Abstract: Provided are a polymer compound and a composition for nucleic acid delivery comprising the same, wherein the polymer compound has a high binding affinity to nucleic acids and effectively protects nucleic acids from nucleases, thereby improving the nucleic acid delivery effect and stability.

Abstract: A composition according to an embodiment includes a selenium-containing material and an antioxidant. The composition may inhibit degeneration of cartilage by a mechanism such as reducing oxidative stress in cells constituting the cartilage. Accordingly, it is possible to inhibit an occurrence of osteoarthritis, delay its progression, or enable treatment of osteoarthritis.

Abstract: A flexible ultrasound transducer according to an embodiment of the present disclosure includes a substrate having a central part and a plurality of extended parts extending from the central part; an ultrasound probe disposed at the central part of the substrate to acquire an ultrasound image of a region of interest; and a focused ultrasound output unit disposed at the extended parts of the substrate to output a focused ultrasound to the region of interest, wherein the focused ultrasound output unit disposed at the extended parts of the substrate has a flexible property and is deformable. According to the structure of an embodiment, it is possible to simultaneously achieve ultrasound imaging and ultrasonic therapy such as lesion stimulation or removal through focused ultrasound, and adjust the focal position of focused ultrasound or improve the focal sensitivity through flexible movement.

Abstract: The present disclosure relates to a method for determining a relative position between arrays of a flexible array device. The flexible array device according to an embodiment includes a plurality of arrays arranged at a predetermined interval in a deformable substrate, and the method includes measuring the first capacitance between adjacent arrays, measuring the second capacitance between the adjacent arrays after deformation of the substrate, and determining a relative position between the adjacent arrays based on the first capacitance measurement value and the second capacitance measurement value. According to an embodiment, the relative position between the arrays may be determined by measuring the capacitance between the adjacent arrays of the plurality of arrays arranged in the deformable substrate and measuring a change in capacitance caused by the deformation (contraction, relaxation, bending) of the substrate.

Abstract: The present invention relates to a method for preparing a 3D biological bilayer membrane structure in a physiological buffer solution and a 3D biological bilayer membrane structure using the same, and more particularly, to a method for preparing a 3D biological bilayer membrane structure that is tightly sealed even under physiological ionic conditions by applying pressure during electroformation to improve a membrane fusion function, and a 3D biological bilayer membrane structure using the same.

Abstract: A method of fabricating a capacitive micromachined ultrasonic transducer (CMUT) according to one aspect of the present invention may include forming, on a semiconductor substrate, a first region implanted with impurity ions at a first average concentration and a second region implanted with no impurity ions or implanted with the impurity ions at a second average concentration lower than the first average concentration, forming an insulating layer by oxidizing the semiconductor substrate wherein the insulating layer includes a first oxide layer having a first thickness on at least a part of the first region and a second oxide layer having a second thickness smaller than the first thickness on at least a part of the second region, and forming a membrane layer on the insulating layer such that a gap is defined between the second oxide layer and the membrane layer.

Abstract: The present invention relates to a method for manufacturing a three-dimensional structure based on a block copolymer. The method comprises the steps of injecting a block copolymer (BCP) solution into each micro-well formed on the substrate and drying it to form a block copolymer layer, and applying a buffer to the block copolymer layer to hydrate the micro-well in three dimensions Forming the structure, after the three-dimensional structure is formed, injecting and curing a hydrogel solution around the three-dimensional structure may include the step of enhancing stability. In particular, the process of hydration by applying a buffer to the micro-well is performed while an electric field is applied. By controlling the concentration of the block copolymer (BCP) and the amplitude and frequency of the electric field, a three-dimensional artificial cell membrane having a desired size and shape, such as a spherical or ciliary shape and high stability (100% survival for 50 days) is manufactured can do.

Abstract: The present disclosure relates to a method for determining a relative position between arrays of a flexible array device. The flexible array device according to an embodiment includes a plurality of arrays arranged at a predetermined interval in a deformable substrate, and the method includes measuring the first capacitance between adjacent arrays, measuring the second capacitance between the adjacent arrays after deformation of the substrate, and determining a relative position between the adjacent arrays based on the first capacitance measurement value and the second capacitance measurement value. According to an embodiment, the relative position between the arrays may be determined by measuring the capacitance between the adjacent arrays of the plurality of arrays arranged in the deformable substrate and measuring a change in capacitance caused by the deformation (contraction, relaxation, bending) of the substrate.

Abstract: Provided is a method for matching antenna impedance in a wireless communication system. The method includes determining an approximate reflection coefficient based on an input signal and an output signal of a bidirectional coupler connected to a signal path of an antenna; determining an antenna impedance matching parameter corresponding to the determined approximate reflection coefficient by using a lookup table; and performing antenna impedance matching based on the antenna impedance matching parameter.

Abstract: A mesh type atomizer according to an embodiment includes a porous thin film having a multi-hole structure, a metal layer covering a remaining area except a nozzle area in which droplets are sprayed through the holes on a surface of the porous thin film, and an ultrasonic transducer to output ultrasonic waves to vibrate the porous thin film. According to an embodiment, it is possible to atomize a liquid into nanometer-level fine particles using the porous thin film including nanometer sized holes. It is possible to precisely adjust the sprayed droplet size by setting the shape, size and cycle of the nozzle in the manufacturing process, and it is possible to selectively increase the strength of the mesh by growing the metal material in the hole of the porous thin film through electroplating.

