Patents by Inventor Dongmei Xu

Dongmei Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12209249
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: September 28, 2023
    Date of Patent: January 28, 2025
    Assignee: Altria Client Services LLC
    Inventors: Dongmei Xu, Chengalrayan Kudithipudi, Yanxin Shen, Jaemo Yang, Jesse Frederick, James Strickland
  • Patent number: 12203082
    Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.
    Type: Grant
    Filed: December 15, 2021
    Date of Patent: January 21, 2025
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Yanxin Shen, Dongmei Xu, Jesse Frederick, Jaemo Yang
  • Patent number: 12193474
    Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.
    Type: Grant
    Filed: August 22, 2022
    Date of Patent: January 14, 2025
    Assignee: Altria Client Services LLC
    Inventors: Yahya Karga, James Powell, Dongmei Xu, James A. Strickland, Ujwala Warek
  • Publication number: 20250011803
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: September 25, 2024
    Publication date: January 9, 2025
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei XU, James Strickland
  • Patent number: 12163139
    Abstract: This disclosure provides a number of sequences involved in nitrogen utilization, methods of using such sequences, tobacco plants carrying modifications to such sequences, tobacco plants transgenic for such sequences, and tobacco products made from such plants.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: December 10, 2024
    Assignee: Altria Client Services LLC
    Inventors: Jesse Frederick, Chengalrayan Kudithipudi, Dongmei Xu
  • Publication number: 20240376488
    Abstract: The present disclosure provides approaches for reducing nicotine. Also provided are tobacco plants with decreased tobacco-specific nitrosamines (TSNAs). The present disclosure further provides modified tobacco plants with low nicotine and increased antioxidant capacity. Further provided are tobacco plants or material with low nicotine and low TSNAs. Also provided is cured tobacco material of the tobacco plants provided herein and tobacco products comprising this cured tobacco material.
    Type: Application
    Filed: July 24, 2024
    Publication date: November 14, 2024
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei XU, James A. STRICKLAND, Marcos Fernando de Godoy Lusso
  • Publication number: 20240365741
    Abstract: The present disclosure provides tobacco Nic1b locus and associated genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.
    Type: Application
    Filed: July 23, 2024
    Publication date: November 7, 2024
    Applicant: Altria Client Services LLC
    Inventors: Sreepriya PRAMOD, Marcos Fernando de GODOY LUSSO, Jesse FREDERICK, Andrew Carl ADAMS, Dongmei XU
  • Publication number: 20240368614
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: May 1, 2024
    Publication date: November 7, 2024
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei XU, James STRICKLAND, Yanxin SHEN
  • Patent number: 12129474
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Grant
    Filed: March 13, 2023
    Date of Patent: October 29, 2024
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Dongmei Xu, James Strickland
  • Publication number: 20240292804
    Abstract: The present disclosure provides tobacco Nic1b locus and associated genes (e.g., a group of ERF genes). Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.
    Type: Application
    Filed: January 26, 2024
    Publication date: September 5, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Sreepriya PRAMOD, Marcos Fernando de GODOY LUSSO, Jesse FREDERICK, Andrew Carl ADAMS, Dongmei XU
  • Patent number: 12075746
    Abstract: The present disclosure provides tobacco Nic1b locus and associated genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: September 3, 2024
    Assignee: Altria Client Services LLC
    Inventors: Sreepriya Pramod, Marcos Fernando de Godoy Lusso, Jesse Frederick, Andrew Carl Adams, Dongmei Xu
  • Patent number: 12077765
    Abstract: The present disclosure provides approaches for reducing nicotine. Also provided are tobacco plants with decreased tobacco-specific nitrosamines (TSNAs). The present disclosure further provides modified tobacco plants with low nicotine and increased antioxidant capacity. Further provided are tobacco plants or material with low nicotine and low TSNAs. Also provided is cured tobacco material of the tobacco plants provided herein and tobacco products comprising this cured tobacco material.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: September 3, 2024
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Dongmei Xu, James A. Strickland, Marcos Fernando de Godoy Lusso
  • Publication number: 20240218386
    Abstract: The present disclosure provides composition and methods for manipulating alkaloid or nicotine levels in tobacco plants. Also provided are the identification and genetic engineering of target genes (e.g., arginine decarboxylase (ADC), aspartate oxidase (AO), or ornithine decarboxylase (ODC)) for producing tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: December 2, 2020
    Publication date: July 4, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Chengalrayan KUDITHIPUDI, Yanxin SHEN, Dongmei XU
  • Patent number: 11999961
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: June 4, 2024
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Dongmei Xu, James Strickland, Yanxin Shen
  • Publication number: 20240156195
    Abstract: The present application provides a comfortable lightweight bullet-proof and stab-resistant suit and a preparation method thereof. A first aspect of the present application provides a comfortable lightweight bullet-proof and stab-resistant suit, including a sheath and a protection core sheet disposed in the sheath, and the protection core sheet includes a first protection layer, a second protection layer, a third protection layer and a buffer layer which are sequentially stacked together. The bullet-proof and stab-resistant suit provided in the present application has better response protection characteristics in the process of bullet penetration or knife tip stab, and the prepared aramid unidirectional cloth has low areal density, apparent flatness, no bubbles, and excellent softness, so that any bending within 180° can be realized.
    Type: Application
    Filed: April 25, 2023
    Publication date: May 16, 2024
    Inventors: Xinling FANG, Yuankun LIU, Dongmei XU, Qingsong AI, Hongxin LI, Hong CHEN, Zhaoyang LIU, Zhiyong PAN, Zhongwei WU, Zongjia LI, Nianhua LI, Liandong JIANG, Ruiling WANG, Long HU, Liqiang FU, Bing ZHANG, Junhong DAI, Fangning XUE
  • Publication number: 20240150783
    Abstract: This disclosure provides tobacco plants that exhibit altered photosynthesis as well as methods of making and using such plants.
    Type: Application
    Filed: November 9, 2023
    Publication date: May 9, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Yanxin SHEN, Dongmei XU
  • Patent number: 11970702
    Abstract: The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: April 30, 2024
    Assignee: U.S. Smokeless Tobacco Company LLC
    Inventors: Dongmei Xu, Mark T. Nielsen, Yanxin Shen
  • Publication number: 20240117371
    Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.
    Type: Application
    Filed: December 4, 2023
    Publication date: April 11, 2024
    Applicant: ALTRIA CLIENT SERVICES INC.
    Inventors: Chengalrayan KUDITHIPUDI, Alec J. HAYES, Robert Frank HART, III, Yanxin SHEN, Jesse FREDERICK, Dongmei XU
  • Publication number: 20240117370
    Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: November 22, 2023
    Publication date: April 11, 2024
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Marcos Fernando de GODOY LUSSO, James A. STRICKLAND, Jesse FREDERICK, Dongmei XU, Chengalrayan KUDITHIPUDI
  • Patent number: 11950563
    Abstract: The present disclosure provides tobacco Nic1b locus and associated genes (e.g., a group of ERF genes). Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: April 9, 2024
    Assignee: ALTRIA CLIENT SERVICES LLC
    Inventors: Sreepriya Pramod, Marcos Fernando de Godoy Lusso, Jesse Frederick, Andrew Carl Adams, Dongmei Xu