Abstract: The present invention relates to a pharmaceutical composition of the compound of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, as well as a pharmaceutical formulation thereof. The present invention also relates to a process for preparing the pharmaceutical composition and the pharmaceutical formulation, and use of the same in the manufacture of a medicament for treating a PDE3/4-mediated disease.

Abstract: An equalizing circuit has a first current summer and a first sampler. The first current summer may be configured to sum currents representative of a data signal and a first plurality of feedback signals when enabled by a first control signal. The first current summer may be enabled when the first control signal is in a first signaling state and disabled when the control signal is in a first signaling state. The first sampler may be configured to sample an output of the first current summer in accordance with timing provided by a first sampling clock signal. The first control signal may be in the first signaling state for a duration that is longer than a unit interval that defines the interval in which a bit of data is encoded in the data signal.

Abstract: Disclosed is an electrolyte composition comprising a lithium salt, an imidazolium ionic liquid, and an organic solvent with a high boiling point. In one embodiment, the high boiling point is 100° C. or above. The electrolyte and an electrochemical device comprising the same exhibit an improved thermal stability and safety.

Abstract: Disclosed is an electrolyte comprising a cyclic quaternary ammonium ionic liquid, a lithium salt, and an organic solvent with a high boiling point. In one embodiment, the organic solvent has a boiling point of at least 100° C. In one embodiment, the cyclic quaternary ammonium ionic liquid and the lithium salt share the same anion. An electrochemical device comprising the same and preparation method therefor are also disclosed.

Abstract: A pharmaceutical composition comprising a Dipeptidyl Peptidase 1 (DPP1) small molecule inhibitor, Compound A, and a preparation method thereof, and a use of the pharmaceutical composition in the treatment of diseases or conditions associated with fibrotic bronchiectasis.

Abstract: An equalizing circuit has a first current summer and a first sampler. The first current summer may be configured to sum currents representative of a data signal and a first plurality of feedback signals when enabled by a first control signal. The first current summer may be enabled when the first control signal is in a first signaling state and disabled when the control signal is in a first signaling state. The first sampler may be configured to sample an output of the first current summer in accordance with timing provided by a first sampling clock signal. The first control signal may be in the first signaling state for a duration that is longer than a unit interval that defines the interval in which a bit of data is encoded in the data signal.

Abstract: Provided herein are methods of preparing electrodes. The method comprises: combining an electroactive material, an electron conductive material, an electrolyte, and a polymeric binder, to form an active mixture; and shaping the active mixture to form an electrode. In some embodiments, the electrolyte comprises a salt and a nonaqueous solvent of the salt. In some embodiments, the solvent of the salt does not dissolve the polymeric binder. In some embodiments, the method does not include a drying step to remove the solvent and the nonaqueous solvent remains in the active mixture and the electrode. In some embodiments, the electrode as prepared has an areal capacity of at least 2 mAh/cm2 and a thickness of at least 30 ?m.

Abstract: Aspects of a charge pump with reduced leakage current are disclosed. An apparatus includes a main branch having two parallel lines of switches and a main branch output, a side branch coupled to the main branch having two parallel lines of switches and a side branch output and a charge pump output at which the main branch output and the side branch output are coupled together.

Abstract: Aspects of a charge pump with reduced leakage current are disclosed. An apparatus includes a main branch having two parallel lines of switches and a main branch output, a side branch coupled to the main branch having two parallel lines of switches and a side branch output and a charge pump output at which the main branch output and the side branch output are coupled together.

Abstract: Disclosed is an electrochemical cell having a polymer solid electrolyte comprising a polymer localized on surface of an electrode. In one aspect, the localized polymer physically decreases or prevents exposure of freshly cracked electrode to a flammable solvent under extreme conditions, thus leading to an improved safety profile of the cell. In one aspect, the disclosure provides a polymer solid electrolyte comprising a polymer localized on surface of an electrode. Methods for preparing the same are also disclosed.

Abstract: An aerial guided pillar track vehicle travel system, including a pillar track electric vehicle and an aerial guided power supply system; wherein the pillar track electric vehicle comprises a coupling seat, a guiding pillar, a pillar track adaptive navigation system, elastic accessories, a first guiding strip and a second guiding strip, a rotating rod, a transmission component, a steering and transmission device of the pillar track electric vehicle, and a power assisting device. It solves the problem of driver driving and electronic guidance of autonomous vehicle in life, which can not avoid the safety risk of driving guidance caused by delayed response, and solves the carbon neutrality problem of public transportation; Suitable for automatic driving and manual assisted driving inside the air guided pillar track; Belonging to a new type of pillar track electric vehicle rail transit, energy-saving and environmental protection system.

Abstract: The present invention generally relates to electrolytes for use in various electrochemical devices. In some cases, the electrolytes are relatively safe to use; for example, the electrolytes may be resistant to overheating, catching on fire, burning, exploding, etc. In some embodiments, such electrolytes may be useful for certain types of high-voltage cathode materials. In some cases, the electrolytes may include ion dissociation compounds that can dissociate tight ion pairs. Non-limiting examples of ion dissociation compounds include trialkyl phosphates, sulfones, or the like. Other aspects of the invention are generally directed to devices including such electrolytes, methods of making or using such electrolytes, kits including such electrolytes, or the like.

