Patents by Inventor Dongping Lin
Dongping Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200214563Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.Type: ApplicationFiled: March 19, 2020Publication date: July 9, 2020Inventor: Dongping Lin
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Patent number: 10660520Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.Type: GrantFiled: May 17, 2017Date of Patent: May 26, 2020Assignee: BRAEMAR MANUFACTURING, LLCInventor: Dongping Lin
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Publication number: 20190352589Abstract: An automated cell culture system includes a cell culture reactor including a housing; a fluidic circuit for cell culture media, the fluidic circuit disposed in an interior of the housing. The fluidic circuit includes a culture vessel for culturing cells in the cell culture media, a reservoir for the cell culture media, the reservoir fluidically connected to the culture vessel, and a pump configured to pump the cell culture media in the fluidic circuit. The automated cell culture system includes one or more sensors disposed in the interior of the housing, each sensor configured to detect a parameter of one or more of (1) the cell culture media in the fluidic circuit and (2) an environment in the interior of the housing; and a computing device configured to automatically control operation of the cell culture reactor based on one or more of the detected parameters.Type: ApplicationFiled: December 21, 2018Publication date: November 21, 2019Inventors: Jie Jing, Kenneth A. Collins, Fang Yuan, Zhonghua Zhang, Lawrence St. George, Jeffery J. Driscoll, Weijia Tan, Hao Cai, Dongping Lin, Jian Cheng
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Publication number: 20170367575Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.Type: ApplicationFiled: May 17, 2017Publication date: December 28, 2017Inventor: Dongping Lin
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Patent number: 9655518Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.Type: GrantFiled: March 27, 2009Date of Patent: May 23, 2017Assignee: BRAEMAR MANUFACTURING, LLCInventor: Dongping Lin
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Patent number: 8515529Abstract: Systems, methods, apparatus, and computer program products for detecting the existence of a sleep disorder in an individual using heart activity. In one aspect, machine-implemented methods include the actions of analyzing a machine-readable heart rate series of a monitored individual in the time domain using one or more digital data processing devices, detecting a cyclic variation in heart rate in the heart rate series as a result of the analysis in the time domain, and outputting, over an output, a report characterizing a sleep disorder event based on the detection of the cyclic variation in heart rate in the heart rate series. The cyclic variation in heart rate is indicative of a sleep disorder.Type: GrantFiled: February 12, 2009Date of Patent: August 20, 2013Assignee: Braemar Manufacturing, LLCInventors: Yachuan Pu, Charles Gropper, Dongping Lin
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Patent number: 8200319Abstract: Systems, devices, methods, and techniques relating to the identification of fiducial points. In one aspect, a machine implemented method includes obtaining a first time varying physiological signal and a second time varying physiological signal that relate to biological activity of an organism, the first time varying physiological signal and the second time varying physiological signal forming an analytic pair wherein the analytic pair has a time varying phase angle, defining a reference line by a lower boundary of a representation of the time varying phase angle with respect to a time period, and identifying a fiducial point based on the reference line.Type: GrantFiled: February 10, 2009Date of Patent: June 12, 2012Assignee: CardioNet, Inc.Inventors: Yachuan Pu, Charles Gropper, Dongping Lin
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Publication number: 20100249625Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.Type: ApplicationFiled: March 27, 2009Publication date: September 30, 2010Inventor: Dongping Lin
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Publication number: 20100204599Abstract: Systems, devices, methods, and techniques relating to the identification of fiducial points. In one aspect, a machine implemented method includes obtaining a first time varying physiological signal and a second time varying physiological signal that relate to biological activity of an organism, the first time varying physiological signal and the second time varying physiological signal forming an analytic pair wherein the analytic pair has a time varying phase angle, defining a reference line by a lower boundary of a representation of the time varying phase angle with respect to a time period, and identifying a fiducial point based on the reference line.Type: ApplicationFiled: February 10, 2009Publication date: August 12, 2010Inventors: Yachuan Pu, Charles Gropper, Dongping Lin
