Abstract: A toy launcher is provided. The toy launcher achieves splicing extension of building blocks at any position on a surface of the toy launcher by arranging distributed building block connecting protrusions on outer side walls of a gun body and a sliding sleeve and matching with a building block connecting post of a detachable splicing device. Users can flexibly mount a functional module or a decorative building block unit on a top of the gun body, a side of a grip or a sliding sleeve according to individual requirements. The building block unit is a splicing device, which breaks through limitation of a closed shell of the existing toy launcher on extensibility. In addition, users can flexibly choose different numbers of splicing devices with different shapes for assembly.

Abstract: A proteomic screening method for anaerobic-specific and expression-effective promoter, and a method of specially delivering and selectively stably expressing target gene in anaerobic tissue by an alcohol dehydrogenase promoter and uses thereof. The latter comprises an anaerobically-induced alcohol dehydrogenase promoter which is used as target gene promoter, anaerobic target bacteria and low copy number plasmid. Therefore, the target gene can be specially and highly expressed under hypoxia condition in vivo or in vitro. The selective gene expression which is driven by the alcohol dehydrogenase promoter in anaerobic tissue can be used as gene therapy method to treat anaerobic tissue disease including tumor, or to prepare anti-tumor drug.

Abstract: A proteomic screening method for anaerobic-specific and expression-effective promoter, and a method of specially delivering and selectively stably expressing target gene in anaerobic tissue by an alcohol dehydrogenase promoter and uses thereof. The latter comprises an anaerobically-induced alcohol dehydrogenase promoter which is used as target gene promoter, anaerobic target bacteria and low copy number plasmid. Therefore, the target gene can be specially and highly expressed under hypoxia condition in vivo or in vitro. The selective gene expression which is driven by the alcohol dehydrogenase promoter in anaerobic tissue can be used as gene therapy method to treat anaerobic tissue disease including tumor, or to prepare anti-tumor drug.