Abstract: A flexible ultrasound transducer according to an embodiment of the present disclosure includes a substrate having a central part and a plurality of extended parts extending from the central part; an ultrasound probe disposed at the central part of the substrate to acquire an ultrasound image of a region of interest; and a focused ultrasound output unit disposed at the extended parts of the substrate to output a focused ultrasound to the region of interest, wherein the focused ultrasound output unit disposed at the extended parts of the substrate has a flexible property and is deformable. According to the structure of an embodiment, it is possible to simultaneously achieve ultrasound imaging and ultrasonic therapy such as lesion stimulation or removal through focused ultrasound, and adjust the focal position of focused ultrasound or improve the focal sensitivity through flexible movement.

Abstract: The present invention pertains to an Internet of things platform which includes: a middleware that includes an apparatus management unit for receiving apparatus generated information from an Internet of things apparatus so as to establish a connection to the Internet of things apparatus, a service management unit for abstracting the Internet of things apparatus into a service apparatus and for controlling the Internet of things apparatus according to a service scenario, and a data management unit for generating and storing data regarding the apparatus management unit, the service management unit and the Internet of things apparatus; and a script editor that generates the service scenario for the service apparatus.

Abstract: Provided is a method for matching antenna impedance in a wireless communication system. The method includes determining an approximate reflection coefficient based on an input signal and an output signal of a bidirectional coupler connected to a signal path of an antenna; determining an antenna impedance matching parameter corresponding to the determined approximate reflection coefficient by using a lookup table; and performing antenna impedance matching based on the antenna impedance matching parameter.

Abstract: Provided is a method for matching antenna impedance in a wireless communication system. The method includes determining an approximate reflection coefficient based on an input signal and an output signal of a bidirectional coupler connected to a signal path of an antenna; determining an antenna impedance matching parameter corresponding to the determined approximate reflection coefficient by using a lookup table; and performing antenna impedance matching based on the antenna impedance matching parameter.

Abstract: The present invention pertains to an Internet of things platform which includes: a middleware that includes an apparatus management unit for receiving apparatus generated information from an Internet of things apparatus so as to establish a connection to the Internet of things apparatus, a service management unit for abstracting the Internet of things apparatus into a service apparatus and for controlling the Internet of things apparatus according to a service scenario, and a data management unit for generating and storing data regarding the apparatus management unit, the service management unit and the Internet of things apparatus; and a script editor that generates the service scenario for the service apparatus.

Abstract: A method for preparing a tightly sealed 3D lipid structure and a tightly sealed 3D lipid structure prepared thereby is disclosed. The method allows for simpler and more convenient preparation of an artificial biomembrane structure on a substrate using a lipid material, by using a plurality of transparent microwells formed on the substrate, and observation inside the microwells. In addition, a spherical 3D artificial single bilayer structure may be sealed very tightly through a simple method of changing the frequency of an electric field applied vertically to the microwells having a lipid layer formed. Through this, a biomimetic 3D structure having the structural and/or functional characteristics of a cell membrane constituting a cell can be provided more effectively.

Abstract: A method of fabricating a capacitive micromachined ultrasonic transducer (CMUT) according to one aspect of the present invention may include forming, on a semiconductor substrate, a first region implanted with impurity ions at a first average concentration and a second region implanted with no impurity ions or implanted with the impurity ions at a second average concentration lower than the first average concentration, forming an insulating layer by oxidizing the semiconductor substrate wherein the insulating layer includes a first oxide layer having a first thickness on at least a part of the first region and a second oxide layer having a second thickness smaller than the first thickness on at least a part of the second region, and forming a membrane layer on the insulating layer such that a gap is defined between the second oxide layer and the membrane layer.

Abstract: A method for preparing a tightly sealed 3D lipid structure and a tightly sealed 3D lipid structure prepared thereby is disclosed. The method allows for simpler and more convenient preparation of an artificial biomembrane structure on a substrate using a lipid material, by using a plurality of transparent microwells formed on the substrate, and observation inside the microwells. In addition, a spherical 3D artificial single bilayer structure may be sealed very tightly through a simple method of changing the frequency of an electric field applied vertically to the microwells having a lipid layer formed. Through this, a biomimetic 3D structure having the structural and/or functional characteristics of a cell membrane constituting a cell can be provided more effectively.

Abstract: Provided are a data discard method for a file system and a memory management apparatus thereof. Specifically, the data discard method for a file system includes: unlinking an inode and a data block corresponding to a file stored in a storage from among inodes and data blocks in a file system when a kernel event of deleting the file occurs; updating state values for the unlinked inode and data block, respectively, to a bitmap block of the file system; checking bit values of all of inodes in an inode block including the updated inode from among inode blocks of the file system; and transmitting discard commands with respect to the inode block including the updated inode and the data block, respectively, to the storage if all of the inodes of the inode block are clean bits as a result of the check.

Abstract: Provided is a method for matching antenna impedance in a wireless communication system. The method includes determining an approximate reflection coefficient based on an input signal and an output signal of a bidirectional coupler connected to a signal path of an antenna; determining an antenna impedance matching parameter corresponding to the determined approximate reflection coefficient by using a lookup table; and performing antenna impedance matching based on the antenna impedance matching parameter.