Patents by Inventor Donghua Zhu

Donghua Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240075026
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Application
    Filed: February 8, 2023
    Publication date: March 7, 2024
    Applicant: AbbVie Inc.
    Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
  • Publication number: 20240000749
    Abstract: The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient; and one of or a combination of methacrylic acid copolymer, or a cellulose derivative wherein the active pharmaceutical ingredient is a dengue viral replication inhibitor. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of prevention and/or treatment and/or inhibition of viral replication are also described.
    Type: Application
    Filed: November 3, 2021
    Publication date: January 4, 2024
    Inventors: Donghua Zhu, Kristof Leonard Kimpe, Sune Klint Andersen, Matthieu Jean M. Ravelingien, Ivan Henri M. Somers
  • Publication number: 20230310413
    Abstract: Described herein are pharmaceutical formulations comprising a MALT1 inhibitor and a mixture comprising fatty acid and polyethylene glycol monoesters and diesters, and optionally, fatty acid and glycerol monoesters, diesters and triesters. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.
    Type: Application
    Filed: August 20, 2021
    Publication date: October 5, 2023
    Inventors: Sanket Manoj SHAH, Donghua ZHU, René HOLM, Kristof Leonard KIMPE
  • Publication number: 20230301924
    Abstract: The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient, glyceryl palmitostearate, and D-?-tocopherol polyethylene glycol succinate (TPGS). Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.
    Type: Application
    Filed: November 3, 2021
    Publication date: September 28, 2023
    Inventors: Donghua Zhu, Kristof Leonard Kimpe, Kim Alda Verwaest
  • Publication number: 20220405517
    Abstract: A system and method for recognizing traffic signs during autonomous driving comprises a camera module obtaining a first recognition, a sensor obtains behavior information of the host vehicle and of nearby vehicles and a connected training module generates parameters for traffic sign recognition according to information as to the behavior of the host vehicle and the nearby vehicles. A recurrent neural network module is connected with the training module and the camera module, and outputs a second traffic sign recognition according to the parameters and the first recognition. Training parameters of the second recognition comprise the traffic sign recognition parameters and the first recognition, the accuracy of the training result being improved by combining other sensors to perform traffic sign recognition training.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 22, 2022
    Inventors: Xiaosheng SHI, Jiucai ZHANG, Donghua ZHU, Jinchi ZHANG, Guorong LI
  • Patent number: 11246866
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: February 15, 2022
    Assignee: AbbVie Inc.
    Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
  • Publication number: 20200282004
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Application
    Filed: October 16, 2019
    Publication date: September 10, 2020
    Applicant: AbbVie Inc.
    Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
  • Publication number: 20200253968
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Application
    Filed: October 16, 2019
    Publication date: August 13, 2020
    Applicant: AbbVie Inc.
    Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
  • Publication number: 20190216882
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Application
    Filed: December 20, 2018
    Publication date: July 18, 2019
    Applicant: AbbVie Inc.
    Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
  • Publication number: 20190202812
    Abstract: The present invention features crystalline polymorphs of dimethyl (2S,2?S)-1,1,-((2S,2?S)-2,2,-(4,4,-((2S,5S)-1-(4-tert-butylphenyl) pyrrolidine-2,5-diyl) bis (4,1-phenylene)) bis (azanediyl) bis (oxomethylene) bis (pyrrolidine-2,1-diyl)) bis (3-methyl-1-oxobutane-2,1-diyl) dicarbamate i.e. ombitasvir, compound (I), which is a potent HCV NS5A inhibitor. In one embodiment, a crystalline form of Compound (I) has characteristic peaks in the PXRD pattern as shown in one of FIGS. 1-11.
    Type: Application
    Filed: April 25, 2017
    Publication date: July 4, 2019
    Applicant: AbbVie Inc.
    Inventors: Paul J. Brackemeyer, Colleen C. Garrett, Fredrik Lars Nordstrom, Ahmad Y. Sheikh, Geoff G. Zhang, Donghua Zhu
  • Patent number: 9798691
    Abstract: The present invention relates to a control circuitry module group, an electrical device, and a modem device. The control circuitry module group is configured for communication and/or power supply between a master control module and at least one slave modules in an electrical device. The control circuitry module group comprises: a bus; a bus control module coupled to the master control module and the bus, configured to receive a control signal from the master control module, add a target address in the control signal, and send to the bus the control signal with the target address; and at least one slave control modules each coupled to a corresponding slave module and the bus, respectively, and configured to receive the control signal with the target address via the bus, and controlling power supply to the slave module in response to the control signal.
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: October 24, 2017
    Assignee: Tyco Electronics (Shanghai) Co. Ltd.
    Inventors: Mingjie Fan, Junying Liu, Yuming Song, Donghua Zhu
  • Publication number: 20160375087
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Application
    Filed: June 24, 2016
    Publication date: December 29, 2016
    Applicant: AbbVie Inc.
    Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
  • Publication number: 20160375017
    Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
    Type: Application
    Filed: July 18, 2016
    Publication date: December 29, 2016
    Applicant: AbbVie Inc.
    Inventors: Katharina Asmus, Yi Gao, Colleen Garrett, Harald Hach, Adivaraha Jayasankar, Kyeremateng Samuel, Ute Lander, Thomas Mueller, Marius Naris, Constanze Obermiller, Regina Reul, Katrin Schneider, Nancy Sever, Michael Simon, Benedikt Steitz, Ping Tong, Ulrich Westedt, Donghua Zhu
  • Publication number: 20150322108
    Abstract: The present invention features crystalline forms of Compound I.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 12, 2015
    Inventors: Colleen C. Garrett, Lars Fredrik Nordstroem, Donghua Zhu
  • Publication number: 20150143007
    Abstract: The present invention relates to a control circuitry module group, an electrical device, and a modem device. The control circuitry module group is configured for communication and/or power supply between a master control module and at least one slave modules in an electrical device. The control circuitry module group comprises: a bus; a bus control module coupled to the master control module and the bus, configured to receive a control signal from the master control module, add a target address in the control signal, and send to the bus the control signal with the target address; and at least one slave control modules each coupled to a corresponding slave module and the bus, respectively, and configured to receive the control signal with the target address via the bus, and controlling power supply to the slave module in response to the control signal.
    Type: Application
    Filed: April 8, 2013
    Publication date: May 21, 2015
    Inventors: Mingjie Fan, Junying Liu, Yuming Song, Donghua Zhu
  • Patent number: D860167
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: September 17, 2019
    Inventor: Donghua Zhu
  • Patent number: D985147
    Type: Grant
    Filed: June 25, 2021
    Date of Patent: May 2, 2023
    Inventor: DongHua Zhu
  • Patent number: D997908
    Type: Grant
    Filed: June 25, 2021
    Date of Patent: September 5, 2023
    Inventor: DongHua Zhu
  • Patent number: D1011553
    Type: Grant
    Filed: June 25, 2021
    Date of Patent: January 16, 2024
    Inventor: DongHua Zhu