Patents by Inventor Dongjian Shi

Dongjian Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230052623
    Abstract: The present disclosure provides a word mining method and apparatus, an electronic device and a readable storage medium, and relates to the field of artificial intelligence technologies, such as natural language processing technologies, deep learning technologies, cloud service technologies, or the like.
    Type: Application
    Filed: July 12, 2022
    Publication date: February 16, 2023
    Applicant: BEIJING BAIDU NETCOM SCIENCE TECHNOLOGY CO., LTD.
    Inventors: Yang ZHANG, Shuangquan YANG, Lei HAN, Keke ZHOU, Yi XIE, Wei ZHOU, Junyi CHEN, Dongjian SHI, Guihua BAI, Xuan LI
  • Patent number: 11384162
    Abstract: The invention discloses a preparation method of a catechol group modified biomacromolecular scaffold material, comprising: grafting a catechol-containing compound by amidation to obtain modified biomacromolecules; then, allowing dopamine to perform oxidized self-polymerization in a weakly alkaline buffer solution to form polydopamine (PDA) particles with a uniform particle size; next, forming a scaffold which has three cross-linking structures, namely modified biomacromolecules, modified biomacromolecules/PDA, and biomacromolecules/PDA, through interaction between catechol groups, interaction between catechol groups and PDA particles, and interaction between macromolecules and PDA particles in the modified macromolecules respectively; and cross-linking the scaffold with calcium ions, adipic dihydrazide or genipin to further adjust the degree of cross-linking and porosity of the scaffold.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: July 12, 2022
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Dongjian Shi, Jiali Shen, Zhuying Zhang, Chuanhao Cao, Qian Zhao, Xiaojie Li, Mingqing Chen
  • Publication number: 20190062462
    Abstract: The invention discloses a preparation method of a catechol group modified biomacromolecular scaffold material, comprising: grafting a catechol-containing compound by amidation to obtain modified biomacromolecules; then, allowing dopamine to perform oxidized self-polymerization in a weakly alkaline buffer solution to form polydopamine (PDA) particles with a uniform particle size; next, forming a scaffold which has three cross-linking structures, namely modified biomacromolecules, modified biomacromolecules/PDA, and biomacromolecules/PDA, through interaction between catechol groups, interaction between catechol groups and PDA particles, and interaction between macromolecules and PDA particles in the modified macromolecules respectively; and cross-linking the scaffold with calcium ions, adipic dihydrazide or genipin to further adjust the degree of cross-linking and porosity of the scaffold.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 28, 2019
    Inventors: Dongjian SHI, Jiali SHEN, Zhuying ZHANG, Chuanhao CAO, Qian ZHAO, Xiaojie LI, Mingqing CHEN
  • Patent number: 8835570
    Abstract: A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the ?position of an ?,?-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the ?,?-unsaturated carboxyl group and one or more hydroxyl groups. In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained drug release material.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: September 16, 2014
    Assignees: Osaka University, Terumo Kabushiki Kaisha
    Inventors: Mitsuru Akashi, Michiya Matsusaki, Dongjian Shi, Makoto Onishi, Yotaro Fujita
  • Publication number: 20110257338
    Abstract: A hydrophilic material having a hydrophilic nature and being biocompatible and processable into nanoparticles wherein a hydrophilic monomer such as threitol or a hydrophilic polymer such as polyethylene glycol is attached to the ?position of an ?, ?-unsaturated carboxyl group of a (co)polymer comprising an aromatic compound such as 4-hydroxycinnamic acid in which an aromatic ring is substituted by the ?, ?-unsaturated carboxyl group and one or more hydroxyl groups. In particular, a hydrophilic material having a nanoparticle size which is highly dispersible in water, can well migrate into the blood and is useful as a drug carrier, a medical material and a sustained drug release material.
    Type: Application
    Filed: September 29, 2009
    Publication date: October 20, 2011
    Applicants: TERUMO KABUSHIKI KAISHA, OSAKA UNIVERSITY
    Inventors: Mitsuru Akashi, Michiya Matsusaki, Dongjian Shi, Makoto Onishi, Yotaro Fujita