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Publication number: 20100204586Abstract: Systems, methods, apparatus, and computer program products for detecting the existence of a sleep disorder in an individual using heart activity. In one aspect, machine-implemented methods include the actions of analyzing a machine-readable heart rate series of a monitored individual in the time domain using one or more digital data processing devices, detecting a cyclic variation in heart rate in the heart rate series as a result of the analysis in the time domain, and outputting, over an output, a report characterizing a sleep disorder event based on the detection of the cyclic variation in heart rate in the heart rate series. The cyclic variation in heart rate is indicative of a sleep disorder.Type: ApplicationFiled: February 12, 2009Publication date: August 12, 2010Applicant: CardioNet, Inc.Inventors: Yachuan Pu, Charles Gropper, Dongping Lin
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Publication number: 20090131997Abstract: A defibrillator module is described which includes a cardiac sensor, a pulse generator and a controller that generates commands responsive to intrinsic cardiac signals for the operation of said pulse generator. The defibrillator module synergistic and arranged so that it can be coupled to a generic patient monitor so that the two can share certain functions. For example, operational parameters and other signals indicative of the operation of the defibrillator module can be shown to the clinician by the patient monitor. Data between the defibrillator module and the patient monitor is exchanged using either a standard or a customized protocol.Type: ApplicationFiled: December 2, 2008Publication date: May 21, 2009Inventors: Raymond W. Cohen, Dongping Lin, Mike Norton, Patrick Bradley, Gary Mezack, David Clark
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Patent number: 7006865Abstract: A defibrillator module is described which includes a cardiac sensor, a pulse generator and a controller that generates commands responsive to intrinsic cardiac signals for the operation of said pulse generator. The defibrillator module synergistic and arranged so that it can be coupled to a generic patient monitor so that the two can share certain functions. For example, operational parameters and other signals indicative of the operation of the defibrillator module can be shown to the clinician by the patient monitor. Data between the defibrillator module and the patient monitor is exchanged using either a standard or a customized protocol.Type: GrantFiled: March 9, 2000Date of Patent: February 28, 2006Assignee: Cardiac Science Inc.Inventors: Raymond W. Cohen, Dongping Lin, Mike Norton, Patrick Bradley, Gary Mezack, David Clark
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Publication number: 20060041278Abstract: A defibrillator module is described which includes a cardiac sensor, a pulse generator and a controller that generates commands responsive to intrinsic cardiac signals for the operation of said pulse generator. The defibrillator module synergistic and arranged so that it can be coupled to a generic patient monitor so that the two can share certain functions. For example, operational parameters and other signals indicative of the operation of the defibrillator module can be shown to the clinician by the patient monitor. Data between the defibrillator module and the patient monitor is exchanged using either a standard or a customized protocol.Type: ApplicationFiled: July 13, 2005Publication date: February 23, 2006Inventors: Raymond Cohen, Dongping Lin, Mike Norton, Patrick Bradley, Gary Mezack, David Clark
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Patent number: 6993386Abstract: A publically available external defibrillator includes a detector used to detect a life threatening condition of a patient, a controller operating the defibrillator automatically and a therapy delivery circuit that delivers appropriate therapy. The defibrillator is attached to a patient by any attendant or bystander and once it is attached, the defibrillator is adapted to monitor the patient and when a life threatening condition is detected, to apply therapy automatically, i.e., without any involvement by the patient or the attendant.Type: GrantFiled: October 16, 2003Date of Patent: January 31, 2006Assignee: Cardiac Science Inc.Inventors: Dongping Lin, Prabodh Mathur, Raul Ybarra
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Patent number: 6983183Abstract: A system to detect the presence or absence of T wave alternans is described based on statistical tests and periodicity transform. T wave and ST segment boundaries are detected in multi-lead ECG signals acquired from the regular clinical leads. Once the fiducial point and the above boundaries are delineated, computation of regular parameters like T wave amplitude, area under the T waves or segments of T wave, ST segment slope and/or the curvature of T wave are performed. Each parameter forms a rolling array of values with each successive beat. The array of values, or the time series, is used to make the decision about the T wave alternans. Two different methods are employed based on periodicity transforms and statistical tests. A set of numerical values (e.g. norm of the projection on to p-2 space, sums of adjacent terms after the trend removal, t-value, and number of deviations from alternans pattern) are all computed and compared to threshold values.Type: GrantFiled: July 13, 2001Date of Patent: January 3, 2006Assignee: Cardiac Science, Inc.Inventors: Srikanth Thiagarajan, Dongping Lin
