Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of a Retroviridae infection, including an HIV infection.

Abstract: A cutter is provided to cut scrap wire into pieces. The cutter includes a base with a fixed shaft and a floating shaft parallel to the fixed shaft, a resilient connection device supporting the floating shaft, a master gear rotatably mounted on the fixed shaft, and a slave gear rotatably mounted on the floating shaft and engaging the master gear. Teeth of the master gear are pointed and an angle of the teeth of the master gear is less than 60°. A force provided by the resilient connection device is parallel to the center lines of the master gear and the slave gear, and when scrap wire is fed into the cutter, the master gear and the slave gear collectively cut the scrap wire into pieces.