Patents by Inventor Dongping Ma

Dongping Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ATP DETECTION
    Publication number: 20230324390
    Abstract: The present disclosure relates to devices, methods, and systems or kits for detecting ATP in a sample. Particularly, the present disclosure relates to methods for removing ATP contamination from a sample and detecting intracellular ATP in the sample (e.g., as a proxy for detecting live cells in the sample).
    Type: Application
    Filed: April 6, 2023
    Publication date: October 12, 2023
    Inventors: Subhanjan Mondal, Dongping Ma, Kevin Hsiao, Said Goueli, James J. Cali
  • Quinone-masked probes as labeling reagents for cell uptake measurements
    Patent number: 9790537
    Abstract: Provided are labeling reagents and methods of using the reagents for cell uptake measurements. The labeling reagents can be quinone-masked probes including fluorophores and/or luminophores.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: October 17, 2017
    Assignee: Promega Corporation
    Inventors: Wenhui Zhou, Poncho Meisenheimer, Sarah Duellman, Dongping Ma, James J. Cali, Dana Mustafa
  • QUINONE-MASKED PROBES AS LABELING REAGENTS FOR CELL UPTAKE MEASUREMENTS
    Publication number: 20150307916
    Abstract: Provided are labeling reagents and methods of using the reagents for cell uptake measurements. The labeling reagents can be quinone-masked probes including fluorophores and/or luminophores.
    Type: Application
    Filed: January 29, 2015
    Publication date: October 29, 2015
    Inventors: Wenhui Zhou, Poncho Meisenhermier, Sarah Duellman, Dongping Ma, James J. Cali, Dana Mustafa
  • Bioluminescent assays using cyanobenzothiazole compounds
    Patent number: 8592172
    Abstract: The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: November 26, 2013
    Assignee: Promega Corporation
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz, James J. Cali, Dongping Ma
  • Bioluminescent detection of cyanohydroxy benzothiazole compounds
    Patent number: 8551721
    Abstract: The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: October 8, 2013
    Assignee: Promega Corporation
    Inventors: Jessica Anderson, Poncho Meisenheimer, John Shultz, James J. Cali, Dongping Ma
  • BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS
    Publication number: 20110223625
    Abstract: The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
    Type: Application
    Filed: March 11, 2011
    Publication date: September 15, 2011
    Applicant: PROMEGA CORPORATION
    Inventors: Jessica Kelts, Poncho Meisenheimer, John Shultz, James J. Cali, Dongping Ma
  • BIOLUMINESCENT DETECTION OF CYANOHYDROXY BENZOTHIAZOLE COMPOUNDS
    Publication number: 20100075351
    Abstract: The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.
    Type: Application
    Filed: September 9, 2009
    Publication date: March 25, 2010
    Applicant: Promega Corporation
    Inventors: Jessica Anderson, Poncho Meisenheimer, John Shultz, James J. Cali, Dongping Ma
  • Luminescent ATP detection with extended linearity
    Publication number: 20060234323
    Abstract: A luminescent assay capable of detecting a wider range of ATP concentrations is provided.
    Type: Application
    Filed: April 18, 2005
    Publication date: October 19, 2006
    Inventors: James Cali, Dongping Ma
  • Rapidly degraded reporter fusion proteins
    Publication number: 20040146987
    Abstract: A fusion polypeptide comprising a protein of interest which has a reduced half-life of expression, and a nucleic acid molecule encoding the fusion polypeptide, are provided.
    Type: Application
    Filed: September 16, 2003
    Publication date: July 29, 2004
    Applicant: Promega Corporation
    Inventors: Alexey Zdanovsky, Marina Zdanovskaia, Dongping Ma, Keith V. Wood, Brian Almond, Monika G. Wood