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Publication number: 20040082972Abstract: A publically available external defibrillator includes a detector used to detect a life threatening condition of a patient, a controller operating the defibrillator automatically and a therapy delivery circuit that delivers appropriate therapy. The defibrillator is attached to a patient by any attendant or bystander and once it is attached, the defibrillator is adapted to monitor the patient and when a life threatening condition is detected, to apply therapy automatically, i.e., without any involvement by the patient or the attendant.Type: ApplicationFiled: October 16, 2003Publication date: April 29, 2004Inventors: Dongping Lin, Prabodh Mathur, Raul Ybarra
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Patent number: 6658290Abstract: A publically available external defibrillator includes a detector used to detect a life threatening condition of a patient, a controller operating the defibrillator automatically and a therapy delivery circuit that delivers appropriate therapy. The defibrillator is attached to a patient by any attendant or bystander and once it is attached, the defibrillator is adapted to monitor the patient and when a life threatening condition is detected, to apply therapy automatically, i.e., without any involvement by the patient or the attendant.Type: GrantFiled: June 12, 2000Date of Patent: December 2, 2003Assignee: Cardiac Science, Inc.Inventors: Dongping Lin, Prabodh Mathur, Raul Ybarra
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Publication number: 20030060724Abstract: A system to detect the presence or absence of T wave alternans is described based on statistical tests and periodicity transform. T wave and ST segment boundaries are detected in multi-lead ECG signals acquired from the regular clinical leads. Once the fiducial point and the above boundaries are delineated, computation of regular parameters like T wave amplitude, area under the T waves or segments of T wave, ST segment slope and/or the curvature of T wave are performed. Each parameter forms a rolling array of values with each successive beat. The array of values, or the time series, is used to make the decision about the T wave alternans. Two different methods are employed based on periodicity transforms and statistical tests. A set of numerical values (e.g. norm of the projection on to p-2 space, sums of adjacent terms after the trend removal, t-value, and number of deviations from alternans pattern) are all computed and compared to threshold values.Type: ApplicationFiled: July 13, 2001Publication date: March 27, 2003Inventors: Srikanth Thiagarajan, Dongping Lin
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Patent number: 6490478Abstract: A system and method based on electrocardiogram (ECG) complexity analysis for real-time detecting shockable ventricular fibrillation (VF) and ventricular tachycardia (VT), and discriminating them from non-shockable tachyarrhythmia (e.g. supraventricular tachycardia (SVT) and atrial fibrillation (AF)) and high-frequency noise. In the disclosed invention, complexity measure CM (0 to 100), quantitatively characterizing the complexity nature of the non-linear dynamics underlying cardiac arrhythmia, is extracted from the sensed patient ECG signal using ECG complexity analysis. From the calculated complexity measure, by three thresholds (low complexity threshold (LCT), mediate complexity threshold (MCT), and high complexity threshold (HCT)), different kinds of tachyarrhythmia (i.e.Type: GrantFiled: September 25, 2000Date of Patent: December 3, 2002Assignee: Cardiac Science Inc.Inventors: Xu-Sheng Zhang, Dongping Lin
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Patent number: 6480734Abstract: A cardiac monitor is provided that monitors the condition of the heart of a cardiac patient and generates signals indicating one of several conditions, such as supraventricular tachycardia, ventricular tachycardia and ventricular fibrillation. In order to generate these signals, the ECG from the patient is analyzed to determine a cardiac interval and heart rate, as well as a waveform factor and a waveform factor irregularity. The waveform factor is derived from the average of the ECG amplitudes during a cardiac interval and the peak value of the ECG during the same interval. Preferably, a running average is calculated over several intervals. This waveform factor is then used to detect shockable ventricular arrhythmia. The waveform factor irregularity is indicative of the variability of the waveform factor and is used to differentiate between ventricular tachycardia and ventricular defibrillation.Type: GrantFiled: June 30, 2000Date of Patent: November 12, 2002Assignee: Cardiac Science Inc.Inventors: Xu-Sheng Zhang, Dongping Lin