Patents by Inventor Dong-Ryun Oh

Dong-Ryun Oh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manufacturing method of solid dispersion containing itraconazole
    Patent number: 9492446
    Abstract: The present invention relates to a method for preparing an itraconazole-containing solid dispersion. The itraconazole-containing solid dispersion according to the preparing method of the present invention has both improved solubility and rapid dissolution rate so that it has an excellent bioavailability. The itraconazole-containing solid dispersion of the present invention is also independent of pH variation of human stomach so that it can minimize the absorption variation of intra- and inter-individuals. In addition, the itraconazole-containing solid dispersion according to the preparing method of the present invention is stable for a long time. The present invention also provides an economical and environment-friendly method for manufacturing an itraconazole-containing composition because the method adds a lactic acid in a solution comprising itraconazole to decrease the amount of an organic solvent needed to dissolve itraconazole.
    Type: Grant
    Filed: June 24, 2005
    Date of Patent: November 15, 2016
    Assignees: CTC BIO, Inc.
    Inventors: Hong-Ryeol Jeon, Se-Geun Yu, Bong-Sang Lee, Se-Heum Oh, Jeong-Seo Park, Dong-Ryun Oh, Do-Woo Kwon
  • Manufacturing method of solid dispersion containing itraconazole
    Publication number: 20090298847
    Abstract: The present invention relates to a method for preparing an itraconazole-containing solid dispersion. The itraconazole-containing solid dispersion according to the preparing method of the present invention has both improved solubility and rapid dissolution rate so that it has an excellent bioavailability. The itraconazole-containing solid dispersion of the present invention is also independent of pH variation of human stomach so that it can minimize the absorption variation of intra- and inter-individuals. In addition, the itraconazole-containing solid dispersion according to the preparing method of the present invention is stable for a long time. The present invention also provides an economical and environment-friendly method for manufacturing an itraconazole-containing composition because the method adds a lactic acid in a solution comprising itraconazole to decrease the amount of an organic solvent needed to dissolve itraconazole.
    Type: Application
    Filed: June 24, 2005
    Publication date: December 3, 2009
    Applicant: CTC BIO, INC.
    Inventors: Hong-Ryeol Jeon, Se-Geun Yu, Bong-Sang Lee, Se-Heum Oh, Jeong-Seo Park, Dong-Ryun Oh, Do-Woo Kwon
  • Pharmaceutical Composition Containing Sibutramine Free Base and Manufacturing Method Thereof
    Publication number: 20080194695
    Abstract: The present invention relates to a composition comprising sibutramine free base. The present invention provides a solid dispersion wherein sibutramine free base, acid and hydrophilic polymer are uniformly dispersed and a manufacturing method thereof. The composition of the present invention has improved dissolution rate compared to conventional compositions containing sibutramine free base or sibutramine hydrochloride, and is also stable during storage and can be easily mass-produced.
    Type: Application
    Filed: April 18, 2006
    Publication date: August 14, 2008
    Inventors: Hong-Ryeol Jeon, Do-Woo Kwon, Bong-Sang Lee, Se-Heum Oh, Dong-Ryun Oh, Jeong-Seo Park, Se-Geun Yu