Patents by Inventor Donghua Zhu
Donghua Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240075026Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: ApplicationFiled: February 8, 2023Publication date: March 7, 2024Applicant: AbbVie Inc.Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
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Publication number: 20240000749Abstract: The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient; and one of or a combination of methacrylic acid copolymer, or a cellulose derivative wherein the active pharmaceutical ingredient is a dengue viral replication inhibitor. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of prevention and/or treatment and/or inhibition of viral replication are also described.Type: ApplicationFiled: November 3, 2021Publication date: January 4, 2024Inventors: Donghua Zhu, Kristof Leonard Kimpe, Sune Klint Andersen, Matthieu Jean M. Ravelingien, Ivan Henri M. Somers
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Publication number: 20230310413Abstract: Described herein are pharmaceutical formulations comprising a MALT1 inhibitor and a mixture comprising fatty acid and polyethylene glycol monoesters and diesters, and optionally, fatty acid and glycerol monoesters, diesters and triesters. Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.Type: ApplicationFiled: August 20, 2021Publication date: October 5, 2023Inventors: Sanket Manoj SHAH, Donghua ZHU, René HOLM, Kristof Leonard KIMPE
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Publication number: 20230301924Abstract: The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient, glyceryl palmitostearate, and D-?-tocopherol polyethylene glycol succinate (TPGS). Solid dosage forms comprising said pharmaceutical formulations, processes for preparing these and their use in methods of treatment are also described.Type: ApplicationFiled: November 3, 2021Publication date: September 28, 2023Inventors: Donghua Zhu, Kristof Leonard Kimpe, Kim Alda Verwaest
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Publication number: 20220405517Abstract: A system and method for recognizing traffic signs during autonomous driving comprises a camera module obtaining a first recognition, a sensor obtains behavior information of the host vehicle and of nearby vehicles and a connected training module generates parameters for traffic sign recognition according to information as to the behavior of the host vehicle and the nearby vehicles. A recurrent neural network module is connected with the training module and the camera module, and outputs a second traffic sign recognition according to the parameters and the first recognition. Training parameters of the second recognition comprise the traffic sign recognition parameters and the first recognition, the accuracy of the training result being improved by combining other sensors to perform traffic sign recognition training.Type: ApplicationFiled: June 17, 2021Publication date: December 22, 2022Inventors: Xiaosheng SHI, Jiucai ZHANG, Donghua ZHU, Jinchi ZHANG, Guorong LI
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Patent number: 11246866Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: GrantFiled: October 16, 2019Date of Patent: February 15, 2022Assignee: AbbVie Inc.Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
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Publication number: 20200282004Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: ApplicationFiled: October 16, 2019Publication date: September 10, 2020Applicant: AbbVie Inc.Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
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Publication number: 20200253968Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: ApplicationFiled: October 16, 2019Publication date: August 13, 2020Applicant: AbbVie Inc.Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
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Publication number: 20190216882Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: ApplicationFiled: December 20, 2018Publication date: July 18, 2019Applicant: AbbVie Inc.Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
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Publication number: 20190202812Abstract: The present invention features crystalline polymorphs of dimethyl (2S,2?S)-1,1,-((2S,2?S)-2,2,-(4,4,-((2S,5S)-1-(4-tert-butylphenyl) pyrrolidine-2,5-diyl) bis (4,1-phenylene)) bis (azanediyl) bis (oxomethylene) bis (pyrrolidine-2,1-diyl)) bis (3-methyl-1-oxobutane-2,1-diyl) dicarbamate i.e. ombitasvir, compound (I), which is a potent HCV NS5A inhibitor. In one embodiment, a crystalline form of Compound (I) has characteristic peaks in the PXRD pattern as shown in one of FIGS. 1-11.Type: ApplicationFiled: April 25, 2017Publication date: July 4, 2019Applicant: AbbVie Inc.Inventors: Paul J. Brackemeyer, Colleen C. Garrett, Fredrik Lars Nordstrom, Ahmad Y. Sheikh, Geoff G. Zhang, Donghua Zhu
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Patent number: 9798691Abstract: The present invention relates to a control circuitry module group, an electrical device, and a modem device. The control circuitry module group is configured for communication and/or power supply between a master control module and at least one slave modules in an electrical device. The control circuitry module group comprises: a bus; a bus control module coupled to the master control module and the bus, configured to receive a control signal from the master control module, add a target address in the control signal, and send to the bus the control signal with the target address; and at least one slave control modules each coupled to a corresponding slave module and the bus, respectively, and configured to receive the control signal with the target address via the bus, and controlling power supply to the slave module in response to the control signal.Type: GrantFiled: April 8, 2013Date of Patent: October 24, 2017Assignee: Tyco Electronics (Shanghai) Co. Ltd.Inventors: Mingjie Fan, Junying Liu, Yuming Song, Donghua Zhu
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Publication number: 20160375087Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: ApplicationFiled: June 24, 2016Publication date: December 29, 2016Applicant: AbbVie Inc.Inventors: Nancy E. Sever, Ulrich Westedt, Ute Lander, Katrin Schneider, Benedikt Steitz, Thomas Mueller, Regina Reul, Constanze Obermiller, Adivaraha Jayasankar, Michael Simon, Yi Gao, Harald Hach, Samuel Kyeremateng, Katharina Asmus, Ping Tong, Donghua Zhu, Marius Naris, Colleen Garrett
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Publication number: 20160375017Abstract: The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.Type: ApplicationFiled: July 18, 2016Publication date: December 29, 2016Applicant: AbbVie Inc.Inventors: Katharina Asmus, Yi Gao, Colleen Garrett, Harald Hach, Adivaraha Jayasankar, Kyeremateng Samuel, Ute Lander, Thomas Mueller, Marius Naris, Constanze Obermiller, Regina Reul, Katrin Schneider, Nancy Sever, Michael Simon, Benedikt Steitz, Ping Tong, Ulrich Westedt, Donghua Zhu
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Publication number: 20150322108Abstract: The present invention features crystalline forms of Compound I.Type: ApplicationFiled: May 9, 2014Publication date: November 12, 2015Inventors: Colleen C. Garrett, Lars Fredrik Nordstroem, Donghua Zhu
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Publication number: 20150143007Abstract: The present invention relates to a control circuitry module group, an electrical device, and a modem device. The control circuitry module group is configured for communication and/or power supply between a master control module and at least one slave modules in an electrical device. The control circuitry module group comprises: a bus; a bus control module coupled to the master control module and the bus, configured to receive a control signal from the master control module, add a target address in the control signal, and send to the bus the control signal with the target address; and at least one slave control modules each coupled to a corresponding slave module and the bus, respectively, and configured to receive the control signal with the target address via the bus, and controlling power supply to the slave module in response to the control signal.Type: ApplicationFiled: April 8, 2013Publication date: May 21, 2015Inventors: Mingjie Fan, Junying Liu, Yuming Song, Donghua Zhu
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Patent number: D860167Type: GrantFiled: January 5, 2018Date of Patent: September 17, 2019Inventor: Donghua Zhu
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Patent number: D985147Type: GrantFiled: June 25, 2021Date of Patent: May 2, 2023Inventor: DongHua Zhu
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Patent number: D997908Type: GrantFiled: June 25, 2021Date of Patent: September 5, 2023Inventor: DongHua Zhu
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Patent number: D1011553Type: GrantFiled: June 25, 2021Date of Patent: January 16, 2024Inventor: DongHua Zhu