Abstract: A DNA movable type storage system and method based on movable type printing including: (1) construct a physical DNA movable type library of data payloads and a physical DNA movable type library of indexes based on “DNA movable type codebook”, which consist of a variety of DNA oligonucleotides corresponding to all “DNA payload movable type elements” and “DNA index movable type elements” in the two libraries, respectively; (2) transcode from the storage binary data into corresponding “DNA movable type units”, each of which contains corresponding DNA payload movable type elements and related DNA index movable type elements; (3) link the abovementioned DNA payload and index movable type elements to form a physical “DNA movable type unit”, and put all generated DNA movable type units together for DNA storage, which cover all data information of the target file.