Abstract: A full-face shaft tunnel boring machine system includes a tunnel boring machine cutterhead device for tunneling downwards in a shaft; a full-hydraulic formwork device for supporting and walling in a wellbore; and an upper muck-discharge system for vertically conveying rock mucks generated by tunneling. The tunnel boring machine cutterhead device comprises a vertical guide frame, a cutter-expanded boring head and an advanced cutterhead that are fixedly connected in a vertical order from top to bottom so as to form an integrated structure. The vertical guide frame is a hollow cylindrical structure and driven to rotate around an axis of the vertical guide frame by a power mechanism, and an outer wall of the vertical guide frame is provided with multiple sets of first guide rollers.

Abstract: Provided are a fluid circulation system and a method for operating same, a computer-readable medium, and a controller. The fluid circulation system comprises: a scroll expander, and an external fluid circulation path, which comprises a high-pressure fluid pipe and a low-pressure fluid pipe. The operation method comprises the following steps: before fluid is supplied to the scroll expander, making the fluid pressure in the high-pressure fluid pipe higher than the fluid pressure in the low-pressure fluid pipe by a pre-determined pressure difference; and after the pre-determined pressure difference is realized, starting the scroll expander and supplying fluid to the scroll expander. According to the present disclosure, the technical problem of a scroll expander being unable to be normally started and work can be avoided, and the invention is simple, practical, convenient, and easily implemented.

Abstract: Disclosed are a fluid pumping device and a horizontal compressor. The fluid pumping device comprises a pump structure in the form of an internal-meshing gear pump and is provided with first and second pump members, a pump housing structure for accommodating the pump structure, and at least two suction paths and/or at least two discharge paths. Suction and compression cavities are defined between the first and second pump members; the at least two suction paths are configured to rotate with the pump structure, and a fluid can be sucked into the suction cavity via the at least two suction paths respectively; and the at least two discharge paths are configured to rotate with the pump structure, and the compressed fluid can be discharged from the fluid pumping device via the discharge paths respectively. The fluid pumping device is assembled in the horizontal compressor.

Abstract: The present disclosure application relates to a construction method of a yeast display library (YSD), specifically to a construct for a yeast display library, an expression vector, a host cell and a construction method and use thereof. The yeast display library provided by the present application has high transformation efficiency and rich diversity.

Abstract: An expander and a fluid circulation system comprising same are disclosed. The expander comprises a housing, an expansion mechanism, an exhaust pipe, an oil sump and a lubricant discharge channel. The expansion mechanism is provided in the housing to expand a high-pressure fluid into a low-pressure fluid. The exhaust pipe discharges the low-pressure fluid out of the expander and comprises an end portion assembled in a first opening of the housing and provided with an exhaust port; the low-pressure fluid enters the exhaust pipe via the exhaust port. The oil sump stores a lubricant in the housing. The lubricant discharge channel discharges the lubricant in the oil sump into the exhaust pipe and/or an external system pipeline and comprises an inlet end having an inlet located at a predetermined oil level of the oil sump and an outlet end having an outlet.

Abstract: Provided are a fluid circulation system and a method for operating same, a computer-readable medium, and a controller. The fluid circulation system comprises: a scroll expander, and an external fluid circulation path, which comprises a high-pressure fluid pipe and a low-pressure fluid pipe. The operation method comprises the following steps: before fluid is supplied to the scroll expander, making the fluid pressure in the high-pressure fluid pipe higher than the fluid pressure in the low-pressure fluid pipe by a pre-determined pressure difference; and after the pre-determined pressure difference is realized, starting the scroll expander and supplying fluid to the scroll expander. According to the present disclosure, the technical problem of a scroll expander being unable to be normally started and work can be avoided, and the invention is simple, practical, convenient, and easily implemented.

Abstract: A scroll expander, comprising: a housing; and an expansion mechanism provided in the housing. A back pressure chamber in fluid communication with a medium pressure chamber is provided in the expansion mechanism and is provided with at least one passage in fluid communication from the back pressure chamber to a low pressure region; the passage is configured such that: the passage is opened when the pressure in the back pressure chamber is lower than the pressure of the low pressure region, and is closed when the pressure in the back pressure chamber is higher than or equal to the pressure of the low pressure region. The scroll expander can avoid the problem of being unable to be started and to operate normally; and the scroll expander is simple in structure, easy to process and manufacture, and high in cost effectiveness.

Abstract: The present application relates to a system and a method for effectively screening and assessing agents for tumor immunotherapy, which includes assessment for the effects of target cells, non-target cells, and tumor infiltration. The system and method of the present application can be used to comprehensively and systematically assess the effectiveness and safety of the agent against tumor immune cells.

Abstract: The present disclosure application relates to a construction method of a yeast display library (YSD), specifically to a construct for a yeast display library, an expression vector, a host cell and a construction method and use thereof. The yeast display library provided by the present application has high transformation efficiency and rich diversity.

Abstract: A scroll expander, comprising: a housing; and an expansion mechanism provided in the housing. A back pressure chamber in fluid communication with a medium pressure chamber is provided in the expansion mechanism and is provided with at least one passage in fluid communication from the back pressure chamber to a low pressure region; the passage is configured such that: the passage is opened when the pressure in the back pressure chamber is lower than the pressure of the low pressure region, and is closed when the pressure in the back pressure chamber is higher than or equal to the pressure of the low pressure region. The scroll expander can avoid the problem of being unable to be started and to operate normally; and the scroll expander is simple in structure, easy to process and manufacture, and high in cost effectiveness.

