Patents by Inventor Dongli Guan

Dongli Guan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR PURIFYING ADENO ASSOCIATED VIRUS PARTICLES OR ADENOVIRUSES
    Publication number: 20230183656
    Abstract: The present invention relates to compositions and methods for lysing cells and isolating and/or purifying adeno-associated virus particles or adenovirus particles using a detergent selected from the group of alkyldimethylamine oxides.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 15, 2023
    Applicant: Merck Patent GmbH
    Inventors: Moritz LEY, Eric WEISS, Ashish SAKSULE, Dongli GUAN, Herbert LUTZ
  • Intein mediated purification of protein
    Patent number: 10087213
    Abstract: The present invention includes methods, compositions, uses, and kits for purifying a protein of interest (POI) comprising contacting a first fusion protein comprising the POI fused to the C-terminus of an intein C-fragment with a second fusion protein comprising an intein N-fragment and a purification tag to form a complex between the first fusion protein and the second fusion protein, cleaving the POI from the intein C-fragment, wherein the protein is released from the complex; and isolating the POI; the present invention also includes fusion proteins and vector.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: October 2, 2018
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Zhilei Chen, Miguel A. Ramirez, Dongli Guan
  • Intein Mediated Purification of Protein
    Publication number: 20150353597
    Abstract: The present invention includes methods, compositions, uses, and kits for purifying a protein of interest (POI) comprising contacting a first fusion protein comprising the POI fused to the C-terminus of an intein C-fragment with a second fusion protein comprising an intein N-fragment and a purification tag to form a complex between the first fusion protein and the second fusion protein, cleaving the POI from the intein C-fragment, wherein the protein is released from the complex; and isolating the POI; the present invention also includes fusion proteins and vector.
    Type: Application
    Filed: January 10, 2014
    Publication date: December 10, 2015
    Inventors: Zhilei Chen, Miguel A. Ramirez, Dongli Guan