Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: Text messages with alphanumeric addresses are delivered to mobiles and external short message entities (ESMEs) which do not support alphanumeric addressing, providing meaningful fallback handling. Additionally, the invention enables delivery of SMPP messages from ESME or SMPP networks which can only originate numeric addresses, yet provide for mapping to alphanumeric addresses for delivery to the mobile. A two-way mapping is provided between alphanumeric addresses and SMS short-codes to enable delivery of text messages with alphanumeric addressing in networks which contain mobiles and/or ESME's that lack support of alphanumeric addressing. An ESME can send a text message using an alphanumeric origination address, without knowing which handsets support the capability, and which do not, or whether handsets are on CDMA, or GSM, or UMTS, or long term evolution (LTE) networks, or can continue to send using a numeric origination address.

Abstract: Text messages with alphanumeric addresses are delivered to mobiles and external short message entities (ESMEs) which do not support alphanumeric addressing, providing meaningful fallback handling. Additionally, the invention enables delivery of SMPP messages from ESME or SMPP networks which can only originate numeric addresses, yet provide for mapping to alphanumeric addresses for delivery to the mobile. A two-way mapping is provided between alphanumeric addresses and SMS short-codes to enable delivery of text messages with alphanumeric addressing in networks which contain mobiles and/or ESME's that lack support of alphanumeric addressing. An ESME can send a text message using an alphanumeric origination address, without knowing which handsets support the capability, and which do not, or whether handsets are on CDMA, or GSM, or UMTS, or networks, or can continue to send using a numeric origination address. The SMSC provides conversions to alphanumeric addresses on behalf of the ESME and the mobile.

Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: This invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein R1, R2, R4. Ar and Het are as defined herein. The invention also relates to methods of using the compound of formula (I) to treat a diseases and disorders that are mediated or sustained through the activity of CCR10.

Abstract: Derivatives of 6,7-dihydro-5H-imidazo[1,2-?]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

Abstract: A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account.

Abstract: Text messages with alphanumeric addresses are delivered to mobiles and external short message entities (ESMEs) which do not support alphanumeric addressing, providing meaningful fallback handling. Additionally, the invention enables delivery of SMPP messages from ESME or SMPP networks which can only originate numeric addresses, yet provide for mapping to alphanumeric addresses for delivery to the mobile. A two-way mapping is provided between alphanumeric addresses and SMS short-codes to enable delivery of text messages with alphanumeric addressing in networks which contain mobiles and/or ESME's that lack support of alphanumeric addressing. An ESME can send a text message using an alphanumeric origination address, without knowing which handsets support the capability, and which do not, or whether handsets are on CDMA, or GSM, or UMTS, or networks, or can continue to send using a numeric origination address. The SMSC provides conversions to alphanumeric addresses on behalf of the ESME and the mobile.

Abstract: This invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein R1, R2, R4. Ar and Het are as defined herein. The invention also relates to methods of using the compound of formula (I) to treat a diseases and disorders that are mediated or sustained through the activity of CCR10.

Abstract: Derivatives of 6,7-dihydro-5H-imidazo[1,2-?]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

Abstract: The application relates to compounds of formula Ia and analogues thereof wherein R1 to R13 and X are as defined herein. The invention also relates to the use of the compounds of formula Ia as inhibitors of Mitogen-Activated Protein Kinase-Activated Protein kinase-2 (MAPKAP-k2), and also to a method for preventing or treating a disease or disorder that can be treated or prevented by modulating the activity of MAPKAP-K2 in a subject and to pharmaceutical compositions and kits that include these MAPKAP-K2 inhibitors.

Abstract: Disclosed are compounds of formula (I) Where Ar1, X, Y, Q, W, R3, R4, R5, R6 and Ry are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

Abstract: Disclosed are novel compounds of formula (I): wherein Ar1, X, Y, P, Q and Het are defined herein, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are pharmaceutical compositions comprising these compounds, processes for preparing these compounds and novel intermediate compounds useful in these processes.

Abstract: Disclosed are novel compounds of formula (I): 1

Abstract: Disclosed are novel compounds of formula (I): wherein Ar1, X, Y, P, Q and Het are defined herein, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are pharmaceutical compositions comprising these compounds, processes for preparing these compounds and novel intermediate compounds useful in these processes.