Abstract: Provided is a multi-protein degradation agent having an imide skeleton, which can degrade multiple proteins comprising c-Myc, GSPT1, CK1? and IKZF (1/2/3) proteins, and therefore can be used for treating diseases or disorders related thereto, such as cancer.

Abstract: The present application relates to rubber accelerators, and specifically disclosed are a bimetallic synergistic rubber accelerator, a preparation method thereof, and a rubber product. The preparation method of the accelerator includes the following steps: Step S1, preparing a pre-precursor powder by a sol-gel method; Step S2, performing microwave synthesis; the Step S1 specifically includes the following steps: Step S11: dissolving a cobalt salt and a manganese salt in water, adding polyethylene glycol and then stirring evenly, and adjusting the pH to 7.5-8 with an alkali solution to obtain an initial reaction solution; Step S12: reacting the initial reaction solution at 50-70° C., then drying to obtain a xerogel, and then pulverizing and screening to obtain the pre-precursor powder. The accelerator of the present application can be used to prepare rubber products. The accelerator has the advantages of shortening the vulcanization time and improving the overall performance of the rubber products.

Abstract: A method and device for on-chip bus arbitration are disclosed. The method includes: dividing devices into a first level, a second level and a third level from high to low; and in each arbitration period, calculating remaining processing time of each real-time transaction, and upgrading a device making a request required to be processed immediately to the first level in the current arbitration period; monitoring bandwidth usage amount of devices of the first level and the second level respectively, and downgrading a device whose bandwidth usage amount exceeds a preset bandwidth threshold value to the third level in the current arbitration period; and in devices making requests for a bus use right, if a device of the highest level is the device of the first level, authorizing the device of the first level; and if it is not the device of the first level, authorizing a device making continuous requests.

Abstract: A client instant information service system and method is disclosed. The invention is a utility that can be operated with different OSs. The client/user only needs to execute one signal action to complete a given operation through the UOI (User Operating Interface) provided by the invention. The invention can also perform content updating, downloading, and browsing by instantly informing the client/user of any change on the server to achieve the purpose of real-time information/data transmission. The disclosed method includes the steps of: calling the interface generation module to generate user interfaces by the procedure control unit, calling the operation response module based on input messages of the client/user, calling the real-time data module to perform procedures and receiving an EXIT request from the client/user.