Patents by Inventor Donglim Esther PARK

Donglim Esther PARK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATMENT OF P53 WT TUMORS
    Publication number: 20210379039
    Abstract: The present invention relates to methods of treating p53 wild type (WT) tumors. In particular, the invention provides novel therapies for p53 WT tumors based on the combination of Mouse Double Minute 2 (MDM2) inhibitors, e.g. HDM201, together with Casein Kinase 1 alpha (CK1?) degrading agents and/or an MDM4 inhibitors, e.g. lenalidomide. The combination may be used in the treatment of solid as well as hematologic p53 WT tumors, e.g. Merkel cell carcinoma (MCC) or myelodysplastic syndrome (MDS).
    Type: Application
    Filed: October 28, 2019
    Publication date: December 9, 2021
    Inventors: Jingwei CHENG, James DECAPRIO, Donglim Esther PARK