Abstract: A CRISPR regulatory system is disclosed. More particularly, the CRISPR regulatory system is useful for effectively regulating expression of a target gene and contains a Cas12f1 fusion protein and an engineered Cas12f1 guide RNA Uses of the CRISPR regulatory system are also disclosed. A method of regulating expression of a target gene by using a CRISPR regulatory system containing a Cas12f1 fusion protein and an engineered Cas12f1 guide RNA is also disclosed.

Abstract: The present invention relates to a branched copolymer having a polyimide polymer block bonded to each terminal of a branched polyamide functional group, and a photosensitive resin composition including the same, a photosensitive resin film, and an optical device.

Abstract: Provided is a method for producing a deuterated aromatic compound and a deuterated reaction composition. The method includes performing a deuterated reaction of an aromatic compound comprising one or more aromatic rings using a solution comprising the aromatic compound, heavy water, and an organic compound which can be hydrolyzed by the heavy water. The method produces a high-purity deuterated compound under relatively low temperature and pressure conditions.

Abstract: Provided is a method for producing a deuterated aromatic compound and a deuterated reaction composition. The method includes performing a deuterated reaction of an aromatic compound including one or more hydrocarbon aromatic rings using a solution comprising heavy water, an organic compound which can be hydrolyzed by the heavy water, the aromatic compound, and an organic solvent. The method has an advantage in that impurities due to hydrogen gas are not generated, the deuterium substitution rate is high, and the deuterated reaction can be performed under a lower pressure and a lower temperature.

Abstract: A photosensitive resin composition including a polyamide-imide resin having a specific structure, a film comprising a cured product of the photosensitive resin composition, a method for preparing the film and a method for forming a resist pattern using the photosensitive resin composition.

Abstract: The present specification relates to a method for producing a deuterated aromatic compound and a deuterated reaction composition.

Abstract: The present invention relates to a branched copolymer having a polyimide polymer block bonded to each terminal of a branched polyamide functional group, and a photosensitive resin composition including the same, a photosensitive resin film, and an optical device.

Abstract: A photosensitive resin composition including a polyamide-imide resin having a specific structure, a film comprising a cured product of the photosensitive resin composition, a method for preparing the film and a method for forming a resist pattern using the photosensitive resin composition.