Abstract: The present invention generally relates to electrolytes for use in various electrochemical devices. In some cases, the electrolytes are relatively safe to use; for example, the electrolytes may be resistant to overheating, catching on fire, burning, exploding, etc. In some embodiments, such electrolytes may be useful for certain types of high-voltage cathode materials. In some cases, the electrolytes may include ion dissociation compounds that can dissociate tight ion pairs. Non-limiting examples of ion dissociation compounds include trialkyl phosphates, sulfones, or the like. Other aspects of the invention are generally directed to devices including such electrolytes, methods of making or using such electrolytes, kits including such electrolytes, or the like.

Abstract: Provided herein are electrolyte compositions suitable for electrochemical devices such as batteries, capacitors, sensors, condensers, electrochromic elements, photoelectric conversion elements, and the like.

Abstract: Disclosed is an electrolyte composition comprising an electrolyte salt, a monomer and an initiator that does not include any groups leading to gas formation during polymerization of the monomer. Also disclosed is an electrolyte composition comprising an electrolyte salt, a monomer and an initiator, wherein the electrolyte composition has a long shelf life. In one embodiment, the electrolyte composition has a viscosity of less than 1000 cP after it is stored 25° C. for 14 days. The disclosure further provides a polymer electrolyte synthesized from the electrolyte composition. In one embodiment, the polymer electrolyte is substantially free of visible bubbles. An electrochemical device comprising the same and preparation method therefor are also disclosed.

Abstract: Disclosed are various polymer solid electrolyte materials suitable for various electrochemical devices and methods for making or using the same. The polymer solid electrolyte comprises a crosslinked polymer from a polymer. Certain embodiments are generally directed to solid electrolytes having relatively high ionic conductivity and/or other mechanical or electrical properties, e.g., tensile strength or decomposition potential. Certain aspects include a polymer, a plasticizer, and an electrolyte salt. In some cases, the polymer for synthesizing the crosslinked polymer may exhibit certain structures such as: where R1 can be one of the following groups: where n is an integer between 1 and 10000, m is an integer between 1 and 5000, and R2 to R6 are each independently selected from the group consisting of hydrogen, methyl, ethyl, phenyl, benzyl, acryl, epoxy ethyl, isocyanate, cyclic carbonate, lactone, lactam, and vinyl; and * indicates a point of attachment.

Abstract: A polymer electrolyte includes an additive and a crosslinked polymer with a heterogeneous polymer network synthesized from one or more crosslinkers, wherein at least one crosslinker has three or more polymerizable terminals. In another embodiment, the crosslinked polymer has a polymer network with topological defects. In some embodiments, the additive comprises element F and at least one of elements B and P. In some embodiments, the additive comprises F—B, F—P, F—P—O, F—P=O, or any combinations thereof. In one embodiment, the crosslinked polymer is not over-crosslinked. An electrochemical device with the crosslinked polymer as electrolyte exhibits an improved electrochemical and safety performance.

Abstract: A clock recovery circuit includes a frequency tracking loop including a first charge pump, and a phase tracking loop including a second charge pump. A voltage-controlled oscillator responds to the frequency tracking loop in a first operating mode and to the phase tracking loop in a second operating mode. A lock detector outputs an activation signal that indicates whether the clock recovery circuit has acquired frequency lock. A loop filter coupled to an input of the voltage-controlled oscillator includes a switchable resistor and a programmable delay element responsive to the activation signal. The first charge pump is disabled when the activation signal indicates frequency lock has been acquired, and disabled when the activation signal indicates frequency lock has not been acquired. The switchable resistor is bypassed when an output of the programmable delay element is in the first signaling state.

Abstract: A clock recovery circuit includes a frequency tracking loop including a first charge pump, and a phase tracking loop including a second charge pump. A voltage-controlled oscillator responds to the frequency tracking loop in a first operating mode and to the phase tracking loop in a second operating mode. A lock detector outputs an activation signal that indicates whether the clock recovery circuit has acquired frequency lock. A loop filter coupled to an input of the voltage-controlled oscillator includes a switchable resistor and a programmable delay element responsive to the activation signal. The first charge pump is disabled when the activation signal indicates frequency lock has been acquired, and disabled when the activation signal indicates frequency lock has not been acquired. The switchable resistor is bypassed when an output of the programmable delay element is in the first signaling state.

Abstract: The present invention generally relates to electrolytes for use in various electrochemical devices. In some cases, the electrolytes are relatively safe to use; for example, the electrolytes may be resistant to overheating, catching on fire, burning, exploding, etc. In some embodiments, such electrolytes may be useful for certain types of high-voltage cathode materials. In some cases, the electrolytes may include ion dissociation compounds that can dissociate tight ion pairs. Non-limiting examples of ion dissociation compounds include trialkyl phosphates, sulfones, or the like. Other aspects of the invention are generally directed to devices including such electrolytes, methods of making or using such electrolytes, kits including such electrolytes, or the like.