Patents by Inventor Donghai Xiong

Donghai Xiong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene Expression Signature for Predicting Immunotherapy Response and Methods of Use
    Publication number: 20230304099
    Abstract: The present invention provides novel gene signature associated with immune checkpoint inhibitor (ICT) named ImmuneCells.Sig which is predicative of ICT outcomes of melanoma patients which is significantly more accurate than all previously reported ICT response signatures. The ImmuneCells.Sig can be used as an accurate predictor of ICT response and may be used to determine if a patient will be susceptible and respond to ICT treatment.
    Type: Application
    Filed: August 9, 2021
    Publication date: September 28, 2023
    Inventors: Donghai Xiong, Ming You, Yian Wang
  • GENE EXPRESSION SIGNATURE OF HYPERPROGRESSIVE DISEASE (HPD) IN PATIENTS AFTER ANTI-PD-1 IMMUNOTHERAPY
    Publication number: 20210110886
    Abstract: A method of determining a patient's HPD status comprising the steps of a) examining a patient tumor sample for the expression level of HPD-diagnostic biomarkers, and b) determining whether the signature of the biomarkers is similar to that of a HPD positive signature is disclosed.
    Type: Application
    Filed: October 14, 2020
    Publication date: April 15, 2021
    Inventors: Donghai Xiong, Ming You