Patents by Inventor Dong Woo Ko

Dong Woo Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12378526
    Abstract: The invention relates to: a composition for culturing natural killer cells, comprising, as an active ingredient, a fusion protein comprising an IL-2 protein and a CD80 protein; and a method for preparing natural killer cells by using same. Particularly, a composition for culturing natural killer cells, comprising, as an active ingredient, a fusion protein comprising IL-2 or a variant thereof and CD80 or a fragment thereof, of the present invention; promotes the proliferation of natural killer cells, induces the expression of CD16 and NKp46, and increases the expression and secretion of granzyme B and perforin, thereby being effectively usable in the preparation of natural killer cells having an excellent anticancer immune function.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: August 5, 2025
    Assignee: GI CELL, INC.
    Inventors: Myoung Ho Jang, Chun-Pyo Hong, Dong Woo Ko, June Sub Lee
  • Publication number: 20220372442
    Abstract: The invention relates to: a composition for culturing natural killer cells, comprising, as an active ingredient, a fusion protein comprising an IL-2 protein and a CD80 protein; and a method for preparing natural killer cells by using same. Particularly, a composition for culturing natural killer cells, comprising, as an active ingredient, a fusion protein comprising IL-2 or a variant thereof and CD80 or a fragment thereof, of the present invention; promotes the proliferation of natural killer cells, induces the expression of CD16 and NKp46, and increases the expression and secretion of granzyme B and perforin, thereby being effectively usable in the preparation of natural killer cells having an excellent anticancer immune function.
    Type: Application
    Filed: May 17, 2022
    Publication date: November 24, 2022
    Inventors: Myoung Ho JANG, Chun-Pyo Hong, Dong Woo Ko, June Sub Lee