: CHEMTECH RESEARCH INCORPORATION, KT&G Corporation
    Inventors: Dong Jo Chang, Eun Yoon, Gun Lee, Soon Kim, Wan Kim