Abstract: The present invention relates to compounds of Formula (I) as defined herein as well as conjugates comprising said compounds and pharmaceutical compositions comprising said compounds or conjugates. Also encompassed are methods for selectively detecting oligomeric proteins or peptides associated with a conformational disorder in a sample, and methods for diagnosing or treating a conformational disorder associated with protein or peptide oligomers in a subject.

Abstract: The present disclosure discloses a method and a device for loading a webpage. The method for loading a webpage includes: sending a webpage request message to a server; receiving an initial webpage of the webpage returned from the server, the initial webpage including an agent; sending a WebSocket connection request message to the server through the agent, to establish a WebSocket connection with the server; sending a page component request message of the webpage to the server based on the WebSocket connection, to load page component of the webpage; receiving the page components of the webpage returned from the server based on the WebSocket connection; and creating the page components at corresponding positions in the initial webpage.