Abstract: The present invention relates to a compound represented by formula I, a pharmaceutical composition containing the compound of formula I, a method for inhibiting indoleamine 2,3-dioxygenase, and its use in medicine.

Abstract: An expander and a fluid circulation system comprising same are disclosed. The expander comprises a housing, an expansion mechanism, an exhaust pipe, an oil sump and a lubricant discharge channel. The expansion mechanism is provided in the housing to expand a high-pressure fluid into a low-pressure fluid. The exhaust pipe discharges the low-pressure fluid out of the expander and comprises an end portion assembled in a first opening of the housing and provided with an exhaust port; the low-pressure fluid enters the exhaust pipe via the exhaust port. The oil sump stores a lubricant in the housing. The lubricant discharge channel discharges the lubricant in the oil sump into the exhaust pipe and/or an external system pipeline and comprises an inlet end having an inlet located at a predetermined oil level of the oil sump and an outlet end having an outlet.

Abstract: Disclosed are a fluid pumping device and a horizontal compressor. The fluid pumping device comprises a pump structure in the form of an internal-meshing gear pump and is provided with first and second pump members, a pump housing structure for accommodating the pump structure, and at least two suction paths and/or at least two discharge paths. Suction and compression cavities are defined between the first and second pump members; the at least two suction paths are configured to rotate with the pump structure, and a fluid can be sucked into the suction cavity via the at least two suction paths respectively; and the at least two discharge paths are configured to rotate with the pump structure, and the compressed fluid can be discharged from the fluid pumping device via the discharge paths respectively. The fluid pumping device is assembled in the horizontal compressor.

Abstract: The disclosure relates to a cryoablation catheter and a cryoablation system. The cryoablation catheter comprises a catheter body and a freezing unit. The catheter body comprises a cold-source fluid input lumen and a cold-source fluid output lumen, both extending in an axial direction of the catheter body, and the freezing unit is arranged at a distal portion of the catheter body, and comprises a first balloon in fluid communication with the cold-source fluid input lumen and the cold-source fluid output lumen, and a second balloon arranged external to the first balloon with the length of the first balloon being less than the length of the second balloon. When the first balloon and the second balloon are dilated, a cavity is formed between the first balloon and the second balloon, to prevent the energy transfer in a space of the freezing unit corresponding to the cavity.

Abstract: The present invention relates to a compound represented by formula I, a pharmaceutical composition containing the compound of formula I, a method for inhibiting indoleamine 2,3-dioxygenase, and its use in medicine.

Abstract: Disclosed is a method for testing quality of powder spreading, including: illuminating, after a powder spreading apparatus completes spreading of a single layer of powder, a forming area successively and separately by light sources, and performing photographing twice to obtain two images of powder spreading; synthesizing the two images of powder spreading; determining an overall gray scale of the synthesized image, and if the overall gray scale is consistent, the powder spreading being successful, and if not, processing the synthesized image by using a method of gray scale threshold segmentation, and marking an area contained in a contour boundary inside the synthesized image as a suspected defect area; and determining whether the powder spreading is successful according to a gray scale value. Also disclosed is a device for testing the quality of powder spreading. The present application realizes a function of testing the quality of powder spreading.

Abstract: Disclosed is a method for testing quality of powder spreading, including: illuminating, after a powder spreading apparatus completes spreading of a single layer of powder, a forming area successively and separately by light sources, and performing photographing twice to obtain two images of powder spreading; synthesizing the two images of powder spreading; determining an overall gray scale of the synthesized image, and if the overall gray scale is consistent, the powder spreading being successful, and if not, processing the synthesized image by using a method of gray scale threshold segmentation, and marking an area contained in a contour boundary inside the synthesized image as a suspected defect area; and determining whether the powder spreading is successful according to a gray scale value. Also disclosed is a device for testing the quality of powder spreading. The present application realizes a function of testing the quality of powder spreading.

Abstract: An anti-virus system for enforcing a virus monitoring and scanning process, the anti-virus and firewall system comprises a master CPU card, a plurality of slave CPU cards and a programmable logic. The master CPU card is used for controlling the virus monitoring and scanning process and dividing the virus monitoring and scanning process into a plurality of sub-processes. The plurality of slave CPU cards are controlled by the master CPU card in a software level and a hardware level, each of the plurality of slave CPU cards receives and processes one of the plurality of sub-processes then sends back to the master CPU card. The programmable logic controlled by the master CPU card for monitoring and controlling said plurality of slave CPU cards at a hardware level.

Abstract: An anti-virus system for enforcing a virus monitoring and scanning process, the anti-virus and firewall system comprises a master CPU card, a plurality of slave CPU cards and a programmable logic. The master CPU card is used for controlling the virus monitoring and scanning process and dividing the virus monitoring and scanning process into a plurality of sub-processes. The plurality of slave CPU cards are controlled by the master CPU card in a software level and a hardware level, each of the plurality of slave CPU cards receives and processes one of the plurality of sub-processes then sends back to the master CPU card. The programmable logic controlled by the master CPU card for monitoring and controlling said plurality of slave CPU cards at a hardware level.